Watch CBS News
Family pride, bragging rights, even control of the dinner-table conversation. It's all part of a high-stakes poker game in the first-ever head-to-head matchup between 49ers tight end Vernon Davis and Colts cornerback Vontae Davis.
The scoreboard is not the only place where the 49ers were beat up this past weekend. After a relatively injury free start to the season, there are several players who now fill up the injury report, but the news is not all bad. Their opponent has two very significant injuries, and this game will not be nearly as physical as the war that was the game against Seattle.
Coming off an embarrassing loss to the Seattle Seahawks Sunday night, the San Francisco 49ers face the Indianapolis Colts at Candlestick Sunday afternoon. "You don't have a lot of time to pout," John Madden told the KCBS Radio morning crew.
The San Francisco 49ers play the Indianapolis Colts at Candlestick Sunday in a game featuring a former Stanford coach, Jim Harbaugh, and his star college quarterback, Andrew Luck. "Andrew Luck and that Colt offense, they can play," John Madden told the KCBS Radio morning crew.
Trent Richardson will now get a crash course on the Colts' offense and is likely to play this weekend at San Francisco.
No matter that opponents are stacking extra defenders next to the line of scrimmage. The San Francisco 49ers are determined to run the football successfully, a key element of their offense that has been missing through the first two weeks of the season.
In two games, the Seahawks' swarming defense has surrendered only 10 points, shutting down Carolina and San Francisco. They've made Cam Newton and Colin Kaepernick look confused, created game-changing turnovers and shown just how much fun it is making the game miserable for others.
Attorneys for San Francisco 49ers linebacker Aldon Smith and former Niners tight end Delanie Walker have filed a response to a civil lawsuit filed by a Northern California man who says he was shot during a party at Smith's house.
They will be reunited as opponents Sunday, finding themselves in the strange position of game-planning against each other in Week 3 while trying to bounce back from tough losses.
When Vernon Davis and Jim Harbaugh eye the Colts sideline this Sunday, they will each look a little differently at a player looking back at them. There are two members of the opposition that have close ties to the two, and should make for some interesting football come Sunday.
San Francisco 49ers nosetackle Ian Williams was officially placed on injured reserve Tuesday with a broken left ankle. The 49ers also signed fullback Owen Marecic to a one-year contact on Tuesday.
"If you do a helmet-to-helmet, you probably aren't going to get suspended," John Madden told the KCBS Radio morning crew.
The San Francisco 49ers have committed 23 penalties in their first two games for 206 yards, 12 of those for 121 yards against the Seattle Seahawks this past Sunday. They were flagged for two personal fouls and an unsportsmanlike conduct penalty in the fourth quarter.
It looks as though EA Sports manufactured the "eyebrow-shaving" bet that was supposedly setup between quarterbacks Russell Wilson and Colin Kaepernick.
San Francisco welcomes second year sensation Andrew Luck to Candlestick in this Week 3 match up. After leading the Colts to the playoffs as a rookie, Luck is back in his second year to show that he is the real deal. He has weapons around him on offense and a respectable defense, but there is no secret that he is the heart and soul of this team, and they key to their success week in and week out.
The NFC West champions sustained several injuries during Sunday night's 29-3 road defeat at the hands of division rival Seattle, including the expected season-ending ankle injury for nose tackle Ian Williams.
The Seattle Seahawks humbled the San Francisco 49ers in Seattle Sunday night, winning 29-3. "(Seattle is) a legitimate tough team, with a legitimate defense," John Madden told the KCBS Radio morning crew.
The Seahawks were left celebrating after another convincing victory over the 49ers, this time a 29-3 rout on Sunday night. It was an addendum to the 42-13 blowout the Seahawks served on San Francisco last December, but this victory means more.
The 49ers and Seahawks met Sunday night, and for the second straight meeting, the Seattle defense was the difference. This game featured the two top dogs of the NFC West, and the Seahawks sent a message not only to the defending division winner, but one to the entire NFL.
Seattle flustered Colin Kaepernick into his worst passing game as a starter and the Seahawks dominated the San Francisco 49ers in a 29-3 win Sunday night.
Colin Kaepernick and Russell Wilson are both looking to build on the best statistical performances of their respective careers Sunday night, when the 49ers visit the Seahawks in a meeting of bitter NFC West rivals.
Week 2 may seem too early for this much hype and anticipation, but the Seahawks and 49ers understand the importance of Sunday evening's NFC West showdown.
Surprises were the order of the NFL's opening weekend, and they present some intriguing possibilities for Week 2.
Former NFL great Steve Young will be one of the keynote speakers at a three-day conference in Salt Lake City exploring how the Mormon faith is dealing with gays and lesbians.
