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Willson Contreras and Christopher Morel hit solo home runs for the Cubs, but Contreras left in the sixth inning with an apparent leg injury. Contreras limped around the bases after his homer.
One of the cuts appears to pave the way for Teven Jenkins to start at right guard on the offensive line.
The team said the 77-year-old manager would skip the game on the recommendation of his doctors and would undergo further testing Wednesday.
The Cubs blew a lead and lost for the 41st time, more than any other big league team.
CBS 2's Matt Zahn caught up with Zane Navratil the top-ranked singles player, who's enjoying his newfound celebrity status.
Offensive coordinator Luke Getsy is also avoiding any knee-jerk reactions to the offense's performance in the team's final preseason game.
Semmelroth broke his back in several places but still finished his deployment in Afghanistan.
Jake McCarthy hit a tiebreaking double in the ninth inning and the Arizona Diamondbacks completed a three-game sweep of the struggling Chicago White Sox with a 3-2 victory Sunday.
Christian Yelich and Kolten Wong each homered for the second straight game and Garrett Mitchell drove in two runs with his first hit as a major leaguer, leading the Milwaukee Brewers over the Chicago Cubs 9-7 Sunday.
Justin Fields had a nightmarish visit to Cleveland as a rookie. This one couldn't have gone much better.
Sen. Amy Klobuchar on Thursday launched her campaign to be Minnesota's next governor, a surprise twist in the race for the top job in the state as it experiences an unprecedented immigration enforcement operation that's ignited a national debate.
Senate Democrats released their list of demands to reform immigration enforcement and fund the government Wednesday, with little time to avert a partial government shutdown.
Chicago Ald. Byron Sigcho-Lopez (25th) announced Wednesday he is running as an independent candidate for U.S. Rep. Jesus "Chuy" Garcia's seat in Congress.
Chicago Mayor Brandon Johnson headed to Washington, D.C., on Wednesday to speak at the National Press Club luncheon.
Suggesting Iran could suffer the same fate as Venezuela, Trump warns Tehran to negotiate a new nuclear agreement, or face "major destruction."
This week marks Identity Theft Awareness Week, and Illinois Comptroller Susana Mendoza emphasized some safety tips Monday for avoiding and dealing with identity theft.
A controversial data center in Naperville, Illinois, could be the cause to pack a city council meeting there on Tuesday night.
Police in the west Chicago suburb of Geneva are warning of a scam involving spoofed phone numbers.
Protesters on Tuesday were cranking up the heat on Peoples Gas over a recently proposed rate hike that would add an additional $10 to $11 a month to utility bills.
A lawsuit filed late last month took Chicago-based McDonald's to task over the McRib sandwich, calling its name a form of false advertising.
It has been nearly six years since the start of the COVID-19 pandemic, and one of the many questions doctors are still working to answer concerns the long-term effects.
Leaders from Cook County, the Illinois Department of Human Services, and the Greater Chicago Food Depository denounced changes to the Supplemental Nutrition Assistance Program on Wednesday.
The University of Chicago Medicine Comprehensive Cancer Center has received a grant from The Ralph Lauren Corporate Foundation for a new cancer center.
Chicago's Lurie Children's Hospital said Tuesday that it is no longer initiating gender-affirming medical treatment for minors.
Roughly 1.4 million fewer Americans have signed up for an Affordable Care Act plan as expiring tax breaks drive up premiums.
January may be the coldest time of the year, but Chicago is already looking forward to summer farmers' markets.
A development proposal issued this month calls for the replacement of a building housing a Giordiano's pizzeria in Chicago's Lakeview neighborhood with a new mixed-use building with 28 residential units.
United Airlines flight attendants picketed outside Chicago's Willis Tower Thursday morning as they fought for a new contract.
WSCR-AM, 670 The Score, will begin a simulcast on 104.3 FM next month.
