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Quarterback Brock Purdy has been officially ruled out of his third straight game for the San Francisco 49ers with a toe injury and Mac Jones will start against the Atlanta Falcons.
Four-time All-Pro linebacker Fred Warner will need season-ending surgery after he was sidelined by a severe ankle injury during San Francisco's loss to Tampa Bay.
Baker Mayfield's heroics came early in the fourth quarter instead of the final minutes.
The San Francisco 49ers travel to Florida to face the Tampa Bay Buccaneers for NFL Week 6, and there are several ways to watch and stream the football game scheduled at 4:25 p.m. ET / 1:25 p.m. PT.
Quarterback Brock Purdy will miss his fourth game this season for San Francisco due to a toe injury.
Eddy Piñeiro has quickly become a fan favorite with the San Francisco 49ers.
San Francisco 49ers quarterback Brock Purdy is still sidelined by a toe injury and missed practice on Wednesday.
Eddy Piñeiro hit a 41-yard field goal in overtime before the San Francisco defense stopped Kyren Williams on fourth down with 3:36 to play, and the short-handed 49ers hung on for a thrilling 26-23 victory over the Los Angeles Rams on Thursday night.
The event, called TailG8, blends the spirit of a traditional tailgate with the energy of a block party. It's free and open to the public.
The injury-ravaged San Francisco 49ers will again be missing multiple starters with injuries for the Thursday night game against the Los Angeles Rams.
Quarterback Brock Purdy is dealing with a toe injury that has sidelined him for two games this season.
The San Francisco 49ers are dealing with injuries following their first loss of the season to the Jacksonville Jaguars.
One avid fan began documenting the parking lot celebrations and ended up as a bit of a celebrity at Levi's Stadium.
Parker Washington has scored Jacksonville's first punt return touchdown in eight seasons, leading the Jaguars to a 26-21 victory over the San Francisco 49ers.
Quarterback Brock Purdy returns for the San Francisco 49ers this week after missing two games with a toe injury.
The San Francisco 49ers have been winning games despite struggling with their usual ground game.
San Francisco 49ers star defensive lineman Nick Bosa will miss the rest of the season with a torn anterior cruciate ligament, the team confirmed Monday.
San Francisco 49ers star Nick Bosa left the win against the Arizona Cardinals with a knee injury.
Eddy Pineiro has kicked a 35-yard field goal to give the San Francisco 49ers a 16-15 win over the Arizona Cardinals.
Quarterback Brock Purdy is highly unlikely to start for the San Francisco 49ers on Sunday because of a toe injury.
The teen charged in the shooting of San Francisco 49ers wide receiver Ricky Pearsall will be tried in juvenile court, a judge ruled Friday, denying a motion by prosecutors to try the suspect as an adult.
San Francisco 49ers quarterback Brock Purdy returned to practice on Wednesday after missing a game with a toe injury.
Jones threw for 279 yards and a career-high-tying three touchdowns, and the banged-up 49ers defeated the Saints 26-21 on Sunday.
San Francisco 49ers quarterback Brock Purdy is dealing with a toe injury and is considered "week to week.".
The San Francisco 49ers announced the team signed veteran kicker Eddy Piñeiro Jr. to a one-year deal on Wednesday, a day after placing Jake Moody on waivers.
Hundreds gathered Friday night in Oakland for a tribute to coach John Beam and to celebrate his life. It was the first organized memorial for the coach since he was fatally shot on Nov. 13.
A housing controversy is brewing in San Francisco's Marina District, and even some pro-housing advocates are speaking out against a new development proposal.
Philanthropist Mackenzie Scott donated $50 million to Cal State East Bay, and the community is thrilled and grateful for the opportunities this funding will bring.
The Trump administration will start sending more water to California farmers in the state's crop-rich Central Valley.
A man convicted in the 2020 killing of a 19-year-old in San Francisco's Portola neighborhood will likely spend the rest of his life behind bars, prosecutors said.
Hundreds gathered Friday night in Oakland for a tribute to coach John Beam and to celebrate his life. It was the first organized memorial for the coach since he was fatally shot on Nov. 13.
A housing controversy is brewing in San Francisco's Marina District, and even some pro-housing advocates are speaking out against a new development proposal.