Tackling is one area where the 49ers' defense will look to get better entering Sunday evening's showdown against a top NFC opponent that ran over and through the San Francisco defense the last time the divisional rivals met.
One person died and three others, including a child, were injured in a shooting Wednesday night at a high school graduation in Northern California, officials said.
The Howard Jarvis Taxpayers Association has qualified a proposition that would end the citizens' initiative loophole, requiring that all tax measures get 2/3 for passage. It would also retroactively invalidate any new parcel tax that passed with less than 2/3.
The fire is near Deer Valley and Balfour roads. Cal Fire said Contra Costa Fire Protection District crews are also at the scene.
Just before 6:30 a.m., police were called to the 900 block of Geneva Avenue, near Paris Street, for a report of a deceased person on the street.
Police said the investigation began May 30 when a property manager of a California Street apartment building called them, and said a deceased person was found inside one of the homes.
One person died and three others, including a child, were injured in a shooting Wednesday night at a high school graduation in Northern California, officials said.
The Howard Jarvis Taxpayers Association has qualified a proposition that would end the citizens' initiative loophole, requiring that all tax measures get 2/3 for passage. It would also retroactively invalidate any new parcel tax that passed with less than 2/3.
The fire is near Deer Valley and Balfour roads. Cal Fire said Contra Costa Fire Protection District crews are also at the scene.
Just before 6:30 a.m., police were called to the 900 block of Geneva Avenue, near Paris Street, for a report of a deceased person on the street.
Police said the investigation began May 30 when a property manager of a California Street apartment building called them, and said a deceased person was found inside one of the homes.
Just before 6:30 a.m., police were called to the 900 block of Geneva Avenue, near Paris Street, for a report of a deceased person on the street.
As the nation celebrates 250 years, a Bay Area city has updated a monument to the region's industrial history with a fresh coat of paint.
Authorities in Central California said a married couple from the San Francisco Bay Area drowned during a visit to Kings Canyon National Park over the Memorial Day holiday.
Voters in San Francisco on Tuesday advanced San Francisco Supervisor Connie Chan and state Sen. Scott Wiener in the race to succeed former House Speaker Nancy Pelosi in California's 11th Congressional District, CBS News projects.
A man arrested following a shootout that critically injured a San Francisco police officer late Sunday night is facing multiple felony charges, including attempted murder, prosecutors said.
The fire is near Deer Valley and Balfour roads. Cal Fire said Contra Costa Fire Protection District crews are also at the scene.
Police said the investigation began May 30 when a property manager of a California Street apartment building called them, and said a deceased person was found inside one of the homes.
In the race for Alameda County District Attorney, incumbent Ursula Jones Dickson held the lead over her predecessor and a political newcomer in early returns.
Voters in California's 14th Congressional District on Tuesday advanced state Sen. Aisha Wahab in the race to succeed former Rep. Eric Swalwell, CBS News projects.
A steady stream of people showed up at the Elections Office drop box just to feel the sense of security of depositing their ballot right outside of where it's going to be counted.
A San Jose man was sentenced to over 10 years in federal prison on Tuesday after he pleaded guilty to a 2024 attack of a postal worker, prosecutors said.
Authorities in Monterey County announced an arrest Tuesday in connection with a fire that burned the nation's oldest Buddhist monastery in late March.
Authorities on California's Central Coast arrested two people Sunday suspected of vandalizing robots performing assessments on sidewalks last week.
Only two gubernatorial candidates will advance to the general election in November.
One man has died after a shooting in downtown San Jose that left three men injured early Sunday, police said.
More than four decades after a Sonoma County man was sexually assaulted and murdered, deputies said they have solved the case.
A small plane crashed at an airport in Sonoma County on Wednesday, injuring three people, authorities said.
Authorities in Napa County arrested a domestic violence suspect following a pursuit that ended with a crash into a power pole Wednesday morning.
A vigil was held on Monday by friends and family of Pearl Pinson, 10 years after the Vallejo teen disappeared on her way to school.
A man who called 911 repeatedly asking for help in Santa Rosa and who had climbed atop of a bus in Santa Rosa spent the next 10 hours perched atop the bus before officers were able to safely bring him down, police said.
Santa Clara County authorities confirmed Wednesday that an arrest warrant has been issued for 49ers receiver Brandon Aiyuk.
Kayla Thornton made five 3-pointers and had 19 points and eight rebounds, Janelle Salaun came off the bench to contribute 18 points and the Golden State Valkyries jumped out to a big lead before holding off a late rally by the Portland Fire for a 95-77 win Tuesday night in a Commissioner's Cup game.
