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The NFC West champions sustained several injuries during Sunday night's 29-3 road defeat at the hands of division rival Seattle, including the expected season-ending ankle injury for nose tackle Ian Williams.
Starting strong safety Tyvon Branch will likely miss significant time with a right ankle injury starting with next Monday night's game against Peyton Manning and the high-powered Denver Broncos.
The Seattle Seahawks humbled the San Francisco 49ers in Seattle Sunday night, winning 29-3. "(Seattle is) a legitimate tough team, with a legitimate defense," John Madden told the KCBS Radio morning crew.
Green Bay's Aaron Rodgers was one of three NFL quarterbacks who threw for more than 400 yards without an interception Sunday. "They're saying now that Aaron Rodgers is the best quarterback in the NFL, and I'm starting to lean that way myself," John Madden told the KCBS Radio morning crew.
The Seahawks were left celebrating after another convincing victory over the 49ers, this time a 29-3 rout on Sunday night. It was an addendum to the 42-13 blowout the Seahawks served on San Francisco last December, but this victory means more.
A week after Terrelle Pryor set a franchise record for quarterbacks with 112 yards rushing, Darren McFadden capitalized on the increased focus on the quarterback in nearly two years.
The 49ers and Seahawks met Sunday night, and for the second straight meeting, the Seattle defense was the difference. This game featured the two top dogs of the NFC West, and the Seahawks sent a message not only to the defending division winner, but one to the entire NFL.
The Oakland Raiders accomplished their first victory of the season against a struggling Jacksonville Jaguars with a performance that should have been better.
Seattle flustered Colin Kaepernick into his worst passing game as a starter and the Seahawks dominated the San Francisco 49ers in a 29-3 win Sunday night.
Darren McFadden ran for 129 yards and Oakland's defense held the Jaguars out of the end zone until the closing minutes, as the Raiders won their home opener 19-9 on Sunday.
Colin Kaepernick and Russell Wilson are both looking to build on the best statistical performances of their respective careers Sunday night, when the 49ers visit the Seahawks in a meeting of bitter NFC West rivals.
Week 2 may seem too early for this much hype and anticipation, but the Seahawks and 49ers understand the importance of Sunday evening's NFC West showdown.
While the Oakland Raiders hope they have found their quarterback of the future in Terrelle Pryor, the jury is still out on whether oft-injured Blaine Gabbert will be running the Jacksonville Jaguars' offense for years to come.
Here are five other things to look for when the Jaguars and Raiders play Sunday...
Surprises were the order of the NFL's opening weekend, and they present some intriguing possibilities for Week 2.
A slow start is nothing new for Oakland Raiders running back Darren McFadden. Neither is the criticism he's endured for the past several seasons.
Former NFL great Steve Young will be one of the keynote speakers at a three-day conference in Salt Lake City exploring how the Mormon faith is dealing with gays and lesbians.
Tackling is one area where the 49ers' defense will look to get better entering Sunday evening's showdown against a top NFC opponent that ran over and through the San Francisco defense the last time the divisional rivals met.
It's only Week 2, and as to be expected injuries are not going to determine the outcome of the game between the 49ers and Seahawks. While Seattle might be shorthanded in the secondary they still have plenty of bodies ready to go, and the winner of this game will be the team that plays better, not the one that is healthier going into the game.
The left tackle issue for the Oakland Raiders is still at large. However, the issue will not or should not be a problem against the Jacksonville Jaguars for week 2.
The Oakland Raiders are favored to beat the Jacksonville Jaguars in Oakland Sunday. "The one thing they can't be is overconfident," John Madden told the KCBS Radio morning crew. "You can't have a good loss on the road and get overconfident by it.
In the latest match-up in what is becoming one of the NFL's best rivalries, the San Francisco 49ers face the Seattle Seahawks at CenturyLink Field Sunday.
Eric Reid's first game as a rookie for San Francisco came against one of the league's best quarterbacks in Aaron Rodgers. Reid shined, making an interception and six tackles. The next task is equally tough for the first-rounder.
Sebastian Janikowski was surprised - and a bit angry - to read a published report quoting Jacksonville kicker Josh Scobee, claiming Janikowski annually roots for the Oakland Athletics to miss the playoffs so the Coliseum dirt can be replaced with sod.
Bay Area Rapid Transit has started offering free Wi-Fi connectivity at some of its busiest train stations ahead of Super Bowl LX-related events, the agency announced.
A year after CBS News California Investigates exposed secrecy inside the California FAIR Plan, the insurance commissioner is backing a bill that would open meetings and financial records and require public reporting for the state's insurer of last resort.
A speech therapist providing in-home care to a toddler in San Jose was arrested after allegedly sexually assaulting the child, police said on Tuesday.
