Historic Cord Blood Transplant Could Cure HIV/AIDS
University of Minnesota physicians will perform the world's first cord blood transplant, which if successful, is designed to cure a pediatric patient of HIV/AIDS.
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University of Minnesota physicians will perform the world's first cord blood transplant, which if successful, is designed to cure a pediatric patient of HIV/AIDS.
A Minnesota father of three says his prayers were answered after WCCO shared his story over the summer.
It could be the first-ever surgery of its kind -- where a man's leg was actually transplanted onto his spine -- and it only came about because of an extraordinary way the patient met his doctor.
Many of us don't even know our neighbors, and won't even consider giving them a kidney.
Imagine that a hospital room is where you'll spend the holidays. It's a reality for a Duluth woman who has spent the past month in the Mayo Clinic.
The Minneapolis-based National Marrow Donor Program is celebrating its 50,000th transplant.
More than 100 medical devices have been recalled after a report showed that the U.S. Food and Drug Administration (FDA) process of approving them is flawed.
A little South Dakota boy named Drake Dosch is the lucky recipient of a medical achievement that has only happened 19 times in Minnesota history -- the transplant of the small bowel, a critical part of our intestines.
A Wisconsin boy who underwent a stem-cell transplant to strengthen his delicate skin is almost ready to come home from a Minneapolis hospital.
Ten-month-old Carolyn Cooper's mom and dad take no small developments for granted.
A 4-year-old Wisconsin boy born without the gene that binds skin together is heading to Minnesota to prepare for a stem-cell transplant that could save his life.
Jalen Smith scored his second touchdown a diving 12-yard catch in the first overtime and Minnesota extended its postseason winning streak to nine straight games with a 20-17 win over New Mexico in Rate Bowl.
The World Junior Championship tournament kicked off in Minnesota on Friday. For those eager to check it out, there's a free fan experience called the Bold North Breakaway.
The weeklong festival of Kwanzaa began on Friday with much fanfare at Lake Street's Midtown Global Market in Minneapolis.
As Christmas trees across the nation come down, a farm in Elk River, Minnesota, is finding a new purpose for the pines.
Over the holidays, a team of researchers and a University of Minnesota employee are hard at work in Antarctica. The scientists are drilling for ice millions of years old, deep beneath the surface.
The weeklong festival of Kwanzaa began on Friday with much fanfare at Lake Street's Midtown Global Market in Minneapolis.
Gov. Tim Walz has ordered U.S. and Minnesota flags at all state buildings to fly at half-staff on Monday to honor and remember St. Paul firefighter Timothy Bertz, who officials said died after suffering a "serious medical event."
Minneapolis officials have banned government officials, including U.S. Immigration and Customs Enforcement agents, from using city lots and ramps as a staging area to enforce federal immigration laws, according to an updated city ordinance.
Police in Roseville, Minnesota, are investigating after they said officers found a man injured at the scene of a reported shooting on Friday morning.
A lucky lottery player in Arkansas won the $1.817 billion Powerball drawing on Christmas Eve, but someone in the Twin Cities was also treated to a nice stocking stuffer in the form of $100,000.
As Christmas trees across the nation come down, a farm in Elk River, Minnesota, is finding a new purpose for the pines.
Gov. Tim Walz has ordered U.S. and Minnesota flags at all state buildings to fly at half-staff on Monday to honor and remember St. Paul firefighter Timothy Bertz, who officials said died after suffering a "serious medical event."
An ER patient is accused of attacking a security guard inside a Wyoming, Minnesota, hospital on Christmas evening, leading to a confrontation with a police officer outside the facility.
Hockey moms are a community, one that Jacqueline Nowakowski had no idea she'd need as much as she does.
Two women are dead after a semitruck collided with a Chrysler minivan in Elmer Township, Minnesota, on Christmas Eve, according to the Minnesota State Patrol.
A Wisconsin woman who almost killed her sixth-grade classmate to please the fictional Slender Man has been ordered back to a state psychiatric hospital after she escaped from her group home last month.
Several schools in Minnesota and Wisconsin are reporting delayed starts on Monday amid a messy morning commute.
The U.S. Justice Department has sued three states, including Illinois and Wisconsin, and D.C. for not turning over requested voter information to the Trump administration.
Defenders of a Wisconsin judge found guilty of felony obstruction for helping a Mexican immigrant evade federal officers are raising alarms about judicial independence and say they hope the conviction will be overturned on appeal.