Kyle Harrison matched his season high with 12 strikeouts, Jake Bauers hit a three-run homer and the Milwaukee Brewers beat the San Francisco Giants 8-3.
San Francisco Giants reliever Joel Peguero has gone on the 60-day injured list with a left hamstring strain.
Rick Adelman, the Hall of Fame coach who led the Sacramento Kings through the most successful era in franchise history, has died, the National Basketball Coaches Association said on Monday. He was 79.
One person died and three others, including a child, were injured in a shooting Wednesday night at a high school graduation in Northern California, officials said.
Police said the investigation began May 30 when a property manager of a California Street apartment building called them, and said a deceased person was found inside one of the homes.
A man arrested following a shootout that critically injured a San Francisco police officer late Sunday night is facing multiple felony charges, including attempted murder, prosecutors said.
A San Jose man was sentenced to over 10 years in federal prison on Tuesday after he pleaded guilty to a 2024 attack of a postal worker, prosecutors said.
A man has been charged with bringing an explosive device into Sacramento International Airport, federal prosecutors announced.
Authorities on California's Central Coast arrested two people Sunday suspected of vandalizing robots performing assessments on sidewalks last week.
A Virginia man is suing Amazon over Ring's "Familiar Faces" feature, alleging the technology violates people's privacy.
Florida has become the first state to sue OpenAI and its CEO, Sam Altman.
California is suing the company formerly known as 23andMe over its 2023 breach of ancestry and genetic data, one of the most consequentilal data breaches ever.
AI-fueled delusions can happen when chatbots respond to grandiose, paranoid or imaginary ideas with affirmation or encouragement.
Grocery sales at two Target stores in San Jose were halted over the past week, after health inspectors found evidence of rodent infestations.
WHO chief Tedros Adhanom Ghebreyesus says risks from the Ebola outbreak in Congo and Uganda are "high at the national and regional levels, and low at the global level."
The cruise ship hit by a deadly hantavirus outbreak has docked at the Dutch port of Rotterdam for disinfection, wrapping up a troubled journey that put world health authorities on alert.
At least 80 deaths have been reported in a new Ebola disease outbreak in Congo and Uganda, authorities said.
California public health officials said on Wednesday that they have identified a fifth resident who may have been exposed to the Andes hantavirus due to the outbreak on the MV Hondius cruise ship.
The Howard Jarvis Taxpayers Association has qualified a proposition that would end the citizens' initiative loophole, requiring that all tax measures get 2/3 for passage. It would also retroactively invalidate any new parcel tax that passed with less than 2/3.
In the race for Alameda County District Attorney, incumbent Ursula Jones Dickson held the lead over her predecessor and a political newcomer in early returns.
Voters in San Francisco on Tuesday advanced San Francisco Supervisor Connie Chan and state Sen. Scott Wiener in the race to succeed former House Speaker Nancy Pelosi in California's 11th Congressional District, CBS News projects.
In San Francisco, two competing measures that seek to change the Top Executive Pay Tax are trailing in early returns.
Voters in California's 14th Congressional District on Tuesday advanced state Sen. Aisha Wahab in the race to succeed former Rep. Eric Swalwell, CBS News projects.
Jason Collins, the NBA's first openly gay player, who went on to become a pioneer for inclusion and an ambassador for the league, has died, his family announced Tuesday.
Philz Coffee will once again sport the Pride flag at its cafés after a directive to have them and other flags removed created a backlash.
The Trump administration agreed to restore the Stonewall National Monument's Pride flag in Greenwich Village after it was removed.
Philz Coffee's move to remove the Pride flag and all other flags from their stores is brewing up some strong reaction.
Transgender women athletes are now excluded from women's events at the Olympics after the IOC agreed to a new eligibility policy on Thursday.
Peabo Bryson, a two-time Grammy-winning singer and songwriter known for Disney movie hits "Beauty and the Beast" and "A Whole New World," has died at age 75.
What began as a Bay Area gathering centered on music, food and community has grown into a global movement.
No one knew it at the time, but at the end of their 1966 North American Tour, the "Fab Four" would never again play a paid, public ticketed concert.
President Trump said he is considering replacing the Freedom 250 concert series with a rally after many artists dropped out.
San Francisco rapper Frak, who first gained recognition in the battle rap scene before appearing on MTV, BET, and VH1's Wild 'N Out, says his work is also deeply connected to Jewish identity and culture.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Loureen Ayyoub reports on the Presidio Performing Arts Foundation.
Andrea Nakano reports on a shooting at a graduation ceremony.
Len Ramirez reports on the California Room in San Jose.
John Ramos reports on how citizens initiatives are helping bypass Prop 13.
Katie Nielsen reports on the Irvington High School football program.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.