Philanthropist Mackenzie Scott donated $50 million to Cal State East Bay, and the community is thrilled and grateful for the opportunities this funding will bring.
The Trump administration will start sending more water to California farmers in the state's crop-rich Central Valley.
A man convicted in the 2020 killing of a 19-year-old in San Francisco's Portola neighborhood will likely spend the rest of his life behind bars, prosecutors said.
A housing controversy is brewing in San Francisco's Marina District, and even some pro-housing advocates are speaking out against a new development proposal.
A man convicted in the 2020 killing of a 19-year-old in San Francisco's Portola neighborhood will likely spend the rest of his life behind bars, prosecutors said.
San Francisco's newly appointed police chief, Derrick Lew, is taking office with an ambitious promise: "I truly believe we're entering a golden era in San Francisco."
A social worker was stabbed and severely injured Thursday inside Zuckerberg San Francisco General Hospital, authorities said.
An inmate at a San Francisco County Jail facility was taken to the hospital after being stabbed by another inmate Thursday afternoon, deputies said.
Hundreds gathered Friday night in Oakland for a tribute to coach John Beam and to celebrate his life. It was the first organized memorial for the coach since he was fatally shot on Nov. 13.
Philanthropist Mackenzie Scott donated $50 million to Cal State East Bay, and the community is thrilled and grateful for the opportunities this funding will bring.
Just a year after Alameda County District Attorney Pamela Price was recalled by nearly 63% of the voters, she's running again to get her job back.
The zoo has written a glowing love letter to the city of Oakland, in its new exhibit: The Future of Oakland.
About 1,500 teachers at the West Contra Costa Unified School District took to the picket lines on Thursday, striking over what they said were low pay and a lack of permanent staffing.
The mother of a newborn baby who was found dead in Monterey County in 1994 has pleaded guilty to her son's death, prosecutors said.
Officials in Monterey County have issued a warning to people foraging for wild mushrooms amid a rise in poisonings.
Kiara Manion opened Bloom with her husband during the COVID-19 pandemic, building a following around breakfast classics such as chicken and waffles. The restaurant has also become a go-to gathering place on San Francisco 49ers game days.
Santa Clara County District Attorney Jeff Rosen announced charges against the 17-year-old accused of shooting three people at San Jose's Westfield Valley Fair mall on Black Friday.
Two people were killed in a fiery multi-vehicle crash involving Teslas on Highway 87 in San Jose late Tuesday morning, authorities said.
Two people suspected of stealing nearly $100,000 in items from a construction site in Napa County were arrested following dual pursuits early Thursday, police said.
One of two people charged in the Santa Rosa killing of Mark Calgani, the general manger of San Francisco's Condor Club, has pleaded no contest in the case.
A California animal rights activist who took four chickens from a Perdue Farms poultry plant in Sonoma County was sentenced on Wednesday to 90 days in jail following her conviction in October.
Cal Fire said, around 3 p.m., crews were called to Bean Hollow State Beach near Pescadero for a report of a person in the water.
Marin County has passed some new regulations to prevent wildfires that will take effect on Jan. 1.
The 2026 Men's World Cup will be held across the United States, Canada and Mexico next summer.
California has hired Tosh Lupoi as the new head coach, bringing back the former Golden Bears player and assistant.
Rookie VJ Edgecombe and Tyrese Maxey each made huge plays in the final seconds as the Philadelphia 76ers beat the short-handed Golden State Warriors.
The Athletics are on track to open their new Las Vegas stadium on time, officials said Thursday.
Former Angels and Rangers manager Ron Washington is returning to the Bay Area to become infield coach for the San Francisco Giants on new manager Tony Vitello's staff.
A man convicted in the 2020 killing of a 19-year-old in San Francisco's Portola neighborhood will likely spend the rest of his life behind bars, prosecutors said.
A teenager who fired a gun during an after-school skirmish at Fairfield High School in September was already awaiting sentencing in a separate gun assault case at the time and will serve six months in detention for both cases, police said.
Two people suspected of stealing nearly $100,000 in items from a construction site in Napa County were arrested following dual pursuits early Thursday, police said.