An elderly pedestrian died of her injuries after she was hit by a vehicle in Millbrae on Monday, authorities said.
Starting March 1, the SBA will no longer guarantee loans for small businesses owned by foreign nationals, including green card holders.
Bay Area Rapid Transit has started offering free Wi-Fi connectivity at some of its busiest train stations ahead of Super Bowl LX-related events, the agency announced.
A speech therapist providing in-home care to a toddler in San Jose was arrested after allegedly sexually assaulting the child, police said on Tuesday.
An elderly pedestrian died of her injuries after she was hit by a vehicle in Millbrae on Monday, authorities said.
Starting March 1, the SBA will no longer guarantee loans for small businesses owned by foreign nationals, including green card holders.
Two teenagers were arrested as suspects in a triple shooting last week in San Francisco that killed a 15-year-old girl, authorities said Tuesday.
Bay Area Rapid Transit has started offering free Wi-Fi connectivity at some of its busiest train stations ahead of Super Bowl LX-related events, the agency announced.
An elderly pedestrian died of her injuries after she was hit by a vehicle in Millbrae on Monday, authorities said.
Two teenagers were arrested as suspects in a triple shooting last week in San Francisco that killed a 15-year-old girl, authorities said Tuesday.
An iconic Mel's Drive-In location in San Francisco was damaged in a fire early Tuesday morning.
NPU Live, the company behind The Midway and Portola Festival, is hosting several concerts and parties in one of the city's unique spaces, Pier 80.
A dismembered body was discovered in an industrial area of Oakland over the weekend, authorities said on Monday.
Another swarm of earthquakes centered in San Ramon shook the East Bay on Monday morning, including a 4.2 magnitude quake felt across a wide swath of the Bay Area, authorities said.
One person died and two others were injured after a driver took off from a police sergeant and crashed into a parked vehicle in San Leandro late Saturday night, police said.
The planned shutdown of the Valero refinery in Benicia is expected to have a major economic impact on the city, even as environmental advocates welcome the closure.
The West Oakland BART station is closed and major delays are being reported on the transit system Friday due to a fatality at the station, officials said.
A speech therapist providing in-home care to a toddler in San Jose was arrested after allegedly sexually assaulting the child, police said on Tuesday.
The low-altitude flights are happening through Wednesday, and they are being done to measure expected background radiation ahead of the Super Bowl, the National Nuclear Security Administration said.
The Mountain View Police Department is suspending the use of ALPR cameras after the discovery of unauthorized access to data by federal and state agencies, the police chief said on Monday.
The shooting happened around 4:48 p.m. Sunday in the 1500 block of Winchester Boulevard. When police arrived at the scene, they found a 17-year-old boy who had been shot at least once.
A man suspected of setting multiple vehicles on fire in San Jose last month was arrested, police said on Monday.
Four suspects remain at large and two were arrested after an armed robbery at a Petaluma jewelry store on Saturday, police said.
A Bay Area environmental group is pushing for more restrictions and protection at one of the largest shale reefs in North America. As part of its proposal to the state, all fishing would be banned.
Yountville Commons will be located adjacent to City Hall at the site of the old Yountville Elementary School, which closed in 2000 because there weren't enough children in the town to keep it open. It will include about 120 affordable homes inside a large new public park.
The federal government said that unless homeowners downstream consent to it, the removal of the bridge cannot go forward. Meanwhile, residents opposed to the demolition say it's time to stop trying to fight Mother Nature.
Hundreds of demonstrators gathered in Marin County to protest against ICE and Border Patrol agents following the killing of Alex Pretti on Saturday.
Tom Brady is not taking sides in Super Bowl LX between his former team, the Patriots, and the Seahawks.
Maybe the game itself will live up to the hype, because Super Bowl Opening Night was calmer than usual.
The San Francisco 49ers are hiring former Atlanta Falcons head coach Raheem Morris as their new defensive coordinator in hopes of finding a long-term solution to a revolving door at the spot.
Free agent infielder Luis Arraez and the San Francisco Giants have agreed to a $12 million, one-year contract, according to a person with knowledge of the negotiations.
Joel Farabee's short-handed goal at 6:53 of the third period broke a tie and sent the Calgary Flames to a 3-2 victory over the San Jose Sharks.
A speech therapist providing in-home care to a toddler in San Jose was arrested after allegedly sexually assaulting the child, police said on Tuesday.
Two teenagers were arrested as suspects in a triple shooting last week in San Francisco that killed a 15-year-old girl, authorities said Tuesday.
The Democratic members of a U.S. House committee have released the findings of a report examining last month's fatal shootings in Minneapolis by federal immigration officers.
