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The Food and Drug Administration announced Monday the removal of two monoclonal antibody treatments after evidence showed they're less effective against the Omicron variant.
COVID-19 cases and hospitalizations in Pennsylvania are declining, but health officials are warning it's too early to say the surge is over.
At-home COVID tests have become part of daily life for many people because of the highly contagious Omicron variant.
Pfizer and BioNTech have begun a clinical trial for their Omicron-specific COVID-19 vaccine candidate, they announced in a news release on Tuesday.
Pennsylvania's state prisons announced Monday they will not allow in-person visits for the coming month because their staff has been thinned by coronavirus infection.
As the pandemic drags on, a new sub-variant of Omicron is starting to show up. The World Health Organization reports it's on the rise in dozens of countries.
Pretty soon, N95 masks will be popping up in stores all over town.
Starting today, Washington Health System has updated its requirements for mask-wearing in its facilities.
Around two dozen Westmoreland County residents gathered to remember those who lost their lives to COVID-19.
Gov. Jim Justice questioned a bill moving through the Republican-led Legislature that would prohibit mask mandates in public schools.
A new study led by a pediatrician at UPMC Children's Hospital found that children can develop neurological symptoms from COVID.
Free COVID-19 testing is available through the Allegheny County Health Department today.
While the Farm Show returned to an in-person event, many still stayed home.
It's a question many are asking -- when do you take a PCR COVID-19 test versus taking a rapid test?
A Pennsylvania state representative wants employers to count natural immunity in place of a COVID-19 vaccine.
Some people said they are trying to order the tests, but the site says someone already used their address.
PTL's Mikey Hood talks with Dr. Timothy Law, the Senior Medical Director for Clinical Services at Highmark, about the threats the COVID-19 pandemic still poses, as well as the Delta and Omicron variants.
While free, at-home COVID tests are now available through USPS, some are experiencing issues ordering them.
COVID-19 hospitalizations are continuing to rise in Pennsylvania, though not as sharply as previous weeks.
Under criticism after weeks of shortages, President Joe Biden's administration is working to make COVID-19 rapid test kits more available and accessible to Americans by boosting supply and lowering costs.
West Virginia Gov. Jim Justice on Monday resumed his weekly briefings on the coronavirus, six days after he tested positive for COVID-19.
Masks will be mandatory again at North Allegheny starting Tuesday.
Pittsburgh Public Schools is closing two of its schools for about a week due to COVID-19 protocols.
Two dozen members of the West Virginia National Guard are being sent to support hospital staffing efforts as COVID-19 continues to ravage the state.
AHN is now requiring all patients and visitors to wear an N95, KN95, or a surgical mask while in its hospitals.
A group of students at Duquesne University has grown frustrated with the lack of heat in their apartment.
Police said a Harmar Township man shot at several homes overnight before setting his own house on fire.
You may have seen him in person or on social media, but Chris Guy's mission is simple: spread positivity.
Pennsylvania's two sitting senators, Republican Dave McCormick and Democrat John Fetterman, told CBS News they do not support a U.S. military takeover of Greenland.
Three people were killed in a multi-vehicle crash in Darke County, Ohio, on Friday morning.
A group of students at Duquesne University has grown frustrated with the lack of heat in their apartment.
Police said a Harmar Township man shot at several homes overnight before setting his own house on fire.
You may have seen him in person or on social media, but Chris Guy's mission is simple: spread positivity.
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Pennsylvania's two sitting senators, Republican Dave McCormick and Democrat John Fetterman, told CBS News they do not support a U.S. military takeover of Greenland.
The lawmakers posted a video in November that told military service members that they "must refuse illegal orders."
Five congressional Democrats say they have received inquiries from the DOJ after they appeared in a video urging members of the military not to follow "illegal orders" — a move the lawmakers allege is political intimidation.
The U.S. Supreme Court on Tuesday took on two cases challenging states that bar transgender athletes from participating on sports teams that align with their gender identities. One of them involves a student from West Virginia. Lauren Linder reports.
