
FDA approves gene-editing treatment for sickle cell disease
Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
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Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
An estimated one in eight women will develop breast cancer in their lifetime, killing on average 42,000 a year in the U.S. But what if a vaccine could significantly lower each woman's chance of ever getting it in the first place?
Pediatricians are seeing an increase in pediatric cases of respiratory viral infections and the flu, Allegheny Health Network says.
With all the food, drink, candy, and parties, it's easy to let go during the holidays, but it is avoidable while still enjoying it.
Casual dining chain faces another wrongful death suit related to its Charged Lemonade after cardiac arrest of Florida man.
The American Academy of Pediatrics is sounding the alarm on excessive noise that kids and teens are exposed to.
State Rep. Arvind Venkat's bills would help promote food safety at restaurants across the commonwealth.
It's the time of year when the trees go up, the lights get lit, and sadly, people get hurt.
Clementine Blackham needed a rare, life-saving bone marrow transplant which she eventually received.
The "Charmed" and "Beverly Hills, 90210" actor said she hopes to get into clinical trials as new treatments are developed but what drives her now is the desire "to prove" that she can work despite her cancer diagnosis.
The tests will be available from a federal stockpile starting in December, and schools can distribute them to students, families, staff and larger school communities.
Recalled Burn Boot Camp snacks were sold at locations run by gym franchises throughout the U.S.
FDA finds reasonable expectation of effectiveness for drug designed to keep bigger breeds around longer, biotech firm says.
It's inevitable that people get sick during the holidays -- but how long is it before you're out of the woods?
A local boutique donated hundreds of cardigans to the Metastatic Breast Cancer Center at Allegheny General Hospital.
The high school football season ends this week with six PIAA state championship games.
A truck smashed into a bridge in Mercer County, taking a chunk out of it.
Matthew Bartlebaugh, 29, pleaded guilty to third-degree murder and possession of an instrument of crime charges.
At least 100 public safety responders were called to a massive crash at the Liberty Tunnel on Thursday night.
Have you asked middle and high schoolers what they want to do for a job and they have no idea?
President Biden is announcing $8.2 billion in new federal funding for 10 passenger rail projects across the country.
Stream Around The Table segments here on CBS News Pittsburgh.
Hunter Biden, the son of President Joe Biden, was indicted in the Central District of California Thursday.
Pennsylvania Gov. Josh Shapiro is reviewing his first year in office.
It’s been nearly a year since Gov. Josh Shapiro took office, and in an exclusive interview with KDKA-TV political editor Jon Delano, the governor reflected on one particular issue in the commonwealth: crime.
PTL's Boaz Frankel heads to Fayette County for the grand opening of the very crowded Uniontown Grocery Outlet. He's been tasked with getting everything we need for a holiday get together!
Want to check the latest product recalls, click here!
When, who and how much to tip is becoming more of a question in consumers' minds.
KDKA's Jessica Guay has some of the hidden hazards inside some toys.
Tipping amounts were down last year, so is a rebound on the way? Just who should you tip and how much?
That's a wrap for this week on PTL!
Our PTL pup, Roberto stopped by the studio!
In this edition of the PTL Winter Wonderland Tour, Daisy Jade went to Oglebay Resort to check out the holiday lights that you're going to love!
Jack Dougherty was here from the Pittsburgh Downtown Partnership to tell us about all the fun stuff happening in downtown Pittsburgh, and there's a lot.
Boaz was live at Steel City Con and got to speak with 'A Christmas Story' star Peter Billingsley!
Some schools are exposing children to daily doses of lead-tainted water.
If you're in a wreck, going with the wrong tow truck driver may cost you or your insurance company a small fortune.
You're in a car accident and need a tow, but when you get the bill it's for thousands of dollars.
In a statement to KDKA-TV Investigates, the VA says it is now open to the use of psychedelics to treat PTSD.
Adam Zaffuto came home to Pittsburgh after tours of duty overseas, but the wars and their emotional scars came with him.
Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
An estimated one in eight women will develop breast cancer in their lifetime, killing on average 42,000 a year in the U.S. But what if a vaccine could significantly lower each woman's chance of ever getting it in the first place?
Pediatricians are seeing an increase in pediatric cases of respiratory viral infections and the flu, Allegheny Health Network says.
With all the food, drink, candy, and parties, it's easy to let go during the holidays, but it is avoidable while still enjoying it.
Casual dining chain faces another wrongful death suit related to its Charged Lemonade after cardiac arrest of Florida man.
The high school football season ends this week with six PIAA state championship games.
JuJu Smith-Schuster caught four passes for 90 yards in the New England Patriots' win over the Steelers at Acrisure Stadium.
Karns City quarterback Mason Martin is ready to restart rehab after battling multiple infections.
Vazquez was convicted on sexual assault charges with a minor in 2021.
Tonight, an old friend will be honored for a successful career, but remembering what he brought could help this team.
All of their chocolate is made fresh from scratch, mostly in their Canonsburg facility.
When, who and how much to tip is becoming more of a question in consumers' minds.
The Federal Railroad Administration has selected four routes serving Ohio and other states as priorities for Amtrak expansion.
Forecasts are showing our region could see a wintry mix Tuesday.
U.S. and Israeli authorities say the Municipal Water Authority of Aliquippa was just one of multiple organizations breached by Iran-affiliated hackers who targeted a specific industrial control device because it is Israeli-made.
Ryan O'Neal, the Oscar-nominated star of films including "Love Story" and "Paper Moon," has died at 82.
A star-studded lineup of hip hop legends and GRAMMY-winning artists will grace the stage at this special tribute concert, airing Sunday, Dec. 10 (8:30-10:30 PM, ET/8:00-10:00 PM, PT) on the CBS Television Network, and streaming on Paramount+.
Andrea Bocelli has released a statement on "health challenges" affecting his world-famous voice.
Journey and Def Leppard are coming to Pittsburgh next summer.
"Silver Bells" was written by an acclaimed composer who grew up in the Pittsburgh area.
Get the latest weather updates with First Alert Meteorologist Ray Petelin's forecast!
The rescue believes they were the result of a backyard breeder trying to sell puppies ahead of Christmas.
There's a good chance you've used PayPal or Venmo or some other type of payment app. But have you ever wondered how secure they are? KDKA-TV money editor Jon Delano looks into that in this week's "Money Minute".
A stretch of I-376 in Mercer County will be closed for a couple of days after a truck smashed into a bridge on Thursday.
At least 100 public safety responders were called to a massive crash at the Liberty Tunnel on Thursday night. Seven people were taken to the hospital after a nine-car crash. KDKA-TV's Erika Stanish has more.
The Steelers lost 21-18 to the 2-10 visitors from New England.
The Cardinals had dropped nine straight road games in a row before today's win in Pittsburgh.
Jaylen Warren and Najee Harris each rushed for a touchdown in the win.
The Steelers' defense came up big with a stand in the shadow of their end goal post late in the game.
Kenny Pickett left the game with an injury and Mitch Trubisky was unable to lead a comeback rally in the second half.