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Jimmy Garoppolo threw a touchdown pass on his first full drive after replacing an injured Trey Lance and ran for another score to help the 49ers beat the Seahawks 27-7 on Sunday.
The offseason story for the Seattle Seahawks and San Francisco 49ers focused on the change at quarterback.
The San Francisco 49ers lost more than a game in a sloppy season-opener at Chicago. The Niners lost starting running back Elijah Mitchell to a knee injury,
Trey Lance got the keys to San Francisco's offense in July. When it comes to driving in the rain, well, that still needs some work.
The Trey Lance era with the San Francisco 49ers got off to a soggy start Sunday as a weather system moved into the Chicago area bringing with it drenching downpours and a flash flood warning.
49ers star tight end George Kittle missed his second straight practice with a groin injury, leaving his status for the season opener against the Bears in doubt.
The 49ers advanced to the NFC championship game last season and they believe they have the playmakers to make another big playoff run.
Kyle Shanahan knows what the talk will be around the San Francisco 49ers if quarterback Trey Lance struggles in his first season as the starter with Jimmy Garoppolo waiting on the bench.
Before the news about Jimmy Garoppolo staying in San Francisco as the backup quarterback became public last week, 49ers coach Kyle Shanahan gathered a group of his team leaders in his office to explain the situation.
Jimmy Garoppolo moved over one field, rejoined his San Francisco 49ers teammates at practice for the first time since last season and was firing off passes the same way he always has.
General manager John Lynch broached the idea a few weeks ago with coach Kyle Shanahan about keeping Jimmy Garoppolo in place as the backup quarterback for the San Francisco 49ers.
The San Francisco 49ers and quarterback Jimmy Garoppolo have reportedly agreed to a restructured contract that would keep him on the team this season.
Athlete and activist Colin Kaepernick and his partner Nessa Diab announced Sunday the birth of their first child.
The clock continued to wind down Monday on decision day for the San Francisco 49ers and the future of former starting quarterback Jimmy Garoppolo.
The Houston Texans beat the San Francisco 49ers 17-0 on Thursday night in the preseason finale for both teams.
Jimmy Butler had 32 points and eight rebounds, Stephen Curry warmed up in the second half to finish with 27 points and seven assists, and the Golden State Warriors beat the New York Knicks 126-113 on Thursday night.
Seahawks QB Sam Darnold injured his left oblique during Thursday's practice and was listed as questionable for Saturday's NFC divisional playoff game against the 49ers, but he said he's confident he'll play.
San Francisco's star linebacker Fred Warner is out for the 49ers' playoff game against Seattle.
FIFA says it has received over 500 million ticket requests for 2026 World Cup matches in the U.S., Canada and Mexico— with prices as high as $8,680.
Head coach Kyle Shanahan stated that the goal is for Warner to return "next week," referencing a potential NFC Championship Game if the 49ers were to advance past the Seattle Seahawks on Saturday.
The U.S. Trademark Office is rejecting the A's request to trademark the "Sacramento Athletics" name.
Tomas Hertl had two goals and three assists, Jack Eichel also scored twice and the Vegas Golden Knights beat San Jose 7-2 on Sunday night, ending young Sharks star Macklin Celebrini's points streak at 13 games.
Nickeil Alexander-Walker scored 24 points, Jalen Johnson contributed 23 points, 11 rebounds and six assists and the Atlanta Hawks beat the Golden State Warriors 124-111.
The Eagles were eliminated from the playoffs in a 23-19 loss to the 49ers in the wild-card round of the NFL playoffs Sunday at Lincoln Financial Field.
The Oakland Police Department took a step toward addressing what city leaders described as a staffing crisis. On Friday, 14 new officers graduated from the department's 195th Police Academy.
A man suspected in a series of cold case sexual assaults in California and Texas was arrested this week near Houston, authorities announced Friday.
A man suspected in a crime spree involving more than 100 auto break-ins at four housing complexes in San Jose has been arrested, police said Friday.
"It's as definitive as we're going to get," CBS News medical contributor Dr. Céline Gounder said of the new research, which found no connection between Tylenol and autism or ADHD.
