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After losing in week 2, the 49ers will look to bounce back against the Arizona Cardinals. San Francisco will face a must win as they can't afford to drop two in a row, especially with one coming at the hands of a division rival.
A 49ers fan was assaulted in the parking lot of Levi's Stadium following a fender bender after the team's home opener game against the Chicago Bears.
"You have a lead like that at home, there's no way you should lose that game," John Madden told the KCBS radio morning crew. "Turnovers and penalties will probably do it every time. When you have that lead at home and you have a pretty good defense and a pretty good running game, you have to be able to control that game."
It's hard to win when you play like the 49ers did Sunday Night. When you get called for 13 penalties and commit 4 turnovers its hard to win in the NFL. They still outplayed Chicago and had a chance late to win, but fell short.
For many 49er fans on Sunday, it was a long wait to get home after the team's regular-season home opener at Levi's Stadium as some fans that drove to the game faced hours of delays
Jay Cutler passed for three fourth-quarter touchdowns after much of Chicago's starting defense went down, and the Bears beat the San Francisco 49ers 28-20 Sunday night to spoil their Levi's Stadium debut.
California Lt. Gov. Gavin Newsom and his wife, Jennifer Siebel Newsom, issued a statement Sunday, denouncing the San Francisco 49ers' decision to continue to play defensive end Ray McDonald during an investigation into felony domestic violence charges.
Supervisor London Breed spoke to KPIX 5's Phil Matier on Sunday about her nonbinding resolution which calls for the 49ers to keep Ray McDonald from playing while an investigation of felony domestic violence charges against the star defensive end continues.
The Santa Clara County District Attorney's Office Friday postponed a court hearing on potential felony domestic violence charges against San Francisco 49ers player Ray McDonald as the investigation continues, the office reported.
San Francisco's first major league sports franchise will play its home opener in another city for the first time in 68 years, as the 49ers inaugurate the team's new home in Santa Clara Sunday.
The 49ers home opener at Levi's Stadium was one of the hottest tickets in the league when the tickets were printed, but it appears the amount people are willing to pay to see the first ever regular season game at the new Santa Clara stadium has dropped sharply.
It's only week 2 and both the 49ers and Bears are both less than 100% entering an important matchup. Outside of Anthony Davis all players are a question mark, so hopefully injuries will have a minimal effect on the outcome.
Moral character is a key factor the San Francisco 49ers consider in recruiting players, a top team official said Thursday, acknowledging the difficulty of accurately assessing how an athlete will ultimately behave on and off the field.
The San Francisco 49ers announced they have suspended radio broadcaster Ted Robinson for comments he made on domestic violence.
San Francisco Supervisors have unanimously adopted a resolution that takes the 49ers to task for allowing a team member, who's the focus of a domestic violence investigation to play in last Sunday's game.
Tony Vitello walked up the dugout stairs to meet with reporters about 15 minutes later than expected because of a team meeting that went longer than planned.
The bushes that surrounded global superstar Bad Bunny during his record-breaking Super Bowl halftime performance at Levi's Stadium were indeed people in costume, and three Bay Area friends participated together after answering a vague casting call.
The Detroit Tigers announced Tuesday that they signed Justin Verlander, a 42-year-old free agent, to a one-year, $13 million deal.
San Francisco 49ers defensive lineman Keion White was shot and injured early Monday morning in San Francisco, the team confirmed.
Puerto Rican superstar Bad Bunny, born Benito Antonio Martínez Ocasio, is one of the most-streamed artists on the planet.
Google and Pepsi were among the best ads of the Big Game, while Coinbase and ai.com got failing grades, according to one ranking.
When a fan ran onto the field during the Super Bowl, Patriots player Kyle Williams ran to track him down.
The 31-year-old Puerto Rican artist Bad Bunny took the stage on Sunday dressed in all white, donning a jersey with his last name, Ocasio, and the number 64.
The Seattle Seahawks defeated the New England Patriots Sunday to win the 2026 Super Bowl.
Police in San Francisco announced that a teenage suspect has been arrested in connection with a mass shooting in the Richmond District near Ocean Beach late last year.
Americans, not foreign exporters, shouldered nearly the costs from the Trump administration's tariffs last year, according to the New York Fed.
Schools in the San Francisco Unified School District were closed for a 4th straight day on Thursday, as the teachers' strike continues without a labor deal.
California Attorney General Rob Bonta said the focus of this investigation is to find out if the response violated state anti-discrimination and disability rights laws.
