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Jimmy Garoppolo threw four touchdown passes, including two each to Brandon Aiyuk and George Kittle, and the San Francisco 49ers won their third straight game by blowing past the Arizona Cardinals 38-10 on Monday night in Mexico City.
San Francisco held the opposition scoreless in the second half for the second straight game.
San Francisco 49ers cornerback Jason Verrett tore his Achilles tendon during Wednesday practice, ending his season, the team revealed Thursday.
The first half of the season has been a bit of a roller coaster for the San Francisco 49ers as they try to build on last season's trip to the NFC title game.
John McVay, the executive who helped launch the San Francisco 49ers dynasty and grandfather of Rams coach Sean McVay, has died. He was 91.
The San Francisco 49ers extended their regular-season mastery over the Rams to four full years with a 31-14 victory over Los Angeles on Sunday.
San Francisco 49ers playmaker Deebo Samuel will miss Sunday's key NFC West showdown against the rival Los Angeles Rams with an injured hamstring.
Christian McCaffrey made his debut with his new squad, helping the 49ers to an early advantage but Patrick Mahomes proved the more sustainable big-play artist as the Chiefs rolled to a 44-23 win.
The San Francisco 49ers have acquired star running back Christian McCaffrey from the Carolina Panthers for a haul of draft picks.
Jimmy Garoppolo threw a little bit behind Deebo Samuel on his next-to-last possession, a fourth-and-2 from the Atlanta 19. The ball bounced off Samuel's hands and fell to the ground with 2:18 remaining.
The San Francisco 49ers beat the Carolina Panthers 37-15 on Sunday for their first road victory of the season.
A protester who ran onto the field during the San Francisco 49ers' Monday night home game against the Rams has filed a police report after being subdued by Los Angeles linebacker Bobby Wagner.
Deebo Samuel turned a short catch into an electric 57-yard touchdown, Talanoa Hufanga returned an interception for a score and the San Francisco 49ers beat the Los Angeles Rams 24-9.
At first, the San Francisco 49ers were actually relieved that Jimmy Garoppolo stepped out of his own end zone for a safety.
Veteran Dre Greenlaw, a key member of the 49ers gifted linebacker corp, has agreed to a 2-year contract extension through the 2024 season.
Trey Lance underwent season-ending surgery on his broken right ankle Monday, leaving the San Francisco 49ers to go ahead with the rest of the 2022 season with former starter Jimmy Garoppolo back in the helm.
Trey Lance suffered a season-ending broken ankle on a quarterback keeper Sunday in the first quarter of the San Francisco 49ers-Seattle Seahawks game and was replaced by former starter Jimmy Garoppolo.
San Francisco coach Kyle Shanahan announced Lance's prognosis immediately after the game.
Trey Lance got the keys to San Francisco's offense in July. When it comes to driving in the rain, well, that still needs some work.
General manager John Lynch broached the idea a few weeks ago with coach Kyle Shanahan about keeping Jimmy Garoppolo in place as the backup quarterback for the San Francisco 49ers.
The San Francisco 49ers and quarterback Jimmy Garoppolo have reportedly agreed to a restructured contract that would keep him on the team this season.
Athlete and activist Colin Kaepernick and his partner Nessa Diab announced Sunday the birth of their first child.
Nate Sudfeld led a 14-play, 79-yard drive for a go-ahead touchdown early in the fourth quarter and the San Francisco 49ers beat the Minnesota Vikings 17-7.
Nate Sudfeld led a 14-play, 79-yard drive for a go-ahead touchdown early in the fourth quarter and the 49ers beat the Vikings 17-7 on Saturday night.
San Francisco 49ers safety Jimmie Ward pulled his hamstring and might not be ready to return for the season opener on Sept. 11 in Chicago.
A Sacramento media and film training center for people with disabilities is dealing with the loss of one of its cameras after it was stolen in broad daylight.
In less than a year, Seniors on the Go in Marysville has nearly doubled in size.
One person was taken to a hospital after a car crashed into a Starbucks in Lodi on Wednesday afternoon, officials said.
FBI Deputy Director Dan Bongino will be leaving his role in January, he announced in a social media post on Wednesday.
President Trump is expected to sign an order that would reschedule marijuana to a lower drug classification, according to two sources, in one of the most significant changes to drug policy in decades.
One person was taken to a hospital after a car crashed into a Starbucks in Lodi on Wednesday afternoon, officials said.
A Sacramento media and film training center for people with disabilities is dealing with the loss of one of its cameras after it was stolen in broad daylight.
It's like a scene out of a horror movie: A fiery mystery hidden in the fog.
In less than a year, Seniors on the Go in Marysville has nearly doubled in size.
FBI Deputy Director Dan Bongino will be leaving his role in January, he announced in a social media post on Wednesday.
Sacramento police on Sunday said a thief stole a portion of a public artwork that is located in North Sacramento.
The rider of the electric unicycle was taken to the hospital with moderate injuries.
Sacramento police said the suspect was arrested by the California Highway Patrol in connection with a pursuit and firearm charges.
A man convicted of sexually assaulting a passenger on a Sacramento Regional Transit light rail train was sentenced to 35 years to life in prison, authorities said Monday.
Medical staff at the California International Marathon used a defibrillator to help a runner regain a pulse after she suffered a sudden cardiac arrest halfway through the race on Sunday.
The DMV said it is giving Tesla Motors 60 days to address its misleading use of "autopilot," or it could have its dealer license temporarily suspended.