The victim killed in a triple shooting at a San Francisco park on Friday was identified as a 15-year-old girl, her school confirmed on Monday.
The shooting happened around 4:48 p.m. Sunday in the 1500 block of Winchester Boulevard. When police arrived at the scene, they found a 17-year-old boy who had been shot at least once.
A former Google engineer has been convicted on multiple federal charges for stealing the tech giant's trade secrets on artificial intelligence to benefit Chinese companies he secretly worked for, federal prosecutors said.
The rideshare company is getting into the business of providing real-world driving data to autonomous vehicle developers. Here's why.
Waymo announced Thursday that its robotaxi service is now available to and from San Francisco International Airport, ahead of upcoming major events in the Bay Area including the Super Bowl and World Cup.
The Fremont factory will still manufacture Model 3 and Y, but the space where Model S and X are made will instead focus on mass production of Tesla's Gen 3 Optimus robots.
Some TikTok users are raising questions about the app's new terms and conditions after the social media platform's split from its China-based parent.
Health officials in the East Bay said a man has died from consuming toxic wild mushrooms, amid an ongoing spike in mushroom-related poisonings throughout California.
Health officials in Napa County confirmed Wednesday that a child has been diagnosed with measles in the county's first case in nearly 15 years.
Over the years, Dr. Rachel Forer has found plenty of ways to take the sting out of going to the dentist. But no matter how hard she tried, fear had a way of creeping in.
Officials in San Mateo County are the latest in the Bay Area to warn residents to not forage for wild mushrooms, amid a rise in mushroom poisonings that have led to illnesses and even deaths.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
Starting March 1, the SBA will no longer guarantee loans for small businesses owned by foreign nationals, including green card holders.
Hillary Clinton will appear for a deposition on Feb. 26, while former President Bill Clinton will appear on Feb. 27, according to the House Oversight Committee.
The Democratic members of a U.S. House committee have released the findings of a report examining last month's fatal shootings in Minneapolis by federal immigration officers.
The Clintons made a last-ditch effort to avoid a contempt vote.
A slew of notable individuals appear in the latest Justice Department release of Jeffrey Epstein files.
The billionaire and philanthropist MacKenzie Scott donated $45 million to The Trevor Project, a nonprofit focused on suicide prevention and advocacy for LGBTQ young people.
Oasis nightclub announced plans to close six months ago. New Year's Eve was slated for the final performance. A last-minute, multi-million dollar donation turned the final curtain call into an encore performance.
A 16-year FBI employee has filed a lawsuit alleging he was fired last month because he had a Pride flag displayed near his desk.
A group of transgender members of the U.S. Air Force and Space Force forced to leave active duty under the Trump administration's policies say their benefits were revoked in a rare move.
California state Sen. Scott Wiener of San Francisco announced Wednesday that he is running for Nancy Pelosi's congressional seat next year.
NPU Live, the company behind The Midway and Portola Festival, is hosting several concerts and parties in one of the city's unique spaces, Pier 80.
The 2026 Grammy Awards recognized the best of the best in music from last year, with big wins for Kendrick Lamar and Bad Bunny. Here's the full list of winners and nominees.
Complete closure of the performing arts center in Washington, D.C., will start on July 4, Mr. Trump said. It's not yet clear how extensive the changes to the building might be.
Music's biggest night returned Sunday with the 68th annual Grammy Awards. Here is how to watch and stream and what to know.
In 1971, Demond Wilson appeared on an episode of "All in the Family," a role that led him to land a lead part in "Sanford and Son."
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
The NFL's chief security officer said Tuesday that the U.S. Immigration and Customs Enforcement has no planned operations at Super Bowl LX at Levi’s Stadium on Sunday.
Meteorologist Zoe Mintz zooms in on the Central Valley to explain why the central part of the state gets socked in with fog while the Bay Area's air quality suffers.
Meteorologist Zoe Mintz says after mostly clear weather there is a chance of rain by the end of the week, possibly on Super Bowl Sunday.
Amanda Hari reports on Mountain View's discovery of unauthorized access to data by federal and state agencies. Website: http://kpix.com/ YouTube: http://www.youtube.com/CBSSanFrancisco Facebook: https://www.facebook.com/CBSSanFrancisco Instagram: https://www.instagram.com/kpixtv/ Twitter: https://twitter.com/KPIXtv
Sara Donchey reports on Super Bowl festivities in San Francisco ahead of game day. Website: http://kpix.com/ YouTube: http://www.youtube.com/CBSSanFrancisco Facebook: https://www.facebook.com/CBSSanFrancisco Instagram: https://www.instagram.com/kpixtv/ Twitter: https://twitter.com/KPIXtv
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.