The mother of a newborn baby who was found dead in Monterey County in 1994 has pleaded guilty to her son's death, prosecutors said.
One of two people charged in the Santa Rosa killing of Mark Calgani, the general manger of San Francisco's Condor Club, has pleaded no contest in the case.
European regulators said X breached transparency rules under the Digital Services Act, a sweeping EU law intended to protect internet users.
An alert sent to people across California warning about a strong earthquake striking Northern Nevada on Thursday morning was sent in error, officials said.
Bay Area technology giants were among the winners at the 76th Annual Technology and Engineering Emmy Awards in New York on Thursday.
Children and adolescents who own smartphones by age 12 have higher risks of depression, poor sleep and obesity, according to a new study.
AI is swiftly reshaping America's labor market, performing many technical and cognitive tasks across a range of industries, study says.
Officials in Monterey County have issued a warning to people foraging for wild mushrooms amid a rise in poisonings.
San Francisco officials said Tuesday that the city has filed a lawsuit against leading manufacturers of ultra-processed foods, accusing them of producing products linked to serious health issues and alleging that the companies knowingly made the foods addictive.
Consumers with the imported pans should throw them away due to the severe health risks posed by lead, the agency warns.
ByHeart said it can't rule out that all of its baby formula across all product lots could be contaminated, citing recent test results.
In an interview with CBS News, FDA Commissioner Dr. Marty Makary explains what went into the decision to drop the most serious warnings on hormone therapy for menopause.
The Supreme Court said Friday it will decide the legality of President Trump's executive order that seeks to end birthright citizenship.
Just a year after Alameda County District Attorney Pamela Price was recalled by nearly 63% of the voters, she's running again to get her job back.
Texas approved a new congressional map this summer after Trump urged state GOP lawmakers to craft new House district lines to help Republicans hold onto their majority in the 2026 midterms.
Authorities say the FBI has arrested a man suspected of placing pipe bombs outside RNC and DNC headquarters on the eve of the Jan. 6, 2021, Capitol riot.
Derrick Lew, who was born and raised in San Francisco, has been with the department for more than 20 years, and in that time, he has served at the Ingleside, Bayview, Mission and Central stations, the mayor's office said.
A 16-year FBI employee has filed a lawsuit alleging he was fired last month because he had a Pride flag displayed near his desk.
A group of transgender members of the U.S. Air Force and Space Force forced to leave active duty under the Trump administration's policies say their benefits were revoked in a rare move.
California state Sen. Scott Wiener of San Francisco announced Wednesday that he is running for Nancy Pelosi's congressional seat next year.
Advocacy group The Trevor Projected released data from the first year of a study following more than 1,600 LGBTQ+ youth across the country.
A former Yosemite employee says they've been fired by the National Park Service, three months after flying a transgender pride flag from El Capitan.
Frank Gehry was known for designing the Guggenheim Museum Bilbao in Spain and the Walt Disney Concert Hall in Los Angeles.
Netflix on Friday said it will acquire Warner Bros., including its film and television studios, HBO Max and HBO.
Families along Thompson Avenue, also known as Christmas Tree Lane, have decked out their porches and front lawns in time for the holidays.
Cirque du Soleil's return brings more than spectacle to San Francisco; it continues to fuel the local economy. Nightly performances draw thousands into the 2,500-seat Big Top near Oracle Park, boosting foot traffic and business in the Mission Bay neighborhood.
Allison Keaney, the first female CEO of the Cow Palace, one of California's biggest rodeo venues, said ticket sales jumped 61% this year, and women's rodeo, once an afterthought, is now ropin' in fans fast.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Hundreds gathered Friday night in Oakland for a tribute to coach John Beam and to celebrate his life. It was the first organized memorial for the coach since he was fatally shot on Nov. 13.
Laney College coach John Beam was killed in a shooting in Oakland in November.
After three years working in the tech industry, he’s packing up and heading back to Canada, choosing to leave the U.S. not because he has to, but because he feels he can no longer stay.
The $50 million donation to CSU East Bay in Hayward is the largest single donation in the school's history. Sooji Nam reports.
A plan to build a 25-story apartment complex at the site of the popular San Francisco Marina District Safeway is running into fierce opposition from local residents. Da Lin reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.