The Federal Trade Commission sent a letter to Tim Cook one day after President Trump circulated a report raising questions about Apple News' practices.
Police in San Francisco announced that a teenage suspect has been arrested in connection with a mass shooting in the Richmond District near Ocean Beach late last year.
Schools in the San Francisco Unified School District were closed for a 4th straight day on Thursday, as the teachers' strike continues without a labor deal.
Parents held a virtual roundtable to talk about the ongoing strike in the San Francisco Unified School District.
The California Highway Patrol has issued a Feather Alert for a missing woman last seen in San Francisco in January.
San Francisco schools will be closed for a fourth day on Thursday, said Laura Dudnick, San Francisco Unified School District director of communications.
A former member of the San Leandro City Council pled guilty in a corruption case that has ties to former Oakland Mayor Sheng Thao, federal prosecutors said.
The Alameda County Sheriff's Office said they received a call from a person claiming to have a firearm around 3:20 Monday morning. When deputies arrived, they say a person exited the home on Selborne Drive and presented an immediate threat to deputies. Two deputies shot at him, and he died from his injuries.
Some prospective tenants said they are still without housing and have been cut off from all help because they are officially listed in the county's computer as "permanently housed" at the Phoenix Apartments.
The legacy of the Black Panther Party, founded in Oakland in 1966 to protect the Black community while demanding freedom and justice, lives on through an award-winning walking tour.
A man who was arrested for allegedly refusing to leave an East Bay casino later died in custody after experiencing an unknown medical emergency, police said.
A San Jose shop owner has discovered that for the unhoused, a bicycle isn't just a reliable way of getting around; it can be a lifeline for a fresh start.
An assistant principal at a San Jose middle school was among a group of people arrested during a police operation targeting adults seeking minors online to engage in sexual activity, authorities announced on Wednesday.
Authorities on the Central Coast have recovered a body after a car plunged several hundred feet off Highway 1 in Big Sur Tuesday afternoon.
Authorities in Monterey County have arrested a man on suspicion of attempted murder after he allegedly stabbed a woman while driving on Highway 101 in Salinas over the weekend.
According to the DOJ, Tillman said he set fire to the U.S. Post Office in San Jose to "make a point to the United States Government."
A Sonoma County man has been arrested on multiple weapons charges after police seized more than 150 firearms from two homes as part of an investigation into the illegal manufacturing of guns.
One of the suggestions is the complete renovation of the Canal District shoreline, removing about 550 existing homes and raising the land high enough to safely redevelop on top of it. It is projected to cost nearly $2 billion.
A bank employee was among three people arrested in a series of armed home invasion robberies in Marin County of people who had withdrawn large amounts of cash, authorities said.
A man who was arrested on child sexual abuse charges in Illinois is facing additional charges in the San Francisco Bay Area in connection with the alleged sexual assault of a child, police said.
Four suspects remain at large and two were arrested after an armed robbery at a Petaluma jewelry store on Saturday, police said.
Tony Vitello walked up the dugout stairs to meet with reporters about 15 minutes later than expected because of a team meeting that went longer than planned.
The bushes that surrounded global superstar Bad Bunny during his record-breaking Super Bowl halftime performance at Levi's Stadium were indeed people in costume, and three Bay Area friends participated together after answering a vague casting call.
The Detroit Tigers announced Tuesday that they signed Justin Verlander, a 42-year-old free agent, to a one-year, $13 million deal.
San Francisco 49ers defensive lineman Keion White was shot and injured early Monday morning in San Francisco, the team confirmed.
Puerto Rican superstar Bad Bunny, born Benito Antonio Martínez Ocasio, is one of the most-streamed artists on the planet.
Police in San Francisco announced that a teenage suspect has been arrested in connection with a mass shooting in the Richmond District near Ocean Beach late last year.
A former member of the San Leandro City Council pled guilty in a corruption case that has ties to former Oakland Mayor Sheng Thao, federal prosecutors said.
Border czar Tom Homan announced Thursday that Operation Metro Surge in Minnesota is concluding, with a drawdown of federal immigration officers set to occur over the course of next week.
The California Highway Patrol has issued a Feather Alert for a missing woman last seen in San Francisco in January.
A Sonoma County man has been arrested on multiple weapons charges after police seized more than 150 firearms from two homes as part of an investigation into the illegal manufacturing of guns.
The Federal Trade Commission sent a letter to Tim Cook one day after President Trump circulated a report raising questions about Apple News' practices.