The Supreme Court heard two cases involving laws from Idaho and West Virginia that ban transgender athletes from participating in girls' and women's sports.
Scams targeting utility customers are on the rise in Pennsylvania, the attorney general says.
A handful of Pittsburgh-area Value City Furniture stores are going out of business after their parent company filed for bankruptcy.
It has been five years since the home improvement retailer Menards bought a large parcel of land off Route 30 in Westmoreland County.
If you get a ticket in the city of Pittsburgh, there could be a higher chance that instead of getting it on your car windshield, you're getting it in the mail.
Western Pennsylvania is grappling with a December that has been significantly colder than in years past.
Taking a look back at the best moments of the week on Pittsburgh Today Live!
Team PTL shares simple ways to find happiness with one go-to move!
Tony Ciotoli, from City Grows, shows us which plants can help purify spaces during the cold, stuffy winter months!
Fitness Trainer, Daniel Hill of House Call Personal Training, shows us some simple exercises to get your body moving!
Local content creator, Jimmy Big Muscles, channeled his “Nonna’s” Chicken Cotoletta for today’s recipe!
Some drivers in Pittsburgh are ignoring road closure signs in the South Side Flats, leaving residents exasperated.
A Westmoreland County taxidermist is under investigation by the Pennsylvania State Police.
Stray voltage from a nearby streetlight shocked Montana Mitchell and her dog, leaving the dog immobile.
Twin boys have been seen selling lemonade for long hours several times a week on street corners throughout Pittsburgh and the suburbs.
A woman says she and her dog were shocked while running in Pittsburgh's Strip District.
The yearly tradition marks the start of months of training for Pittsburgh Marathon participants.
Firefighters have a 62% higher risk of cancer, and this week, the New Castle Central Fire Station hosted pre-screenings.
Once the holidays are over, we often find ourselves in a funk, so how can we find ways to boost our mood?
A major expansion in women's health care is taking shape in Washington County.
Flu cases keep increasing, but at least one Pittsburgh-area emergency room doctor says not everyone needs to visit him.
Mike Tomlin's assistant coaches aren't expected to be retained by the team unless they are rehired by the new coach.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
Sidney Crosby scored one of Pittsburgh's three power-play goals and the Penguins beat the Philadelphia Flyers 6-3.
Former Robert Morris University basketball player Markeese Hastings is accused of taking bribes to throw games.
The Steelers have reportedly requested to interview three different defensive coordinators for their open head coaching position.
Pittsburgh Mayor Corey O'Connor on Tuesday announced a new initiative aimed at revitalizing neighborhood business districts across the city.
A handful of Pittsburgh-area Value City Furniture stores are going out of business after their parent company filed for bankruptcy.
It has been five years since the home improvement retailer Menards bought a large parcel of land off Route 30 in Westmoreland County.
The Macy's location at the Pittsburgh Mills Mall will be among the several closures.
With the Steelers hosting their first playoff game with fans in the building since 2018, a lot of revenue is expected to be made in the city.
Scott Adams, the cartoonist who created the "Dilbert" comic strip, has died at the age of 68, his first ex-wife revealed on Tuesday.
"The Pitt" won big at the Golden Globes on Sunday night.
The 2026 Golden Globes honored the standouts in both film and television from last year. See the full list of winners and nominees.
Here is everything you need to know about how to watch and stream the 2026 Golden Globes.
Bob Weir wrote or co-wrote and sang lead vocals on Grateful Dead classics including "Sugar Magnolia," "One More Saturday Night" and "Mexicali Blues."
A group of students at Duquesne University has grown frustrated with the lack of heat in their apartment.
Stay on top of local weather with First Alert Meteorologist Ray Petelin's forecast!
A Harmar Township man is facing a slew of charges after police said he shot at several homes overnight before setting his own house on fire.
You may have seen him in person or on social media, but Chris Guy's mission is simple: spread positivity.
Coraopolis has ended its partnership with U.S. Immigration and Customs Enforcement. Chilekasi Adele has more.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
