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Doctors said the drugs can help people lose unwanted pounds while retaining muscle.
Six years ago, a woman made headlines when the Transportation Security Administration seized thousands of dollars in cash from her while she traveled through the Pittsburgh International Airport.
An advanced life support ambulance is based at the Oakdale fire station, bringing hospital-level care to the area.
A Michigan man was sentenced to 20 to 40 years in prison after he set a Bensalem home on fire with several people inside in 2025, officials said.
Another blast of cold air, high winds, and light to moderate snow is on the way for Friday into the upcoming weekend.
An Ohio man considered a suspect in the disappearance of a 17-year-old girl from Indiana led investigators to her remains, the Hocking County Sheriff's Office announced this week.
Troopers found nearly two pounds of cocaine after a traffic stop on the Pennsylvania Turnpike, the Westmoreland County District Attorney's Office announced.
PTL hosts Heather Abraham and David Highfield discuss Pittsburgh culture, trending news and social media, food, sports, and more. Plus, a preview of what's to come on today's show.
Investigators have no proof that the missing mother of "Today" show host Savannah Guthrie is still alive but are holding out hope she is "still out there," the sheriff said.
After getting stuck on the railroad tracks, the truck was hit by a train and sent into the porch of a nearby home.
36-year-old Glenn Thomas was taken into custody as a joint investigation between several federal, state, and local agencies.
The man was taken to the hospital in critical condition.
The bipartisan "Bell-to-Bell" bill bars students from using their phones any time they're in school, not just during instructional periods.
A 34-year-old California man is wanted for ethnic intimidation and criminal mischief for destroying the flag outside of a Jewish family's home.
Thomas Maglicco was appointed the new mayor of McKeesport when Michael Cherepko retired after 14 years of service.
Ron is teaching us about Forecast-O, and we're catching up on Heather and Mikey's families.
Heather Abraham and Mikey Hood talk about today's topics.
While "The Pitt" is fiction, it highlights some very real things about Pittsburgh. It means real organizations are getting more exposure.
Stay on top of local weather with First Alert Meteorologist Ray Petelin's forecast!
A massive water main break closed part of Route 8 in Shaler Township on Thursday.
A Marshall Township woman is stuck in the Middle East amid the U.S. and Israel's war with Iran.
Multiple adults are now facing felony charges connected to what was found inside the building.
A U.S. Army soldier from Pennsylvania who was killed in a crash in North Carolina is being remembered for his "compassionate soul."
The annual KDKA Fish Fry Guide is back for Lent! Check our listings for a 2026 fish fry near you in Pittsburgh.
With festivities ramping up, safety officials are warning drivers not to get behind the wheel while impaired.
The U.S. is "accelerating, not decelerating" war on Iran, Hegseth says, as strikes intensify in the region and reach 1,000 miles away.
President Trump said he expects the bombing campaign to last four to five weeks, but "we have [the] capability to go far longer than that."
"Sadly, there will likely be more before it ends. That's the way it is. Likely be more," President Trump said after mentioning the three U.S. service members killed in the operation.
President Trump posted on social media that Iranian Supreme Leader Ayatollah Ali Khamenei had been killed after a massive U.S. and Israeli military operation Saturday.
Americans weighed in on how long a conflict with Iran might last and what Congress should do.
There are always deals to be had at places like Sam's Club and TJ Maxx, but there are ways to get even bigger discounts.
Ollie's Bargain Outlet in Greensburg has temporarily closed after the Pennsylvania Department of Agriculture found a rodent infestation this week.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
Each year, the American Customer Satisfaction Index releases its survey of supermarkets, and several Pittsburgh grocers got high marks.
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
VisAbility Pittsburgh is using technology to change the lives of people who are blind, teaching those with impaired vision or blindness how to do daily tasks and prepare for jobs.
Robert and Paul from Just Roll'd Up have rolled into the PTL kitchen to show us how to make and eat their latest creation!
A group of students at Point Park University decided that if they couldn’t find the perfect location for their movie, they’d build it!
It’s a dreary day outside, but Daisy has visions of Apples to Rainbows! She’s showing us around the uniquely Pittsburgh gift shop in Castle Shannon.
What’s the biggest annoyance from a passenger in your car? Backseat driving? Eating? Head in the rearview mirror? We’re sharing your responses with our Whatcha Think Wednesday question.
From freshly washed cars to air conditioning units to entire porches, dust is blanketing one Westmoreland County neighborhood.
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
The Woodland Hills school board has been a lightning rod of controversy since putting Superintendent Joe Maluchnik on administrative leave three months ago.
Almost suddenly, Allegheny County has seen a dramatic drop in the number of people dying.
News organizations in the Pittsburgh area are coming together to help each other survive.
Fish fries can be a quandary for people with heart and other medical issues.
With a measles outbreak in Pennsylvania, local health experts want to send a message to families.
Cracking down on the price of prescription drugs is a hefty task.
The advisory, issued on Saturday, affected thousands of customers in Allegheny and Washington counties.
Pennsylvania American Water said that a first round of testing came back negative and an update can be expected late Monday morning.
Registration for fans who want to attend the 2026 NFL Draft has officially opened.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
The United States wasted little time showing how potent its roster could be at the upcoming World Baseball Classic.
The Mars Area school board voted 7-2 on Tuesday to hire Zachary Benedek to replace Eric Kasperowicz as the high school football coach.
Marat Khusnutdinov and Casey Mittelstadt scored less than a minute apart early in the first period and the Boston Bruins held on for a 2-1 victory over the Pittsburgh Penguins on Tuesday night.
A fire chief says a fire at an Ohio hog farm complex has killed about 6,000 pigs and unleashed a large plume of smoke that could be seen for miles.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
The budget airline Breeze is launching a new nonstop route from Pittsburgh to Myrtle Beach this summer.
The lawsuit accuses Nippon of prioritizing revenue over worker safety.
West Virginia took a major step in the fight against child pornography Thursday, after the state filed a first lawsuit of its kind against Apple.
The countdown is on, as the NFL Draft comes to Pittsburgh and America turns 250 years old.
Hillary Knight, Megan Keller and Jack and Quinn Hughes made a surprise appearance during "Heated Rivalry" star Connor Storrie's opening monologue on "SNL."
The medical drama "The Pitt" has certainly put a lot of eyes on Pittsburgh, and while the stories are fiction, the show highlights some very real things about the city.
Streaming giant Netflix declined to match Paramount Skydance's $31 per share offer for Warner Bros. Discovery.
A Romanian court on Thursday rejected an appeal by American rapper Wiz Khalifa to annul his nine-month jail sentence handed down for drug possession.
There is new optimism on the North Shore that the Pittsburgh Post-Gazette may continue to publish under new ownership.
A man in Pittsburgh was arrested after jumping into the river to avoid officers during a chase, police said.
A Marshall Township woman is stuck in the Middle East amid the U.S. and Israel's war with Iran. KDKA's Barry Pintar has more.
Police say children were living in disturbing conditions inside a condemned building in Charleroi, Washington County. Multiple adults are now facing felony charges connected to what was found inside. KDKA-TV's Shelley Bortz reports.
Joe Namath was born in Beaver Falls, and growing up, he was a standout athlete in several sports -- baseball, basketball, and football.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
