FDA Approves New Obesity Drugs
Could the key to weight loss be in the brain? That's what drug makers are banking on with the FDA approval of new drugs designed to make you think you're full.
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Could the key to weight loss be in the brain? That's what drug makers are banking on with the FDA approval of new drugs designed to make you think you're full.
The national organization that manages organ transplants rejected making emergency rule changes Monday for children under 12 who are waiting on lungs, but created a special appeal and review system to hear such cases.
UPMC Amends the lawsuit they have filed against the city.
Many people have varicose veins and most people think they're just unsightly. However, they can also lead to serious problems and getting rid of them isn't always easy. Now, there's an easier solution to make your legs look and feel dramatically better.
Ten-year-old Sarah Murnaghan's desperately needs a lung transplant.
It is possible that a lot has changed since you learned CPR, and the people at the American Heart Association are using National CPR and AED Awareness Week to spread the word.
An organization that collects used medical equipment for the needy has moved from the East End, to Green Tree.
A 10-year-old girl in a Philadelphia hospital is waiting for a donor lung to save her life, and her parents are doing everything they can to get that lung.
Last summer, Sharon Herring-Turner had cancer removed from her breast, along with 25 lymph nodes under her arm.
It was a great morning for a walk.
UPMC Sports Medicine will host a Concussion Seminar where more than 400 health care professionals from around the world will converge at the Omni William Penn Hotel in Pittsburgh from June 6 through June 9.
Love conquers cancer. That's the crux of a new study which finds family and friends can help breast cancer patients physically feel better, especially when it comes to pain.
There's a new warning about raw milk. It could be contaminated with bacteria.
Niko Stevens loves playing with his big brother, Shawn. Niko is 3. He is autistic and doesn't speak.
Is your kid's sleep influenced more by their DNA or their surroundings?
The FBI says a growing online sextortion scheme is targeting people across the Pittsburgh area.
Two people are dead after a crash on Route 22 in Indiana County on Thursday, police said.
Figaretti's Restaurant in Wheeling, West Virginia, won a 2026 James Beard America's Classics award.
The annual KDKA Fish Fry Guide is back for Lent! Check our listings for a 2026 fish fry near you in Pittsburgh.
A Romanian court on Thursday rejected an appeal by American rapper Wiz Khalifa to annul his nine-month jail sentence handed down for drug possession.
From issues to races, a new Quinnipiac University poll out Wednesday took the pulse of Pennsylvania voters.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
Democrat Jen Mazzocco defeated Republican Joseph Leckenby for Pennsylvania's 42nd House District seat, the AP projects.
President Trump defended his first year back in office in his 2026 State of the Union address, touting his record on immigration, the economy, tariffs and more.
FedEx sued the Trump administration over its tariffs on Monday, asking for a "full refund" of all payments it made to the government under a set of tariff policies that were ruled illegal by the Supreme Court.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
Each year, the American Customer Satisfaction Index releases its survey of supermarkets, and several Pittsburgh grocers got high marks.
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
The budget airline Breeze is launching a new nonstop route from Pittsburgh to Myrtle Beach this summer.
Primanti Bros. is opening its doors early on Sunday as Team USA faces Team Canada in the gold medal game in men's hockey.
Pittsburgh Magazine's Sean Coiller is back giving his rundown of the best events you can check out in the city this weekend!
If you're looking for a can't-miss breakfast spot, look no further than Export and Wade's Breakfast & Grille. The owners, Alan and Karen joined Heather and David in the PTL Kitchen for a live demonstration of how they do breakfast!
February is American Heart Month, so we welcome Daniel Hill from House Call Personal Training to show us some heart-y exercises you can do right from the comfort of your own home.
Diner Week on PTL carries on today, and Daisy Jade is at the B&B Family Diner in Perryopolis where the portions are piled high!
They're calling it a relationship hack: When is the best time for couples to go to bed, and should they go to bed at the same time? Heather and David talk about that, as well as surprise our producer Maria!
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
The Woodland Hills school board has been a lightning rod of controversy since putting Superintendent Joe Maluchnik on administrative leave three months ago.
Almost suddenly, Allegheny County has seen a dramatic drop in the number of people dying.
News organizations in the Pittsburgh area are coming together to help each other survive.
It's no secret that many boroughs in the Mon Valley are riddled with abandoned and decaying homes.
Fish fries can be a quandary for people with heart and other medical issues.
With a measles outbreak in Pennsylvania, local health experts want to send a message to families.
Cracking down on the price of prescription drugs is a hefty task.
The advisory, issued on Saturday, affected thousands of customers in Allegheny and Washington counties.
Pennsylvania American Water said that a first round of testing came back negative and an update can be expected late Monday morning.
The team announced Crosby is expected to miss a minimum of four weeks with an injury.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
Drew Allar has recovered from ankle surgery and is expected to throw at the NFL's scouting combine this week.
The Penguins have traded defenseman Brett Kulak to the Colorado Avalanche for defenseman Samuel Girard and a second-round pick in the 2028 draft.
The school board voted 7-2 to move forward with the plan for synthetic turf fields.
A fire chief says a fire at an Ohio hog farm complex has killed about 6,000 pigs and unleashed a large plume of smoke that could be seen for miles.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
The budget airline Breeze is launching a new nonstop route from Pittsburgh to Myrtle Beach this summer.
The lawsuit accuses Nippon of prioritizing revenue over worker safety.
West Virginia took a major step in the fight against child pornography Thursday, after the state filed a first lawsuit of its kind against Apple.
A Romanian court on Thursday rejected an appeal by American rapper Wiz Khalifa to annul his nine-month jail sentence handed down for drug possession.
The Rock & Roll Hall of Fame has announced its 2026 list of nominees, including Phil Collins, Mariah Carey, Wu-Tang Clan and more.
Nick Reiner, 32, was charged with two counts of murder in the killing of his parents, Rob Reiner and Michele Singer Reiner.
"Jersey Shore" star Nicole "Snooki" Polizzi said in a TikTok video that her results at a post-op appointment for a cone biopsy showed stage 1 cervical cancer.
In April 2025, Eric Dane announced he had been diagnosed with amyotrophic lateral sclerosis, or ALS.
Food delivery drivers say they are losing money picking up in the Strip District due to parking tickets.
A man was sentenced to 3 to 6 months in jail for driving under the influence and killing an 11-year-old girl. KDKA's Jessica Riley spoke with lawyers from both sides to explain the sentencing.
As of next week, the United Steelworkers union will have a new top leader, as Roxanne brown will replace David McCall as the head of the 850,000-member union.
It's not everyday you are serenaded with the smooth sounds of the saxophone from the arms of a 7-foot SAXsquatch. Heather was today!
The FBI says a growing online scheme is targeting people across the Pittsburgh area.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.