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Scientists say they've taken a major step toward developing a "mosquito birth control" drug to curb the spread of diseases that kill hundreds of thousands of people every year.
A Great Dane delivered 19 puppies over the weekend at the Kingman Animal Hospital in Arizona.
Baseball fans will be heading to Arizona for spring training soon, and if you want to make the trip from Pittsburgh, there are plenty of affordable flights.
Randy Heiss wasn't going to let anything -- not even an international border -- stop him from fulfilling an 8-year-old girl's Christmas wishes.
A sheriff's deputy in northeastern Arizona used a stun gun to drive off a large cow after after he rescued a woman pinned to the ground by the mammal.
A registered sex offender jailed since last year has been charged in the kidnapping and killing of two Arizona girls who went missing in 2012 and 2014, authorities announced Saturday.
Two people are missing after two boats collided on the Colorado River along the California-Arizona border, fire officials said.
A tunnel that stretches from a former Kentucky Fried Chicken in Arizona all the way to a home in Mexico was discovered last week by investigators, who believe the secret passageway was used for drug smuggling.
An Arizona man who sold ammunition to the gunman in the deadliest mass shooting in modern U.S. history has been charged in Nevada with engaging in the business of making ammunition without a license.
A property dispute has gone viral after an Arizona homeowner was filmed calling police on a hiker he claimed had roamed onto his land.
According to police, the man tried to enter the girl's bathroom stall at a Phoenix area gas station and was confronted and killed by her father.
A Phoenix girl missing since 1994 has been found.
Vets believe the gator lost it in a fight with another gator and just like humans losing a limb, the injury affected his ability to do everyday things.
Authorities say a 92-year-old woman killed her 72-year-old son during a confrontation about her moving to an assisted living facility.
A woman almost stepped on a rattlesnake when she was out on a hike, but her golden retriever jumped in front of her -- and ended up getting bitten.
A potential relaxing day at the pool became a nightmare when the family found multiple rattlesnakes in the pool noodle.
An Arizona police report says the backup driver in an Uber autonomous SUV was streaming a television show on Hulu just before the vehicle struck and killed a pedestrian in March.
Four Mesa police officers are on administrative leave following an incident captured on video last month in which a suspect was punched several times.
Federal investigators say the autonomous Uber SUV that struck and killed an Arizona pedestrian in March spotted the woman about six seconds before hitting her, but didn't stop because emergency braking was disabled.
Uber is ending its operation of self-driving cars in Arizona more than two months after a woman was struck and killed by one of its vehicles.
A woman accused of sending an Arizona man 65,000 text message tried to explain her actions in a jailhouse interview Thursday.
A fatal accident involving a driver-less car has sidelined Uber vehicles here in Pittsburgh and across the nation, and now Mayor Bill Peduto is weighing in on when they might be back on the local roads.
Self-driving Uber vehicles will be taken off the road in Pittsburgh and several other cities in North America following a fatal crash.
Former Arizona sheriff Joe Arpaio has announced he plans to run for the U.S. Senate seat now held by Jeff Flake.
A spokesman says GOP Sen. Jeff Flake will not run for re-election in 2018.
A majority of Steelers fans want the team to move on from Aaron Rodgers and remain divided over the hiring of Mike McCarthy.
The New York Rangers rallied to defeat the Pittsburgh Penguins 3-2 on Saturday.
A federal grand jury has indicted a man illegally residing in Pittsburgh on several charges, authorities say.
President Trump posted on social media that Iranian Supreme Leader Ayatollah Ali Khamenei had been killed after a massive U.S. and Israeli military operation Saturday.
Americans weighed in on how long a conflict with Iran might last and what Congress should do.
A majority of Steelers fans want the team to move on from Aaron Rodgers and remain divided over the hiring of Mike McCarthy.
The New York Rangers rallied to defeat the Pittsburgh Penguins 3-2 on Saturday.
A federal grand jury has indicted a man illegally residing in Pittsburgh on several charges, authorities say.
The annual KDKA Fish Fry Guide is back for Lent! Check our listings for a 2026 fish fry near you in Pittsburgh.
President Trump posted on social media that Iranian Supreme Leader Ayatollah Ali Khamenei had been killed after a massive U.S. and Israeli military operation Saturday.
President Trump posted on social media that Iranian Supreme Leader Ayatollah Ali Khamenei had been killed after a massive U.S. and Israeli military operation Saturday.
Americans weighed in on how long a conflict with Iran might last and what Congress should do.
Early on Saturday, the U.S. and Israel launched a military operation in Iran, and Pennsylvania's elected officials have responded.
