Pittsburgh-Based Company On Verge Of Breakthrough Drug For Alzheimer's Disease
Alzheimer's disease affects 44 million people worldwide, and the worry of a loved one getting it strikes fear in most of us.
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Alzheimer's disease affects 44 million people worldwide, and the worry of a loved one getting it strikes fear in most of us.
If the city's South Side neighborhood is your spot to eat, drink and party on the weekend, get ready for some changes come next year.
Police arrested a man who fired multiple shots into an apartment building Monday.
Police are stepping up patrols across the area on this night before the Thanksgiving holiday.
A man, considered by police to be armed and dangerous following his involvement in a shooting last week in Arlington Heights, is now in police custody.
Police are investigating after a man was shot three times in Arlington Heights Tuesday evening.
The steps of Pittsburgh have served generations of residents on the South Side Slopes. Now, one popular set of steps is getting a colorful facelift.
Pittsburgh Police are reaching out to the public after a series of what they say are increasingly violent business robberies in different city neighborhoods.
A man who was falsely arrested for assaulting a pregnant woman is now suing the City of Pittsburgh.
A couple of hundred bicyclists advocating for safer and more bike lanes on city streets gathered on the South Side Tuesday night.
Police arrested one man and continue to search for two more in connection to a robbery that took place on the South Side early Saturday morning.
Police are investigating a shooting that took place in the South Side early Saturday morning.
Firefighters are working to extinguish a blaze on the city's South Side.
A man accused of ramming his dump truck through the security gate at the FBI building in Pittsburgh won't appear in state court until later this month.
An Ohio man is facing federal charges after nearly crashing into a Pittsburgh Police motorcycle officer, running several red lights and then crashing through the security gates of the FBI building on the South Side.
A Pittsburgh police officer is being praised on social media after being "caught committing an act of kindness."
A local mother is accused of lashing out at police officers and other first responders after she was found passed out on a bench on the South Side with her child.
Crews with Norfolk Southern set off blasts on the hillside along West Carson Street early this morning to clear away loose rocks after a landslide last week.
The South Side had a patriotic look Thursday morning when bikers dressed in red, white and blue took off for the nation's capital on a mission called 335 Miles for Veterans.
Hillary Clinton Tuesday night attended a fundraiser hosted by Pittsburgh Steelers head coach Mike Tomlin and his wife.
Fresh off being named the presumptive Democratic presidential nominee, Hillary Clinton is campaigning in Pittsburgh Tuesday.
Roughly 20,000 fans watched Game 5 of the Stanley Cup Final on two big screens set up in Pittsburgh Thursday night.
The district attorney has dropped prostitution charges against a troubled Pittsburgh-area landlord, but expects to refile them after more investigation.
It has been decades since one of Pittsburgh's pro teams has had the chance to clinch a championship at home.
We all know the kind of celebration winning a sports championship can bring to a city.
Complete Streets spent nearly a full day in Oakland studying one of the biggest and most dangerous intersections in the city.
The 36-year-old man is accused of groping a woman wearing an Easter Bunny costume at the South Hills Village Mall.
Cooler air is coming in behind the rain and storms we had on Thursday.
The memorial service was held Thursday night at the Sutersville Primitive Methodist Church.
Ben Kindel scored the shootout winner to lead the Pittsburgh Penguins to a 4-3 win over the Ottawa Senators on Thursday night.
Complete Streets spent nearly a full day in Oakland studying one of the biggest and most dangerous intersections in the city.
The 36-year-old man is accused of groping a woman wearing an Easter Bunny costume at the South Hills Village Mall.
Cooler air is coming in behind the rain and storms we had on Thursday.
The annual KDKA Fish Fry Guide is back for Lent! Check our listings for a 2026 fish fry near you in Pittsburgh.
The memorial service was held Thursday night at the Sutersville Primitive Methodist Church.
Two Republican state senators have introduced a proposal to hold people accountable for evading tolls on the Pennsylvania Turnpike.
In a 54 to 37 vote, two Democrats voted with all Republicans in attendance to advance Sen. Markwayne Mullin's nomination. A final confirmation vote is expected in the coming days.
Most Republicans, especially MAGA, continue to support the US action and express a lot of confidence in Trump personally.
The Supreme Court will consider whether states can count mail ballots that are postmarked by Election Day but arrive after.
Robert Mueller served as FBI director from 2001 to 2013 and led the investigation into allegations of Russian meddling in the 2016 presidential election.
