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A Minnetonka toddler and her family got the incredible news that the "miracle drug" keeping her alive won't be discontinued after all.
Two people were injured after a crash involving a car and a Port Authority bus in Homewood.
A woman was taken to the hospital in stable condition after she was hit by gunfire in the North Side.
Duquesne University says the COVID-19 vaccine will be required for any students who want to participate in campus life next semester.
A Florida inmate who admitted he killed six people in Pennsylvania in the 1970s also discussed five to seven other slayings in the state, and police in those areas have been alerted, an investigator said Thursday.
The Allegheny County Health Department is reporting 33 new Coronavirus cases and no additional deaths.
The Pennsylvania Department of Health is reporting 656 new Coronavirus cases and 36 additional deaths.
Kidsburgh Ambassador Yu-Ling Behr has a list of local family-friendly events your kids will love in the month of June!
JWoww and Deena talk with us about fans can expect when the gang heads to the Poconos for a brand new season of "Jersey Shore Family Vacation."
West Virginia Governor Jim Justice announced the state's vaccination incentive lottery would now include custom hunting rifles.
It's the time of year that mice, chipmunks, and other critters begin emerging but while they may look cute, they can still do some damage.
Allegheny County has created a new department that focuses on children.
While the risk for severe weather in our area is marginal on Thursday, it cannot be ruled out.
A tractor-trailer crash has shut down east and westbound lanes of Interstate 70 near the New Stanton exit.
Pittsburgh International Airport and Allegiant are offering direct flights to Key West and Norfolk.
Homeowners flooded Allegheny County Council offices with calls on Wednesday, complaining about a plan for a major property tax hike. Some councilmembers say they just can't support an increase as large as the county executive wants. KDKA-TV's Andy Sheehan reports.
A massive entertainment, retail and housing development proposed on Pittsburgh's North Side is a step closer to happening.
Get the latest weather updates with First Alert Meteorologist Ray Petelin's forecast.
Hurricane Milton is on a path to make landfall late Wednesday night near Sarasota.
A Jeannette police officer was charged with 18 misdemeanor counts of tampering with public records for allegedly making several traffic stops that apparently never happened. KDKA-TV's Chris DeRose has more.
Allegheny County Common Pleas Judge Edward Borkowski refused to drop an attempted homicide charge against Jasper Hilliard.
A Westmoreland County man is facing charges after police say he allegedly stabbed a driver after a road rage attack on the Pennsylvania Turnpike.
The Forbes Trail Chapter of Trout Unlimited says there could be more trout in Linn Runn.
The Coast Guard says it will close parts of Pittsburgh's three rivers during the NFL draft later this month.
More than 300 pigeons were rescued from a hoarding situation in Pennsylvania, a wildlife rehabilitation center said.
First lady Melania Trump delivered a televised statement denying a relationship with the late sex offender Jeffrey Epstein.
Pittsburgh-area lawmakers are responding to President Trump's warning that "a whole civilization will die" if Iran doesn't make a deal to reopen the Strait of Hormuz by his 8 p.m. Eastern deadline. KDKA's Chris Hoffman reports.
Those who gathered on Tuesday said the push for drop boxes will continue.
President Trump posted on social media that "a whole civilization will die tonight," adding "but I don't want that to happen, but it probably will."
President Trump and top national security officials shed new light on the daring rescues of two American airmen who were shot down over Iran last week.
Six new cities are being added to the Michelin Guide in 2027, and among those cities is right here in Pittsburgh.
Sheetz is expanding further into the Midwest, with plans to open 100 stores in Indiana over the next decade.
The Pirates' home schedule starts on Friday, so how can fans save money on tickets, food, and other deals at PNC Park?
Fat Head's Saloon on Pittsburgh's South Side is closing next month after more than 30 years in business.
Studies show nearly 25% of Pennsylvanians can't pay their power bills at least once a year.
Just like he does every Thursday, Pittsburgh Magazine's Sean Collier joins the show to give us a rundown of the best events coming to the 'Burgh this weekend!
