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The injury carts rolled out twice in three plays and the 49ers lost a few more key players. Still, short-handed San Francisco had enough to beat the inept New York Jets. And it wasn't even close.
The San Francisco 49ers will be without All-Pro tight end George Kittle this week because of a sprained left knee.
DeAndre Hopkins had a career-high 14 catches for 151 yards in his Arizona debut and set up Kenyan Drake's 1-yard TD run with 5:03 to play that led the Cardinals over the San Francisco 49ers 24-20 on Sunday.
San Francisco coach Kyle Shanahan remains hopeful the 49ers will be able to play their season opener against Arizona as scheduled despite poor air quality caused by wildfires in Northern California.
Arik Armstead sat down at the podium and had a message before he would answer any questions about playing defensive end for the San Francisco 49ers.
Madden NFL players will have the opportunity to see how Colin Kaepernick might fare if he was back on the field.
The San Francisco 49ers placed starting middle linebacker Fred Warner on the reserve/COVID-19 list Monday, less than two weeks before the start of the season.
San Francisco 49ers receiver Jalen Hurd went down with a knee injury that likely will sideline him for the season.
Nick Bosa said he hasn't been able to watch the fourth quarter of the Super Bowl even once. Jimmie Ward needed to wait more than a month to pop in that tape and has watched it maybe 20 times.
The San Francisco 49ers signed cornerback Jamar Taylor to a one-year contract.
The San Francisco 49ers have signed first-round draft picks Javon Kinlaw and Brandon Aiyuk to four-year deals, the team said Friday.
San Francisco 49ers fullback Kyle Juszczyk is encouraged by how productive the team's virtual offseason has been.
The defending NFC champion Niners are returning 18 of 22 starters from a team that fell one quarter short of winning it all, the type of continuity that could be especially crucial during this virtual offseason.
The defending NFC champion 49ers acquired seven-time Pro Bowl left tackle Trent Williams from the Washington Redskins on Saturday for a pair of draft picks and later announced that six-time Pro Bowler Joe Staley is retiring.
General manager John Lynch was busy Thursday night, making a pair of trades and nabbing the Arizona State product with the 25th overall pick.
The 49ers made the draft's first trade and then added to their already loaded defensive line selecting Javon Kinlaw.
Arik Armstead, who had a breakout year in 2019, will remain with the San Francisco 49ers for the foreseeable future.
President Donald Trump has pardoned Edward DeBartolo Jr., the former San Francisco 49ers owner convicted in a gambling fraud scandal.
The San Francisco 49ers' Katie Sowers made history Sunday night, becoming the first woman to coach in the Super Bowl.
Shutting down Patrick Mahomes and the Kansas City Chiefs' passing game in the Super Bowl will be a far tougher challenge than anything the Niners have faced this season.
What the San Francisco 49ers are doing this year harkens back to 1981 when Bill Walsh, Joe Montana and Ronnie Lott led the franchise to its first Super Bowl title.
The family of a fallen soldier from Sacramento is getting tickets to the Super Bowl thanks to 49ers star tight end George Kittle.
Garoppolo acknowledged he hears the criticism that he didn't do much to get San Francisco this far and uses it as motivation.
The Super Bowl matchup is set with the Kansas City Chiefs facing off against the San Francisco 49ers in Super Bowl LIV, and this highly anticipated game has sent ticket prices soaring.
Fresh of their victory in the NFC Championship, the San Francisco 49ers hope to come into Super Bowl LIV in style wearing their popular throwback uniforms, according to a published report.
Two police officers were injured and a suspect was killed in a shooting at a shopping center in Sparks, Nevada, on Thursday, officials said.
After winning two gold medals at the Winter Olympics, Alysa Liu received a hero's welcome at a hometown celebration in Oakland.
Sacramento police say they are trying to get a suspect in a shooting into custody in the Oak Park area.
An aerial refueling tanker crashed in Western Iraq, U.S. officials said.
Just months remain until the California gubernatorial election, and CBS California is teaming up with local organizations for a live debate with the race's top candidates.
Two deputies and a suspect were shot in El Dorado County Thursday morning, authorities said.
Two police officers were injured and a suspect was killed in a shooting at a shopping center in Sparks, Nevada, on Thursday, officials said.
FBI memo warning that Iran may try to launch drones at California in a seaborne "surprise attack" raised concern Wednesday — but officials tell CBS News there is no known, specific threat underpinning it.
Two new polls have conservative commentator Steve Hilton, billionaire Tom Steyer and Rep. Eric Swalwell as the front-runners for California governor.
After winning two gold medals at the Winter Olympics, Alysa Liu received a hero's welcome at a hometown celebration in Oakland.
The Sacramento Police Department said officers shot a suspect near an elementary school in the Northgate area on Tuesday evening after responding to reports of a person armed with a knife.
While the infant was being taken to an area hospital, officials said the child's pulse returned and they began breathing on their own.
It's a busy afternoon at the Taylor Morrison Willdhawk community worksite in Sacramento. Before the nail-guns and hammers go to work, Stephanie Martinez ensures safety comes first.
U.S. Army Reserve Chief Warrant Officer Robert Marzan's presumed death in Iran adds to the long list of California Gold Star Families who have lost a loved one in the line of duty.
A Sacramento County jury has convicted a man of first-degree murder in a deadly shooting that happened three and a half years ago in the city's Fab 40s neighborhood.
Getting a gallon of gas for under $3? In California, it's possible if you choose the right pump.