The Minnesota Attorney General's Office says Menards, the Wisconsin-based home improvement retailer, has reached a $4.25 million settlement with several states to "resolve claims" of deceptive marketing practices in its popular "11% Rebate Program," and pandemic-era price gouging.
Many people who serve in the U.S. military find it hard to ask for assistance when they've been trained to help and serve others.
Food Bank Eatery in North Minneapolis provides free meals for children, who may have little to eat after the pause of SNAP benefits for many in the community.
Firefighters are continuing a 44-year tradition that happens every year north of the Twin Cities.
It was a scary moment in the Twin Cities over the weekend, as a trailer hauling sled dogs turned over on Interstate 494 in Minnetonka.
On Sunday, members of Minnesota's Somali community spoke out against President Trump's social media post calling for an end to temporary protected status.
Minneapolis officials have banned government officials, including U.S. Immigration and Customs Enforcement agents, from using city lots and ramps as a staging area to enforce federal immigration laws, according to an updated city ordinance.
The Veterans Affairs Department is reimposing a near total ban on abortions for veterans and their families that was modified in 2022.
President Trump says the U.S. launched powerful and deadly strikes against Islamic state forces in Nigeria, plus more of the day’s top stories.
Strikes against ISIS targets in Nigeria come after President Trump spent weeks accusing the West African country's government of failing to rein in the persecution of Christians.
The message, aired on Channel 4 on Christmas Day, reflected on the impact of President Trump's second term in office thus far.
This season of giving can really do a number on our recycling systems. But we can all be part of the solution.
With the time-honored tradition of gift giving comes gift concealing.
Twin Cities shoppers were out and about on Super Saturday, the second-busiest shopping day of the year. The day lands on the final Saturday before Christmas annually.
Buy now, pay later plans are becoming more popular for shoppers this holiday season.
The Minnesota Attorney General's Office says Menards, the Wisconsin-based home improvement retailer, has reached a $4.25 million settlement with several states to "resolve claims" of deceptive marketing practices in its popular "11% Rebate Program," and pandemic-era price gouging.
Police in Roseville, Minnesota, are investigating after they said officers found a man injured at the scene of a reported shooting on Friday morning.
Minneapolis police say they're investigating a "suspicious death" after a woman's body was discovered inside a vehicle Tuesday morning.
An ER patient is accused of attacking a security guard inside a Wyoming, Minnesota, hospital on Christmas evening, leading to a confrontation with a police officer outside the facility.
A 63-year-old West St. Paul, Minnesota, man accused of pointing a gun at a U.S. Immigration and Customs Enforcement agent says the agent also pointed a gun at him, according to court documents filed on Thursday.
Minneapolis police are investigating after they say a man suffered "potentially life-threatening injuries" in a stabbing on Thursday morning.
The clock is ticking to snag a few more gifts and prepare for that holiday trip to visit family. As the pressure builds, so does the stress.
The Minnesota Athletic Trainers Association says of the middle and high schools they know of, only 49% have an athletic trainer providing some level of service.
From 2021 to 2025, Smart Therapy Center submitted claims totaling $31.8 million across all Minnesota Department of Human Services programs, according to that data. But the provider was only approved for a fraction of those payments.
The family of a Minnesota Vikings player who died at training camp from heat exhaustion in 2001 is still fighting to protect others.
A Twin Cities metro area school shifted to e-learning after a flu outbreak impacted nearly a quarter of its students. A senior epidemiologist with the Minnesota Department of Health said flu season is "definitely picking up."
The band announced Perry Bamonte's death on their official website on Friday.
The message, aired on Channel 4 on Christmas Day, reflected on the impact of President Trump's second term in office thus far.
Feeding America's CEO said the organization is "incredibly grateful" for Taylor Swift's large donation.
The singer said an MRI showed a cancerous spot on one of his lungs after he recovered from a lengthy bout of bronchitis.
The special features interviews with Kathy Bates, Annette Bening, Albert Brooks, Michael Douglas, Kiefer Sutherland, Jerry O'Connell and Mandy Patinkin.
Jalen Smith scored his second touchdown a diving 12-yard catch in the first overtime and Minnesota extended its postseason winning streak to nine straight games with a 20-17 win over New Mexico in Rate Bowl.
The World Junior Championship tournament kicked off in Minnesota on Friday. For those eager to check it out, there's a free fan experience called the Bold North Breakaway.