KDKA's Chris Hoffman has been on the NFL Draft beat for weeks now, and he's hosting KDKA-TV's streaming show, Draft Command, and he's giving us the rundown of what the city can expect.
Our friend Yu-Ling Behr from Kidsburgh is back on the show and she's giving us the springtime rundown of family fun!
They only last a couple of minutes, but they take an entire year to build! Team PTL's Daisy Jade is getting a firsthand look at the CMU Buggy Races!
Ron Smiley is back on PTL and while it may be a couple of days late, we celebrate him with a delicious cake and a round of Think, Thank, Thunk!
Allegheny County Common Pleas Judge Edward Borkowski refused to drop an attempted homicide charge against Jasper Hilliard.
Just weeks before the NFL draft, the Downtown Neighbors Alliance has cut ties with its executive director and may be folding up its tent.
Data obtained by KDKA Investigates shows the dramatic increase in arrests by U.S. Immigration and Customs Enforcement in the Pittsburgh area.
A new homeless encampment has popped up on Pittsburgh's North Side.
A Sewickley Hills man said he's left without a usable driveway because PennDOT cannot get it right.
UPMC and AHN say they've been collaborating about getting ready for an event of this magnitude.
When doctors found out Ainsley Flynn had viral myocarditis, they leaped into action to save her. Now, Flynn is giving back.
UPMC Hillman Cancer Center is exploring everything radiation treatment can treat, and the success has been life-changing for people.
A Pittsburgh-area man is not just giving people living with ALS a voice, he's giving them their own voice.
A cancer once rare in young people has become the number one cause of cancer-related deaths for Americans under age 50.
Pittsburgh Public Schools will be offering spaces throughout the city.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
The Pirates officially unveiled their 2026 City Connect jerseys, with a nod to Pittsburgh's "Sister Bridges."
Nick Castellanos hit a two-run double, Jake Cronenworth added a two-run homer and the San Diego Padres beat the Pittsburgh Pirates 8-2.
The 9th overall pick signed an extension that runs through the 2034 season.
Sheetz is expanding further into the Midwest, with plans to open 100 stores in Indiana over the next decade.
The event kicks off on April 22 with the reopening of the renovated Market Square.
Fat Head's Saloon on Pittsburgh's South Side is closing next month after more than 30 years in business.
Pittsburgh's newest music venue released a lineup of its first concerts on Monday, giving a taste of what's to come at Citizens Live at the Wylie.
Forbes' latest ranking of the world's richest people has been released, and the list features billionaires with ties to Pittsburgh.
Artists like Lady A, Nelly, The Avett Brothers and Third Eye Blind will headline a free concert series throughout Pennsylvania.
The Steelers will offer fans multiple ways to engage with the team during the NFL draft.
The event kicks off on April 22 with the reopening of the renovated Market Square.
A major music festival featuring the rapper formerly known as Kanye West was canceled after the U.K. government blocked Ye from entering the country.
Fred Rogers Productions and Little Dot Studios teamed up to bring the beloved children's show to YouTube.
Allegheny County Common Pleas Judge Edward Borkowski refused to drop an attempted homicide charge against Jasper Hilliard.
Linn Run is a pristine mountain stream that runs for several miles from Forbes State Forest and Linn Run State Park, down into the Loyalhanna Creek in Ligonier Township. And while there are trout in this stream, the Forbes Trail Chapter of Trout Unlimited says there could be more. Chris DeRose reports.
Linn Run is a pristine mountain stream that runs for several miles from Forbes State Forest and Linn Run State Park, down into the Loyalhanna Creek in Ligonier Township. And while there are trout in this stream, the Forbes Trail Chapter of Trout Unlimited says there could be more. Chris DeRose reports.
A Westmoreland County man is facing charges after police say he allegedly stabbed a driver after a road rage attack on the Pennsylvania Turnpike.
The Coast Guard says it will close parts of Pittsburgh's three rivers during the NFL draft later this month.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