The share of borrowers who are 30-plus days late on paying back their loans is now at 11%.
As more families in Northern California turn to charities for a helping hand this holiday season, the Salvation Army is facing one of its busiest years yet.
California's public health department said one person has died and several others have suffered severe liver damage due to eating toxic mushrooms that were foraged.
FIFA announced the match-ups and times for the six World Cup 2026 games that will be played at Levi's Stadium.
FIFA slashed the price of some World Cup tickets following a worldwide backlash, with some final seats available for $60.
Sacramento State is hiring Arizona assistant head coach and Northern California native Alonzo Carter as the next head football coach.
Julius Randle had 24 points and nine rebounds to lead Minnesota past the Sacramento Kings 117-103 in the Timberwolves' second straight game without star Anthony Edwards.
Brock Purdy threw three touchdown passes as the San Francisco 49ers beat the Tennessee Titans 37-24.
Tommy Rittenhouse threw two of his three touchdown passes to Daniel Sobkowicz, Chris Taylor returned a kickoff 91 yards for a score, and unseeded Illinois State beat UC Davis 42-31 in the quarterfinals of the FCS playoffs.
FBI Deputy Director Dan Bongino will be leaving his role in January, he announced in a social media post on Wednesday.
President Trump is expected to sign an order that would reschedule marijuana to a lower drug classification, according to two sources, in one of the most significant changes to drug policy in decades.
Stockton residents came to the last city council meeting of the year with heavy hearts, continuing to grieve and remember the lives lost of the precious children in their community.
The U.S. State Department said Clan del Golfo is a "violent and powerful criminal organization" that uses cocaine trafficking to fund violent activities.
The Lincoln councilmember made the comments during the inaugural meeting for Twelve Bridges High School's new 'Club America," a high school chapter of Charlie Kirk's Turning Point USA.
A steady stretch of nonstop fog over the last couple of weeks isn't just dampening moods, it may be taking a toll on physical health as well.
California's public health department said one person has died and several others have suffered severe liver damage due to eating toxic mushrooms that were foraged.
The plan is to embed street medicine training directly into residency programs across multiple hospitals.
Consumers with the imported pans should throw them away due to the severe health risks posed by lead, the agency warns.
Ray Cathey is on a journey from silence to new sounds. Cathey's hearing took a pounding when he was an air rescue paramedic during the Vietnam War.
Finding the perfect dress isn't easy, but now, selling them could become a lot more challenging.
This weekend, Placer County is hosting its annual Sip Into Spring event, offering free or discounted tastings at more than 20 wineries along what's known as the Placer Wine Trail.
From fruits and veggies to car parts, economists project that businesses will pass along the cost of the tariffs to customers.
An economic blackout was underway Friday as activists nationwide encouraged people not to spend their money at large corporations, retailers and fast-food chains for 24 hours.
San Joaquin County's retail theft reporting app has only been around for six months and is already bringing a sense of calmness to local business owners.
President Trump and Gov. Gavin Newsom have made several different claims about California gas prices. Here's what we found.
This year-long investigation provides an unprecedented look at California's one-party supermajority legislature through the eyes of grieving parents who discover how California lawmakers kill popular bills by not voting.
This year-long investigation by CBS News California investigative correspondent Julie Watts examines the many components of California's new tougher-on-crime law.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
The California Highway Patrol captain accused of workers' compensation fraud was the commander in charge of the fatal Mahaney Park shootout in Roseville, three officers who worked under him at the time of the shootout said.
CBS13 and the Call Kurtis consumer investigative team devised an idea on how to lower what consumers owe on their credit cards -- and it begins with a simple phone call.
No one wants to think about death. However, it's important to plan on what happens to your digital assets after you die.
After spending $18,000 on waterproof laminate floors, a Natomas couple spotted damage after the first cleaning.
More than a year after Hai Pham canceled the trial membership, he kept getting charged every month for it.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
More than two dozen structures were destroyed in a wildfire in the eastern Sierra Nevada mountains on Wednesday afternoon, officials said.
Clean-up has started in Chinese Camp after the TCU September Lightning Complex Fire ripped through the Gold Rush town earlier this month.
The fires burning in Calaveras and Tuolumne County caused air quality officials to issue a smoke advisory, warning people that the air quality may be unhealthy for sensitive groups.
The TCU Lightning Complex fires have burned nearly 14,000 acres in Central California, but in a Saturday update, Cal Fire said containment was at 42%.
A vegetation fire near El Dorado Hills broke out on Labor Day, quickly growing in size and prompting evacuations, officials said.
A Sacramento County dog picked up thousands of miles from home after he went missing five years ago was reunited with his family on Wednesday.
What started as a suspicious circumstances call for Rancho Cordova police ended with a newborn surprise.
A once-empty lot behind Church of the Cross in north Modesto now hosts a thriving community garden with more than 140 plots and growers from across the globe.
A Sacramento-area middle school history and English teacher is in the running to win big as America's Favorite Teacher, a title her students think she is more than worthy of being awarded.
Junior Romello Bruhn of Woodland Christian High School is closer than ever to scoring 3,000 career points, something only 13 high school athletes have accomplished in California state history.
Here's a look at the weather forecast Wednesday evening.
With little snowfall, skiers are hopeful snow will arrive so resorts can operate at full speed.
Esteban Reynoso reports.
The program is designed to fight isolation and it's seen so much success in Marysville that it's doubled in size.
One person was taken to a hospital after a car crashed into a Starbucks in Lodi on Wednesday afternoon, officials said.