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This time it was the passing game that set up the run and led to a 45-3 win over the visiting Buffalo Bills. Alex Smith finished with over 300 yards passing while the defense played another impressive game. With momentum on their side, the 49ers will take on the New York Giants next week in the biggest game of the year for San Francisco.
Colin Keapernick made his presence felt in last week's win over the New York Jets. He size and speed put him in the same conversation with Cam Newton and Tim Tebow, but he is still far from earning a starting role in this league. He is on the right team with the right coach and will have a chance to show what he is made of eventually.
San Francisco responded after last weeks last with a 34-0 win over the New York Jets. The team did not play great, but dominated the Jets the whole day and showed that they are the team with a back up quarterback who can make a difference.
After failing to do anything offensively last week, there will be pressure on the offense to put some points on the board, and that will have to come by air. Smith and his receivers will need to get up to speed if they want to avoid another loss by only scoring 13 points like last week.
The San Francisco 49ers are playing the Minnesota Vikings this week and if they stay focused they should cruise to the win. They will have to contain Minnesota running back Adrian Peterson, but for a team has such a strong defense this should not be a problem. The offense will stick to the same game plan it has used all season.
ESPN's NFL Power Rankings have the 49ers looking down at the rest of the league. The team was a unanimous pick as they are miles in front of their competition in the early season. With a young team they are only poised to get better moving forward.
The San Francisco 49ers took the lead early and never looked back in their 27-19 win over the Lions. Led by Alex Smith, they scored just enough to keep the game out of reach and recovered an onside kick late to seal the win.
The San Francisco Defense was the story on Sunday keeping the Green Bay Packers off the scoreboard for most of the game and stepped up late to hold off the Packers rally. Alex Smith was almost as impressive committing zero turnovers and answering each time the Packers threatened to come back and steal the game. The entire team earned a grade of an A and are perhaps the most complete team in the league.
Alex Smith is key to San Francisco 49ers' success in 2012. With everything set up for him to succeed, everyone will be watching to see if he fails.
Quarterback Alex Smith has signed a three-year deal with the San Francisco 49ers that will pay him $8 million per season with $16.5 million guaranteed.
A person with knowledge of the negotiations says Alex Smith and the San Francisco 49ers are working to finalize a three-year contract.
San Francisco 49ers free agent quarterback Alex Smith has left the Miami Dolphins' complex after a 5½-hour meeting with the team.
Could this be a dream come true for 49er fans or a crafty power play by Harbaugh and company to keep four-time MVP Payton Manning away from the NFC West?
Drew Brees piled up points, yards and accolades in a record-setting season for the New Orleans Saints.
t the end of last season, Doug Smith never imagined his son would play for the San Francisco 49ers again, not after hearing the quarterback get booed out of Candlestick Park and yet another coaching change on the way.
The Saint John's Program for Real Change has been helping women and children in Sacramento for the last four decades with housing and education.
A slow start to Sierra snowfall is putting early-season pressure on Truckee businesses that rely on winter tourism, even as ski resorts race to open using man-made snow.
As the holiday season shifts into high gear, struggles are mounting for the Sunrise Mall in Citrus Heights, with more stores shutting their doors.
Deputies said they believe the total street value of the seized items is more than $2.5 million.
The Trump administration will start sending more water to California farmers in the state's crop-rich Central Valley.
As the holiday season shifts into high gear, struggles are mounting for the Sunrise Mall in Citrus Heights, with more stores shutting their doors.
The Saint John's Program for Real Change has been helping women and children in Sacramento for the last four decades with housing and education.
A slow start to Sierra snowfall is putting early-season pressure on Truckee businesses that rely on winter tourism, even as ski resorts race to open using man-made snow.
Deputies said they believe the total street value of the seized items is more than $2.5 million.
Private First-Class Tanner F. Rubio was inside a tactical vehicle when a mishap occurred during routine training.
Sacramento State Hornets head football coach Brennan Marion is leaving the program after just one season to become the offensive coordinator for Deion Sanders's Colorado Buffaloes.
A domestic violence suspect who fled from and fired at Sacramento County Sheriff's deputies early Monday morning before engaging in a hours-long standoff died from a self-inflicted gunshot wound, the Sheriff's Office said.
Last week, the California DMV approved a major expansion for Waymo, allowing the company to bring its robotaxis to more regions across the state, including in parts of Solano, Yolo and Sacramento counties.
The Sacramento County Sheriff's Office said a suspect was arrested in connection with the deadly shooting that happened in the Del Paso Heights area of Sacramento.
A birthday surprise brought a retired racehorse to an East Sacramento neighborhood, all because of a "longshot" call put out on social media and a pair of willing volunteers.
The Trump administration will start sending more water to California farmers in the state's crop-rich Central Valley.
A California animal rights activist who took four chickens from a Perdue Farms poultry plant in Sonoma County was sentenced on Wednesday to 90 days in jail following her conviction in October.
California's essential health care facilities are wasting money on expensive contract labor amid chronic staffing shortages, even as agencies involved report hundreds of millions of dollars in savings from unfilled positions, a new report shows.
California unveiled a new online portal on Wednesday for residents to report alleged misconduct by federal agents during operations to enforce immigration laws.