Does the Chicago Bears' dramatic improvement this season, culminating in their first playoff run in five years, change the discussion about where they will build a new stadium?
In a full-page ad in the Wall Street Journal, Ye, the artist formerly known as Kanye West, revealed that the right frontal lobe of his brain was injured in a car accident 25 years ago.
Sales of tickets to NHL games jumped more than 20% after the hit HBO show debuted in the fall, according to ticket vendor.
Among the names missing when the 98th Academy Award nominations were announced were Ariana Grande, George Clooney, Paul Mescal, Denzel Washington, and anyone associated with "Wicked: For Good."
The nominees for the 98th annual Academy Awards were announced Thursday morning, and though "One Battle After Another," "Marty Supreme," "Frankenstein" and "Hamnet" were all nominated for plenty, it was "Sinners" that broke through with a record-smashing 16 nominations.
Prince Harry struck a combative tone as he testified in his lawsuit against the Daily Mail's publisher.
Sentencing for a former Sangamon County deputy, convicted in the killing of a woman who called 911 for help back in 2024, is scheduled for Thursday.
A woman died after one of two house fires that broke out on Chicago's South Side overnight.
Meteorologist Laura Bannon has the extended forecast.
Nursing communities in Joliet and Plainfield also held candlelight vigils Wednesday night in Pretti’s honor.
Wondering why your natural gas bill has spiked as of late? One watchdog says there are a few factors.
A woman died, and another was injured after two house fires that broke out on Chicago's Southwest Side overnight.
A 19-year-old man is accused of stabbing a pregnant woman 70 times and then setting her apartment on fire in west Downers Grove.
Sean Grayson was found guilty last October of second-degree murder for the shooting of Sonya Massey.
Two men were charged, and police said they tried to rob a Concealed Carry License holder early Tuesday morning in Chicago's Belmont Cragin neighborhood.
Sen. Amy Klobuchar on Thursday launched her campaign to be Minnesota's next governor, a surprise twist in the race for the top job in the state as it experiences an unprecedented immigration enforcement operation that's ignited a national debate.
The crash on June 7, 2024, killed 76-year-old Bernice Pawilan. The driver had a history of traffic offenses, and, in fact, wasn't supposed to be on the road at all.
A town hall meeting on Monday night addressed the concerns of residents paying higher water bills after being forced to use a private utility company.
As temperatures fell below zero in Chicago on Friday, tenants of a public housing complex in the East Garfield Park neighborhood said they were freezing inside their own homes due to insufficient heat.
Chicago is marking 30 years since it started its first citywide recycling program, which began with a problematic kickoff, and continues to lag behind other major cities in terms of performance.
More than a year before identical twin brothers stopped teaching at the Thornton Fractional School District, administrators were aware of allegations that one of them had been sexually assaulting a student.
Chicago led 101-87 on a layup by Jalen Smith with 7:14 to go. But the Pacers responded with an 18-4 run and Jay Huff's 3-pointer with 2 minutes left tied it at 105-all.
The coming season begins in June for the Bandits with their first home series in Rosemont.
Kirill Kaprizov scored the shootout winner as the Minnesota Wild defeated the Chicago Blackhawks 4-3.
The Blue Demons are experiencing a turnaround, especially at home, in Chris Holtmann's second season at the helm.
Tuesday marks 40 years since throngs of Chicagoans braved subzero wind chills to welcome home the Super Bowl champion Chicago Bears.
Chicago police on Wednesday issued a community alert about an attack and robbery that spilled from a CTA Red Line train onto a station platform this past weekend.
Two men were injured Wednesday morning in a fight involving gunfire outside a gas station in Cicero, Illinois.
A food and liquor store in a strip mall in Chicago's Portage Park neighborhood was targeted in a crash-and-grab burglary early Wednesday.
The Illinois Attorney General's office has charged a Chicago police officer with bribery and misconduct.
A Chicago man was sentenced to 20 years in prison last week for invading a home in Naperville while on probation.