Drivers across California are feeling the impact of soaring gas prices in what feels like overnight.
An 8-year-old child was airlifted to a hospital after plunging 30 feet from a chair lift at the Sierra-at-Tahoe ski resort over the weekend, authorities said.
The California Department of Motor Vehicles said the federal government is requiring approximately 13,000 non-domiciled commercial truck drivers statewide to have their licenses revoked, effective immediately.
California Democrats are showing signs of division as the race to replace Gov. Gavin Newsom grows increasingly crowded ahead of the June primary.
After winning two gold medals at the Winter Olympics, Alysa Liu received a hero's welcome at a hometown celebration in Oakland.
The San Francisco 49ers made official on Thursday one of the top free-agent acquisitions in the NFL this offseason, announcing Mike Evans was signed to a three-year deal.
LaMelo Ball scored 20 of his 30 points in the first half and the Charlotte Hornets beat the Sacramento Kings 117-109 on Wednesday night.
Sacramento outscored the Bulls 68-36 in the paint.
Even after enduring a brutal skid last season, the confident Athletics are talking about contending for the 2026 playoffs.
An aerial refueling tanker crashed in Western Iraq, U.S. officials said.
The first week of the U.S.'s war with Iran cost around $11.3 billion, military officials told members of Congress in a briefing this week, according to sources familiar with the meeting.
President Trump ordered the release of 172 million barrels of oil from the U.S.'s Strategic Petroleum Reserve on Wednesday, after oil prices rocketed to their highest levels in years amid the U.S.'s war with Iran.
FBI memo warning that Iran may try to launch drones at California in a seaborne "surprise attack" raised concern Wednesday — but officials tell CBS News there is no known, specific threat underpinning it.
Officers normally assigned to process Global Entry travelers had been reassigned to process other arriving travelers during the pause.
Food containing norovirus may smell and taste normal but still cause serious illness if consumed, FDA warns.
HHS Secretary RFK Jr. wants the popular coffee chains to prove their surgery drinks are safe for teens and suggested the Trump administration could place limits on your cup of coffee.
Public health officials say they've confirmed two cases of measles in Sacramento County.
Multiple elephant seal pups along the Northern California coast have tested positive for the deadly avian influenza, or bird flu, according to new research from the University of California.
Here's what to know about TrumpRx, including how it works, who can use it, and how much money it can save.
Finding the perfect dress isn't easy, but now, selling them could become a lot more challenging.
This weekend, Placer County is hosting its annual Sip Into Spring event, offering free or discounted tastings at more than 20 wineries along what's known as the Placer Wine Trail.
From fruits and veggies to car parts, economists project that businesses will pass along the cost of the tariffs to customers.
An economic blackout was underway Friday as activists nationwide encouraged people not to spend their money at large corporations, retailers and fast-food chains for 24 hours.
San Joaquin County's retail theft reporting app has only been around for six months and is already bringing a sense of calmness to local business owners.
President Trump and Gov. Gavin Newsom have made several different claims about California gas prices. Here's what we found.
This year-long investigation provides an unprecedented look at California's one-party supermajority legislature through the eyes of grieving parents who discover how California lawmakers kill popular bills by not voting.
This year-long investigation by CBS News California investigative correspondent Julie Watts examines the many components of California's new tougher-on-crime law.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
The California Highway Patrol captain accused of workers' compensation fraud was the commander in charge of the fatal Mahaney Park shootout in Roseville, three officers who worked under him at the time of the shootout said.
CBS13 and the Call Kurtis consumer investigative team devised an idea on how to lower what consumers owe on their credit cards -- and it begins with a simple phone call.
No one wants to think about death. However, it's important to plan on what happens to your digital assets after you die.
After spending $18,000 on waterproof laminate floors, a Natomas couple spotted damage after the first cleaning.
More than a year after Hai Pham canceled the trial membership, he kept getting charged every month for it.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
Six months after a California wildfire destroyed dozens of homes in the Tuolumne County community of Chinese Camp, officials say debris removal is now complete and properties are being returned to their owners.
A man has been arrested and charged in connection with the Tiger Fire that burned 118 acres in California's Amador County last summer and forced evacuations near Pioneer.
A major home developer is rethinking how communities are built in wildfire-prone areas and the future is taking shape in El Dorado County.
San Joaquin County secured a grant aimed at helping to build a wildfire protection plan for the entire county.
More than two dozen structures were destroyed in a wildfire in the eastern Sierra Nevada mountains on Wednesday afternoon, officials said.
A Sacramento County dog picked up thousands of miles from home after he went missing five years ago was reunited with his family on Wednesday.
What started as a suspicious circumstances call for Rancho Cordova police ended with a newborn surprise.
A once-empty lot behind Church of the Cross in north Modesto now hosts a thriving community garden with more than 140 plots and growers from across the globe.
A Sacramento-area middle school history and English teacher is in the running to win big as America's Favorite Teacher, a title her students think she is more than worthy of being awarded.
Junior Romello Bruhn of Woodland Christian High School is closer than ever to scoring 3,000 career points, something only 13 high school athletes have accomplished in California state history.
Carmela Karcher reports.
Sacramento police say they are trying to get a suspect in a shooting into custody in the Oak Park area.
Two El Dorado County deputies and a suspect were shot in Camino Thursday morning, authorities said.
Two deputies were shot in Camino, the El Dorado County sheriff’s office says. A suspect was also shot.
Here's a look at the weather forecast Thursday afternoon.