The suspect in the kidnapping and sexual assault of a teenage girl in San Jose was identified as a registered sex offender, police announced on Friday.
Prosecutors in San Mateo County said the driver involved in a fatal crash that killed a 4-year-old boy in Burlingame last year will not be charged in the case.
The Blue Angels made a visit to the Bay Area to as part of preparations for their show at San Francisco Fleet Week later this year, after last year's show was cancelled due to a government shutdown.
Officials in San Mateo County are the latest in the Bay Area to warn residents to not forage for wild mushrooms, amid a rise in mushroom poisonings that have led to illnesses and even deaths.
A man was convicted of involuntary manslaughter and acquitted of murder in the 2021 killing of Vicha Ratanapakdee, an 84-year-old San Francisco man killed in an unprovoked attack that helped galvanize a national anti-Asian hate movement.
The new name will apply to Music Concourse Drive between JFK Promenade and Martin Luther King Jr. Drive, directly adjacent to the Academy of Sciences, where Claude welcomed millions of guests during his 17 years at the museum.
The Oakland Police Department took a step toward addressing what city leaders described as a staffing crisis. On Friday, 14 new officers graduated from the department's 195th Police Academy.
A man suspected in a series of cold case sexual assaults in California and Texas was arrested this week near Houston, authorities announced Friday.
The NTSB released an initial report on the explosion and fire that destroyed a home near Hayward last month, but is still analyzing the handling of the response to a gas leak before the explosion.
A homicide suspect accused of a deadly shooting in San Pablo has been arrested after nearly a year on the run, officials said.
Three people were arrested Thursday afternoon following a helicopter-tracked pursuit tied to a shooting investigation in Oakland, police said.
A man suspected in a crime spree involving more than 100 auto break-ins at four housing complexes in San Jose has been arrested, police said Friday.
The suspect in the kidnapping and sexual assault of a teenage girl in San Jose was identified as a registered sex offender, police announced on Friday.
From the California coast, you can see a lot of surfers. It's not so easy to see a blue whale. However, at UC Santa Cruz, you can walk right up to a legendary blue whale, or at least its skeleton.
A wayward sea lion pup is now in the care of the Marine Mammal Center after it wandered into Mountain View last week.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
A man serving life in prison for a deadly gang shooting in Southern California has died following an altercation with another inmate at a prison in Solano County, officials said.
One Clearlake family said, considering how long it took to stop the leak, they don't have a lot of faith in the district, and that when the cleanup is completed, they will be hiring an independent company to test the neighborhood wells before using the water again.
San Rafael plans to build a shelter for people who are homeless, about 70 small cabins, using a Housing First approach. The model is built on the idea that for people living on the streets and battling addiction, it's hard to get sober without a place to live.
Residents say that what could replace an empty office building, which sits off the 101 Freeway in San Rafael at 700 Irwin Street, will worsen already heavily congested traffic.
Jimmy Butler had 32 points and eight rebounds, Stephen Curry warmed up in the second half to finish with 27 points and seven assists, and the Golden State Warriors beat the New York Knicks 126-113 on Thursday night.
Seahawks QB Sam Darnold injured his left oblique during Thursday's practice and was listed as questionable for Saturday's NFC divisional playoff game against the 49ers, but he said he's confident he'll play.
San Francisco's star linebacker Fred Warner is out for the 49ers' playoff game against Seattle.
FIFA says it has received over 500 million ticket requests for 2026 World Cup matches in the U.S., Canada and Mexico— with prices as high as $8,680.
Head coach Kyle Shanahan stated that the goal is for Warner to return "next week," referencing a potential NFC Championship Game if the 49ers were to advance past the Seattle Seahawks on Saturday.
A man suspected in a series of cold case sexual assaults in California and Texas was arrested this week near Houston, authorities announced Friday.
A man suspected in a crime spree involving more than 100 auto break-ins at four housing complexes in San Jose has been arrested, police said Friday.
The suspect in the kidnapping and sexual assault of a teenage girl in San Jose was identified as a registered sex offender, police announced on Friday.
Prosecutors in San Mateo County said the driver involved in a fatal crash that killed a 4-year-old boy in Burlingame last year will not be charged in the case.