Studies show nearly 25% of Pennsylvanians can't pay their power bills at least once a year.
After a rat raised questions about health and safety at The Urban Tap, the owner says the South Side business is ready to gain back the public's trust.
Looking to get free shipping when you make an online purchase, but your order doesn't qualify? Here's how you can change that!
Pennsylvania farmers say economic factors like diesel fuel and fertilizer costs are pushing them to the edge.
The gas price spikes are real and apparent. Here's how Pittsburgh drivers can save money.
Spring is a natural reset point, and that can include your fitness! Mikey and David are joined by an old friend, Daniel Hill of House Call Training, who gives you some easy, at-home workouts to kickstart your spring!
Mikey and David are joined by Derek Rochna, the owner of The Farmer's Burger, a new burger truck in Pittsburgh!
With all the chaos at the airport recently, you may be tempted to cancel your flight, but there are some things you should check before you hit the cancel button!
A lot of us have some bad habits when it comes to booking flights, hotels, and trips, but travel expert Bobby Laurie is back on PTL to help you clean them up!
As a part of our spring cleaning series, we reveal who between Pittsburgh Today Live and Talk Pittsburgh had the most expired item in their cabinet, and Mikey and David take your questions in another Friday Free for All!
Steven Eason, 15, was shot and killed while trying to break up a fight at the Haunted Hills Hayride in North Versailles in 2021. No arrest has been made.
People in the Pittsburgh area formed "Families for Justice," a support group for parents who lost children to gun violence.
An inspection sheds light on why dust is blanketing a neighborhood in Westmoreland County.
The O'Connor administration will begin taking a scalpel to Pittsburgh's finances as it tries to close a $30 million to $40 million budget hole.
Residents in the area of Rochester, Beaver County, say a persistent chemical smell has taken over the air.
When doctors found out Ainsley Flynn had viral myocarditis, they leaped into action to save her. Now, Flynn is giving back.
UPMC Hillman Cancer Center is exploring everything radiation treatment can treat, and the success has been life-changing for people.
A Pittsburgh-area man is not just giving people living with ALS a voice, he's giving them their own voice.
A cancer once rare in young people has become the number one cause of cancer-related deaths for Americans under age 50.
Fish fries can be a quandary for people with heart and other medical issues.
Ben Kindel scored the shootout winner to lead the Pittsburgh Penguins to a 4-3 win over the Ottawa Senators on Thursday night.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
The Mets chased Paul Skenes in the first inning of his worst major league start, beating the Pirates 11-7 on Thursday.
Sidney Crosby left Thursday's Pittsburgh Penguins-Ottawa Senators game at the Canadian Tire Centre and did not return.
Paul Skenes didn't even get through the first inning on opening day.
Pittsburgh's newest music venue released a lineup of its first concerts on Monday, giving a taste of what's to come at Citizens Live at the Wylie.
Forbes' latest ranking of the world's richest people has been released, and the list features billionaires with ties to Pittsburgh.
A fire chief says a fire at an Ohio hog farm complex has killed about 6,000 pigs and unleashed a large plume of smoke that could be seen for miles.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
The budget airline Breeze is launching a new nonstop route from Pittsburgh to Myrtle Beach this summer.
Newborns at a Pittsburgh-area hospital dressed up to celebrate the 20th anniversary of "Hannah Montana."
11 shows will be coming to Pittsburgh, including six winners of the Best Musical at the Tony Awards.
CBS News announced Friday that CBS News Radio will be shutting down this spring after nearly 100 years of broadcasting, citing "challenging economic realities."
Chuck Norris' family said his death at 86 was sudden, but did not share any details on the cause.
A fast-casual restaurant and a massive plaza will be open on April 2 on Pittsburgh's North Shore.
Get the latest weather updates with meteorologist Ron Smiley’s forecast!
For 15 hours, a group of students sat down at the corner of Bates and Semple Streets in Pittsburgh's Oakland neighborhood to gather data for a traffic study. KDKA's Jessica Riley spoke with them about their objectives.
The driver was able to escape after their vehicle became submerged in flood waters in Cecil Township. KDKA's Chris Hoffman has the latest live from the scene.
Spring is a natural reset point, and that can include your fitness! Mikey and David are joined by an old friend, Daniel Hill of House Call Training, who gives you some easy, at-home workouts to kickstart your spring!
Mikey and David are joined by Derek Rochna, the owner of The Farmer's Burger, a new burger truck in Pittsburgh!
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.