President Trump said that "heavy and pinpoint bombing" of Iran would "continue, uninterrupted throughout the week or, as long as necessary."
Pennsylvania Gov. Josh Shapiro slammed the Department of Homeland Security's plans to open immigration detention facilities in Berks and Schuylkill counties.
There are always deals to be had at places like Sam's Club and TJ Maxx, but there are ways to get even bigger discounts.
Ollie's Bargain Outlet in Greensburg has temporarily closed after the Pennsylvania Department of Agriculture found a rodent infestation this week.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
Each year, the American Customer Satisfaction Index releases its survey of supermarkets, and several Pittsburgh grocers got high marks.
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
We're checking back in with Daisy at the Polar Plunge where some of the people you will see at this year's Horror Realm Convention are taking the plunge for a good cause!
David and Heather find themselves in West Deer where they're visiting the Deer Creek Diner, the winner of PTL Diner Week, as voted on by the viewers!
This weekend, the documentary The Football Town, premieres and PTL sat down to talk with the producers and the Steelers about the film that highlights the game that means so much to Pittsburgh.
Team PTL's Daisy Jade is live at Acrisure Stadium where the Special Olympics of Western Pennsylvania is hosting its annual Polar Plunge!
The release of Scream 7 is today, and Mikey and David are having a lot of fun celebrating another chapter in the horror classic! They also take your questions, and much more!
Former patients of Dr. Carl Medgaus are running out of time to try to recover money for unfinished dental work.
The Woodland Hills school board has been a lightning rod of controversy since putting Superintendent Joe Maluchnik on administrative leave three months ago.
Almost suddenly, Allegheny County has seen a dramatic drop in the number of people dying.
News organizations in the Pittsburgh area are coming together to help each other survive.
It's no secret that many boroughs in the Mon Valley are riddled with abandoned and decaying homes.
Fish fries can be a quandary for people with heart and other medical issues.
With a measles outbreak in Pennsylvania, local health experts want to send a message to families.
Cracking down on the price of prescription drugs is a hefty task.
The advisory, issued on Saturday, affected thousands of customers in Allegheny and Washington counties.
Pennsylvania American Water said that a first round of testing came back negative and an update can be expected late Monday morning.
A majority of Steelers fans want the team to move on from Aaron Rodgers and remain divided over the hiring of Mike McCarthy.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
The New York Rangers rallied to defeat the Pittsburgh Penguins 3-2 on Saturday.
The 2028 Summer Games will feature squash for the first time, and Pittsburgh is a place Olympic hopefuls are gathering.
The Steelers are anticipating quicker clarity about their quarterback situation this time.
A fire chief says a fire at an Ohio hog farm complex has killed about 6,000 pigs and unleashed a large plume of smoke that could be seen for miles.
Lawmakers in Harrisburg are looking at bills to tackle dynamic pricing.
The budget airline Breeze is launching a new nonstop route from Pittsburgh to Myrtle Beach this summer.
The lawsuit accuses Nippon of prioritizing revenue over worker safety.
West Virginia took a major step in the fight against child pornography Thursday, after the state filed a first lawsuit of its kind against Apple.
The medical drama "The Pitt" has certainly put a lot of eyes on Pittsburgh, and while the stories are fiction, the show highlights some very real things about the city.
Streaming giant Netflix declined to match Paramount Skydance's $31 per share offer for Warner Bros. Discovery.
A Romanian court on Thursday rejected an appeal by American rapper Wiz Khalifa to annul his nine-month jail sentence handed down for drug possession.
The Rock & Roll Hall of Fame has announced its 2026 list of nominees, including Phil Collins, Mariah Carey, Wu-Tang Clan and more.
Nick Reiner, 32, was charged with two counts of murder in the killing of his parents, Rob Reiner and Michele Singer Reiner.
Protesters gathered across Pittsburgh on Saturday to voice their disagreement with the military operations in Iran. KDKA-TV's Ricky Sayer spoke with protesters and supporters of the military action.
Stay on top of local weather with First Alert Meteorologist Trey Fulbright's forecast!
Iranian Supreme Leader Ayatollah Ali Khamenei was killed after a massive U.S. and Israeli military operation Saturday, President Trump said. Meanwhile, the reactions to the strikes against Iran were mostly split along partisan lines among Pennsylvania's elected officials.
Watch as teams from Mt. Lebanon, New Castle, and Shady Side Academy high schools compete on this edition of KD Quiz!
Watch as teams from Mt. Lebanon, New Castle, and Shady Side Academy high schools compete on this edition of KD Quiz!
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