A homicide suspect accused of a deadly shooting in San Pablo has been arrested after nearly a year on the run, officials said.
Verizon says it's giving a $20 credit to customers affected an outage that disrupted service across the U.S.
Grok faces mounting scrutiny from government officials and advocacy groups after people used the AI chatbot to create sexualized images of minors and women.
Mother of Colorado man who committed suicide in 2025 alleges that OpenAI's AI chatbot told him death was a "beautiful place."
Defense Secretary Pete Hegseth says the Pentagon will start using Elon Musk's AI chatbot Grok. The word comes days after Grok drew global outcry for generating highly sexualized deepfake images.
Kaiser Permanente has reached a lawsuit settlement over alleged patient data breaches involving Kaiser websites and mobile applications, with members eligible to receive a payment from a $46 million settlement fund, the health care giant announced.
Officials in San Mateo County are the latest in the Bay Area to warn residents to not forage for wild mushrooms, amid a rise in mushroom poisonings that have led to illnesses and even deaths.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
Kaiser Permanente has reached a lawsuit settlement over alleged patient data breaches involving Kaiser websites and mobile applications, with members eligible to receive a payment from a $46 million settlement fund, the health care giant announced.
Several East Bay hospitals that serve Alameda County's most vulnerable residents have issued layoff notices to staff, citing major federal cuts to Medicaid that administrators say will significantly affect their finances.
Officials said there were 35 cases of wild mushroom poisoning across California between Nov. 18 and Jan. 4. In an average year, fewer than five cases of wild mushroom poisoning occur statewide, according to Sonoma County health officials.
Mexican president Claudia Sheinbaum has sought to placate President Trump and build a strong relationship between the U.S. and Mexico.
The number of ICE detainees exceeded 70,000 for the first time in the deportation agency's 23-year history, according to internal DHS data obtained by CBS News.
The Justice Department says it also added about 80 more attorneys this week to help review the Epstein files to be released.
A construction controversy is building over the massive Sites Reservoir that could help solve California's water-storage problem.
President Trump is threatening to invoke a centuries-old law to deploy troops to Minnesota. Here's what to know.
The billionaire and philanthropist MacKenzie Scott donated $45 million to The Trevor Project, a nonprofit focused on suicide prevention and advocacy for LGBTQ young people.
Oasis nightclub announced plans to close six months ago. New Year's Eve was slated for the final performance. A last-minute, multi-million dollar donation turned the final curtain call into an encore performance.
A 16-year FBI employee has filed a lawsuit alleging he was fired last month because he had a Pride flag displayed near his desk.
A group of transgender members of the U.S. Air Force and Space Force forced to leave active duty under the Trump administration's policies say their benefits were revoked in a rare move.
California state Sen. Scott Wiener of San Francisco announced Wednesday that he is running for Nancy Pelosi's congressional seat next year.
The livestream unfolded with his team from LaRussell's garage, where he connected with fans through Instagram Live. During the broadcast, one woman shared that she was facing eviction. LaRussell covered the exact amount she needed to remain in her home.
Scott Adams, the cartoonist who created the "Dilbert" comic strip, has died at the age of 68, his first ex-wife revealed on Tuesday.
From historic wins to powerful speeches, here are the highlights and most memorable moments from the 2026 Golden Globes.
Here is everything you need to know about how to watch and stream the 2026 Golden Globes.
The San Francisco Grateful Dead community is coming together after it was announced that one of the founding members, Bob Weir, has died at the age of 78.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Friday's graduation of new Oakland police officers was the department's first in a full year. Da Lin reports.
Gov. Gavin Newsom joined San Francisco Mayor Daniel Lurie on Friday to announce $419 million in grant money as part of the state's homeless housing, assistance and prevention program. Brad Hamilton reports.
After a slow start to the winter season, skiers and snowboarders are now rushing to get the gear they need before heading to the slopes. Kara St. Cyr reports.
The 49ers fanbase has earned the reputation as football's "road invaders" for how they show up at opposing teams' stadiums. Kevin Ko sits down with a member of the Faithful who helps take tailgates on the road.
49er fans are letting their true colors show in the heart of enemy territory in Seattle. Ryan Yamamoto reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
