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Inside labs in Pittsburgh, researchers are cracking the code to save lives now and in the future.
A man was fatally shot Monday on Banksville Road.
West Virginia's governor has signed a bill that makes interfering with a police officer and causing their death a felony punishable by up to life in prison.
Some say it's a warning shot to hospitals across the commonwealth that do not pay property taxes.
The Justice Department alleged Rite Aid's Government Affairs department told employees to delete internal information warning about suspicious prescribers.
The coroner's office said it found "no evidence of trauma, foul play, abuse, or neglect."
Multiple people were transported to a hospital after a Pittsburgh EMS medic unit was involved in an accident.
A zebra attacked its owner at an Ohio home and bit the man's arm before it was fatally shot by a sheriff's deputy, authorities said.
The Fayette County District Attorney's Office is taking action against a Uniontown bar
Police say two men caught shoplifting at a grocery store in Georgia had an estimated $26,000 worth of baby formula in their car.
A potential plan is in the works that could impact some Catholic churches in East Pittsburgh communities.
Coming up on PTL! (3/13)
Pittsburgh Today Live's Heather Abraham and David Highfield talk about all the latest goings on and preview what's to come on today's show!
A man was shot and killed inside of a home in Clairton, Allegheny County police said.
Biden administration officials announced a series of emergency moves to reassure the public of the soundness of the financial system.
David Highfield and Heather Abraham talk about all the latest goings on and preview what's to come on today's show.
The crash happened in the inbound lanes of the highway just outside of the Squirrel Hill Tunnel.
The motto for search and rescue nationally is "so that others may live."
Get the latest weather forecast from KDKA First Alert Meteorologist Mary Ours!
The public comment period opens on Monday at 8 a.m. and there a number of ways people can give feedback to what PRT is proposing.
A fire in a void space between floors broke out early on Sunday morning at Ross Park Mall.
Whether it's unique events or just something that feels normal, kids diagnosed with cancer need normalcy, and that's what Lending Hearts provides.
A driver was going the wrong way on the Parkway West when they collided head-on with an SUV early on Sunday morning.
Sunday will be the last day of bitter cold as temperatures begin ticking up throughout the week.
The loss of the 18-year-old shook his friends on campus, who remembered him as the person who could always make them smile.
The footage is included in a video that promotes false claims that the 2020 presidential election was rigged against Mr. Trump.
The bipartisan "Bell-to-Bell" bill bars students from using their phones any time they're in school, not just during instructional periods.
It was only a few months ago that Pennsylvania passed the 2025 budget several months late, and now the process begins for this year.
Pennsylvania Gov. Shapiro delivered his fourth budget address at the State Capitol in Harrisburg, three months after last year's budget was passed by state lawmakers.
A federal judge on Monday blocked the Trump administration from revoking Temporary Protected Status for Haitians, granting a last-minute reprieve to 350,000 immigrants who were set to lose protections on Tuesday.
More than 90,000 customers are under a boil water notice due to an early morning power surge at a treatment plant.
A woman and her husband are fighting for a $400 refund after they bought furniture from a Value City Furniture store.
It's the end of an era for a grocery store in Carrick.
A Pennsylvania couple says Kia wrongly denied a warranty claim after their car's engine failed at 80,000 miles.
Scams targeting utility customers are on the rise in Pennsylvania, the attorney general says.
Daisy takes us live to learn more about 100.7 Star's Best Pizza in Pittsburgh competition.
We’re hearing from some of you! How did you meet? What is your love story?
Daisy shows us how to see our closet in a different way.
Some local pups will be in the game this year, and we’re meeting one from Animal Friends!
The band has a Pittsburgh connection, and we’re getting a performance live in the studio!
Residents of Millvale are trying to get back to normal after last weekend's major snowstorm.
Tracing the past of Shane Hennen and how his troubled life in Pittsburgh pointed to his future downfall.
People in Avella, Washington County, say they have no phone coverage.
Residents and leaders in Charleroi are concerned about the integrity of roads after a trench collapse last year and ongoing construction.
Patrick Vereb is accused of taking money from pet owners who believed their animals would receive dignified cremations.
More than 90,000 customers are under a boil water notice due to an early morning power surge at a treatment plant.
Doctors said the drugs can help people lose unwanted pounds while retaining muscle.
Southwestern Pennsylvania's cold and snowy winter is taking its toll on more than just our roadways and walkways.
The Liberty-Clairton area is under a code orange air quality action day, according to the Pa. Dept. of Environmental Protection.
The cold weather and lingering snow affect more than just the roads and our cars, it affects our brains.
Lindsey Vonn, who came out of retirement to compete in the Milano Cortina Games, is in stable condition after her crash.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
Bad Bunny is set to take the stage at halftime for the 2026 Super Bowl. Here's who else is performing at Super Bowl 60.
Prosecutors have dropped the most serious assault charge against Penn State hockey star Gavin McKenna.
A person familiar with the negotiations tells The Associated Press that pitcher José Urquidy and the Pittsburgh Pirates have agreed to a $1.5 million, one-year contract.
More than 140 employees at Nemacolin were informed they were being let go.
It's been about six years since the pandemic, and a lot of people working from home, but now companies are slowly calling them back to the office.
Pittsburgh Mayor Corey O'Connor on Tuesday announced a new initiative aimed at revitalizing neighborhood business districts across the city.
A handful of Pittsburgh-area Value City Furniture stores are going out of business after their parent company filed for bankruptcy.
It has been five years since the home improvement retailer Menards bought a large parcel of land off Route 30 in Westmoreland County.
Brad Arnold, the founder and lead singer of the 3 Doors Down has died following "his courageous battle with cancer," the rock band announced Saturday on social media.
Bad Bunny is set to take the stage at halftime for the 2026 Super Bowl. Here's who else is performing at Super Bowl 60.
Filming for the final season of "Mayor of Kingstown" is expected to take place between March and June.
Many Super Bowl 60 ads are already online, along with teasers for commercials that will be unveiled during the NFL championship on Feb. 8.
"Stick Season" singer Noah Kahan is coming to Pittsburgh this summer.
An early morning fire broke out at the Ross Park Mall and it took hours for crews to extinguish the flames.
Whether it's unique events or just something that feels normal, kids diagnosed with cancer need normalcy, and that's what Lending Hearts provides. KDKA's Megan Shinn shares their work in the KD Sunday Spotlight.
KDKA-TV's Cassidy Wood and the Pittsburgh Post-Gazette's Brian Batko discuss the sports topics of the day.
A driver is dead after an early morning, wrong-way crash on the Parkway West early on Sunday morning.
Stay on top of local weather with meteorologist Mary Ours’s forecast!
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