The family of a teenage boy identified him as one of the four people killed at a Stockton birthday party over the weekend, while the city's school district offered support resources for students and staff affected.
The 2026 Men's World Cup will be held across the United States, Canada and Mexico next summer.
The Athletics are on track to open their new Las Vegas stadium on time, officials said Thursday.
Sacramento State Hornets head football coach Brennan Marion is leaving the program after just one season to become the offensive coordinator for Deion Sanders's Colorado Buffaloes.
Former Angels and Rangers manager Ron Washington is returning to the Bay Area to become infield coach for the San Francisco Giants on new manager Tony Vitello's staff.
Alperen Sengun had 28 points and 10 rebounds, Kevin Durant scored 24 points and the Houston Rockets beat the Sacramento Kings 121-95 on Wednesday night.
The Supreme Court said Friday it will decide the legality of President Trump's executive order that seeks to end birthright citizenship.
California lobbyist Greg Campbell pleaded guilty Thursday to charges in connection with stealing funds from Xavier Becerra's dormant campaign account.
Texas approved a new congressional map this summer after Trump urged state GOP lawmakers to craft new House district lines to help Republicans hold onto their majority in the 2026 midterms.
Authorities say the FBI has arrested a man suspected of placing pipe bombs outside RNC and DNC headquarters on the eve of the Jan. 6, 2021, Capitol riot.
In the aftermath of the Stockton mass shooting, there are new calls to restore funding to a gun violence prevention program forced to close in March due to federal Department of Government Efficiency cuts.
The plan is to embed street medicine training directly into residency programs across multiple hospitals.
Consumers with the imported pans should throw them away due to the severe health risks posed by lead, the agency warns.
Ray Cathey is on a journey from silence to new sounds. Cathey's hearing took a pounding when he was an air rescue paramedic during the Vietnam War.
ByHeart said it can't rule out that all of its baby formula across all product lots could be contaminated, citing recent test results.
In the last decade, more than 50 maternity wards have closed in California hospitals. Now, state lawmakers are delivering new rules to make it easier for moms to use a midwife.
Finding the perfect dress isn't easy, but now, selling them could become a lot more challenging.
This weekend, Placer County is hosting its annual Sip Into Spring event, offering free or discounted tastings at more than 20 wineries along what's known as the Placer Wine Trail.
From fruits and veggies to car parts, economists project that businesses will pass along the cost of the tariffs to customers.
An economic blackout was underway Friday as activists nationwide encouraged people not to spend their money at large corporations, retailers and fast-food chains for 24 hours.
San Joaquin County's retail theft reporting app has only been around for six months and is already bringing a sense of calmness to local business owners.
President Trump and Gov. Gavin Newsom have made several different claims about California gas prices. Here's what we found.
This year-long investigation provides an unprecedented look at California's one-party supermajority legislature through the eyes of grieving parents who discover how California lawmakers kill popular bills by not voting.
This year-long investigation by CBS News California investigative correspondent Julie Watts examines the many components of California's new tougher-on-crime law.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
The California Highway Patrol captain accused of workers' compensation fraud was the commander in charge of the fatal Mahaney Park shootout in Roseville, three officers who worked under him at the time of the shootout said.
CBS13 and the Call Kurtis consumer investigative team devised an idea on how to lower what consumers owe on their credit cards -- and it begins with a simple phone call.
No one wants to think about death. However, it's important to plan on what happens to your digital assets after you die.
After spending $18,000 on waterproof laminate floors, a Natomas couple spotted damage after the first cleaning.
More than a year after Hai Pham canceled the trial membership, he kept getting charged every month for it.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
More than two dozen structures were destroyed in a wildfire in the eastern Sierra Nevada mountains on Wednesday afternoon, officials said.
Clean-up has started in Chinese Camp after the TCU September Lightning Complex Fire ripped through the Gold Rush town earlier this month.
The fires burning in Calaveras and Tuolumne County caused air quality officials to issue a smoke advisory, warning people that the air quality may be unhealthy for sensitive groups.
The TCU Lightning Complex fires have burned nearly 14,000 acres in Central California, but in a Saturday update, Cal Fire said containment was at 42%.
A vegetation fire near El Dorado Hills broke out on Labor Day, quickly growing in size and prompting evacuations, officials said.
A Sacramento County dog picked up thousands of miles from home after he went missing five years ago was reunited with his family on Wednesday.
What started as a suspicious circumstances call for Rancho Cordova police ended with a newborn surprise.
A once-empty lot behind Church of the Cross in north Modesto now hosts a thriving community garden with more than 140 plots and growers from across the globe.
A Sacramento-area middle school history and English teacher is in the running to win big as America's Favorite Teacher, a title her students think she is more than worthy of being awarded.
Junior Romello Bruhn of Woodland Christian High School is closer than ever to scoring 3,000 career points, something only 13 high school athletes have accomplished in California state history.
Folsom wins over Archbishop Riordan.
St. Mary's wins over Junipero Serra.
The Saint John's Program for Real Change has been helping women and children in Sacramento for the last four decades with housing and education.
The holiday tradition is coming with a higher price tag.
A slow start to Sierra snowfall is putting early-season pressure on Truckee businesses that rely on winter tourism, even as ski resorts race to open using man-made snow.