The family believes the outcome of the trial can lead to significant changes within the social media industry and help other families become even more aware of what they say are deadly devices in the hands of children.
The social media platform changed its privacy policy last month, inviting users to allow it to track their specific location.
Instagram's parent company Meta and Google's YouTube dispute claims that their platforms deliberately addict and harm children.
ChatGPT will clearly distinguish between ads and answers to user prompts on the AI platform, according to OpenAI.
Health officials in the East Bay said a man has died from consuming toxic wild mushrooms, amid an ongoing spike in mushroom-related poisonings throughout California.
Health officials in Napa County confirmed Wednesday that a child has been diagnosed with measles in the county's first case in nearly 15 years.
Over the years, Dr. Rachel Forer has found plenty of ways to take the sting out of going to the dentist. But no matter how hard she tried, fear had a way of creeping in.
Officials in San Mateo County are the latest in the Bay Area to warn residents to not forage for wild mushrooms, amid a rise in mushroom poisonings that have led to illnesses and even deaths.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
A former member of the San Leandro City Council pled guilty in a corruption case that has ties to former Oakland Mayor Sheng Thao, federal prosecutors said.
Border czar Tom Homan announced Thursday that Operation Metro Surge in Minnesota is concluding, with a drawdown of federal immigration officers set to occur over the course of next week.
Vilma Palacios is one of thousands who have given up their immigration cases and voluntarily left the U.S. after being detained. More detainees are opting for voluntary departure than ever before, a CBS News analysis found.
With so many candidates and no clear frontrunner in California's governor's race, two Republicans now lead in the polls in this heavily Democratic state, raising the question: Could the primary election lead to a Republican-versus-Republican runoff?
Pentagon officials had undertaken planning to use military technology near Fort Bliss, in El Paso, to practice downing drones.
After more than two years of renovations, the historic Castro Theatre is back open for business.
A large Pride flag has been removed from the Stonewall National Monument in Greenwich Village. The National Park Service said it did so under guidance from the federal government.
The billionaire and philanthropist MacKenzie Scott donated $45 million to The Trevor Project, a nonprofit focused on suicide prevention and advocacy for LGBTQ young people.
Oasis nightclub announced plans to close six months ago. New Year's Eve was slated for the final performance. A last-minute, multi-million dollar donation turned the final curtain call into an encore performance.
A 16-year FBI employee has filed a lawsuit alleging he was fired last month because he had a Pride flag displayed near his desk.
"Dawson's Creek" and "Varsity Blues" star James Van Der Beek has died at 48 years old.
After more than two years of renovations, the historic Castro Theatre is back open for business.
The bushes that surrounded global superstar Bad Bunny during his record-breaking Super Bowl halftime performance at Levi's Stadium were indeed people in costume, and three Bay Area friends participated together after answering a vague casting call.
The show unfolded as a visual journey through Puerto Rico's history, culture and identity, reaching an estimated 135 million viewers worldwide.
Puerto Rican superstar Bad Bunny, born Benito Antonio Martínez Ocasio, is one of the most-streamed artists on the planet.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Teachers in the San Francisco Unified School District and United Educators of San Francisco president Cassondra Curiel hold a briefing Thursday morning as a strike with the district entered its fourth day.
Expect showers to taper off Thursday, with clear conditions on Friday. Beginning on Sunday, a wet weather pattern returns, with heavy rain possible by the middle of next week. Jessica Burch has the forecast.
Lauren Toms reports on an entheogenic church in Oakland. Website: http://kpix.com/ YouTube: http://www.youtube.com/CBSSanFrancisco Facebook: https://www.facebook.com/CBSSanFrancisco Instagram: https://www.instagram.com/kpixtv/ Twitter: https://twitter.com/KPIXtv
Andrea Nakano reports on the teachers’ strike in San Francisco. Website: http://kpix.com/ YouTube: http://www.youtube.com/CBSSanFrancisco Facebook: https://www.facebook.com/CBSSanFrancisco Instagram: https://www.instagram.com/kpixtv/ Twitter: https://twitter.com/KPIXtv
Kenny Choi reports on a lawsuit against social media apps. Website: http://kpix.com/ YouTube: http://www.youtube.com/CBSSanFrancisco Facebook: https://www.facebook.com/CBSSanFrancisco Instagram: https://www.instagram.com/kpixtv/ Twitter: https://twitter.com/KPIXtv
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