The Minnesota Vikings are trying to practice the process of winning in December despite being eliminated from contention for the playoffs.
Hockey moms are a community, one that Jacqueline Nowakowski had no idea she'd need as much as she does.
Nikola Jokic set an NBA record with 18 points in overtime, leading the Denver Nuggets to a 142-138 win over the Minnesota Timberwolves on Christmas night.
Minnesota Congresswoman Ilhan Omar is calling for answers about the immigration crackdown in the Twin Cities. She is also denouncing the president's attacks on the Somali community and herself. In Talking Points, Esme Murphy shows us how, for Omar, this is a familiar position to be in.
Minnesota Congresswoman Ilhan Omar is calling for clarity about the immigration crackdown in the Twin Cities.
Fear and uncertainty continue in Minnesota's Somali communities as ICE continues its intensified focus on the Twin Cities.
Opposition to ICE actions is widespread among Democratic elected officials throughout the state, though nowhere more than in Minneapolis, home to the state's largest Somali population.
Minnesotans who welcomed a child this year were able to start applying this week to the state's new paid family and medical leave program to take time off in 2026.
On Dec. 9, 1965, "A Charlie Brown Christmas" debuted on CBS, and it became an instant classic. Lee Jenkins' home is proof that the show is still a hit six decades later.
Holiday lights are on full display across the state right now, and just south of the Twin Cities you'll find a Christmas light show that's been around for more than half a century.
The story begins years ago when the city acquired one of the T-38 Talon Thunderbird jets from the Air Force.
The holidays are upon us, and in the town of Kellogg, Minnesota, you'll find a toy store unlike any other.
With the holidays fast approaching, and lutefisk on the menu for many families, one Minnesota town has the distinction of being called the "Lutefisk Capital of the Country."
According to the Smithsonian Magazine and Britannica, eggnog has British roots.
With the time-honored tradition of gift giving comes gift concealing.
The story of "The Wizard of Oz " is 125 years old, yet still reinventing itself in all kinds of forms.
It's the time of year when we accumulate the most stuff. When we do, people often throw around the word "hoarding." But it turns out it's a frequently misunderstood term.
Why do we have oily or dry skin? A dermatologist explains the root cause and how it can change over time.
Minnesotans got a great view of the northern lights Tuesday night.
A look at the newest addition to the polar bear population at St. Paul, Minnesota's Como Zoo.
From food shelves to school programs, our team is proud to serve where it matters most.
The Minnesota State Fair has unveiled its new food, drinks and vendors for 2025.
A suspect was taken into custody after an attack on Pearl Street Mall in Boulder on June 1 in which there were 15 people and a dog who were victims. The suspect threw Molotov cocktails that burned some of the victims, who were part of a march for Israeli hostages.
High temperatures will be in the 30s and 40s across Minnesota on Saturday before colder weather moves in, according to NEXT Weather meteorologist Lisa Meadows.
In Minnesota, weather can be all over the place. Here at WCCO, we want to give you what you need to prepare for what's happening next.
Wind chills next week will dip below zero degrees, with cool and breezy conditions early in the week, according to NEXT Weather meteorologist Lisa Meadows.
NEXT Weather meteorologist Lisa Meadows says there's a chance for snow showers on Sunday afternoon and evening.
Friday will be another mild one in the Twin Cities, but another bitter blast is on the way, says NEXT Weather meteorologist Adam Del Rosso.
High temperatures will be in the 30s and 40s across Minnesota on Saturday before colder weather moves in, according to NEXT Weather meteorologist Lisa Meadows.
Minnesota is still reeling from the political assassination of DFL Speaker Emerita Melissa Hortman and her husband Mark, which happened in their home six months ago. Their beloved dog Gilbert also died in the attack. As Caroline Cummings shows, their legacy lives on in a way one local organization never expected.
The holiday season certainly doesn't end with Christmas. Dec. 26 marks the first day of Kwanzaa. As Jonah Kaplan reports, you're not alone if you're still unsure about what the holiday means. Those who do celebrate tell us that asking questions is at its core.
The 2026 World Junior Championship kicked off in the Twin Cities on Friday. There's a free fan experience in St. Paul. Frankie McLister explains what to expect.
Many people make their way to an airport during the holidays. While you might think of Minneapolis-St. Paul International Airport as a transient place where people are just passing through, there's a bright spot, a man who has become a mainstay there. Erin Hassanzadeh introduces shoeshine Danny.