FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
Iranian President Pezeshkian talks about proposal to reopen Strait of Hormuz
Iran's Masoud Pezeshkian says he has visited Iran's supreme leader twice and talked with CBS News' Margaret Brennan about Mojtaba Khamenei's health.
Exclusive
U.S. military lays groundwork for potential action around Cuba
Some units would "possibly [be] needed in 90-120 days," according to an internal Army message reviewed by CBS News.
OpenAI agent accessed government website data after going rogue, company reveals
The disclosure comes at a time of heightened concern over AI agents acting outside of human control.
2 American tourists dead after building explosion in Greece
The mayor of Athens said the explosion was likely caused by a gas leak.
Supreme Court again blocks Missouri's new House map that favored GOP
The Supreme Court said in an unsigned decision that ordering Missouri to restore its 2025 map "would usher in electoral chaos."
Live
Iran proposes a 7-day plan to reopen the Strait of Hormuz
Iran's president says Tehran wants a deal with the U.S. before November's midterm elections, as the regime puts an offer on the table.
Trump cancels nearly $1 billion in spending, a move some lawmakers called illegal
President Trump moved to cancel almost $1 billion in spending that was approved by Congress, marking the second time his administration has employed a rarely used tactic that some lawmakers in both parties have called illegal.
Hurricane Nolo could cause "catastrophic" flooding in Hawaii, forecasters warn
A hurricane watch is in effect for Hawaii County due to the storm, which could dump up to 3 feet of rain on Hawaii's Big Island.
Nor'easter barrels down on East Coast, threatens millions with flooding, winds
Tens of millions of people are in the path of the storm, which has already canceled concerts and prompted people on islands near Cape Cod, Massachusetts, to head to the mainland in the days ahead of the nor'easter's arrival.
U.S.
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OpenAI agent accessed government website data after going rogue, company reveals
The disclosure comes at a time of heightened concern over AI agents acting outside of human control.
TikTok settles lawsuit over youth safety concerns for at least $100 million
Alabama sued the social media company in 2025, claiming the platform had negative effects on the mental well-being of youths.
Twin doctors who grew up in poverty returned to their hometown to co-run an ER
Drs. Travan and Travis Jasper, identical twins, are co-directors of the emergency department at Chippenham Hospital in Richmond, Virginia, the city where they grew up in poverty.
Nor'easter barrels down on East Coast, threatens millions with flooding, winds
Tens of millions of people are in the path of the storm, which has already canceled concerts and prompted people on islands near Cape Cod, Massachusetts, to head to the mainland in the days ahead of the nor'easter's arrival.
Supreme Court again blocks Missouri's new House map that favored GOP
The Supreme Court said in an unsigned decision that ordering Missouri to restore its 2025 map "would usher in electoral chaos."
MoneyWatch
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TikTok settles lawsuit over youth safety concerns for at least $100 million
Alabama sued the social media company in 2025, claiming the platform had negative effects on the mental well-being of youths.
How GLP-1 weight-loss drugs are changing fast-food menus
Chipotle, McDonald's and Shake Shack are among the restaurant chains revamping their menus as more consumers go on weight-loss drugs.
Ready or not, here come the AI gadgets, from "charms" to smart speakers
Meta, Microsoft and other major tech companies are developing a range of AI products for consumers, from wearables to speakers.
Facebook found liable for deceiving users in Cambridge Analytica case
The two-week trial in New Mexico centered on accusations Facebook deceived users about a data breach.
Soaring U.S. diesel prices slam local communities as fuel costs surge
The surge in diesel prices this year is putting a financial squeeze on schools, farms and small businesses around the U.S.
Politics
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Trump cancels nearly $1 billion in spending, a move some lawmakers called illegal
President Trump moved to cancel almost $1 billion in spending that was approved by Congress, marking the second time his administration has employed a rarely used tactic that some lawmakers in both parties have called illegal.
Transcript: Iranian President Masoud Pezeshkian on "Face the Nation with Margaret Brennan"
The following is the transcript of the interview with Iranian President Masoud Pezeshkian airing on "Face the Nation with Margaret Brennan" on Sept. 27, 2026.
Iranian President Pezeshkian talks about proposal to reopen Strait of Hormuz
Iran's Masoud Pezeshkian, who is also a physician, says he has visited Iran's supreme leader twice and talked with CBS News' Margaret Brennan about Mojtaba Khamenei's health.
Supreme Court again blocks Missouri's new House map that favored GOP
The Supreme Court said in an unsigned decision that ordering Missouri to restore its 2025 map "would usher in electoral chaos."
Broadview 6 prosecutor retires under protest, blames U.S. attorney
Sheri Mecklenburg resigned from the Department of Justice this week, penning a scathing letter in which she said U.S. Attorney Andrew Boutros "personally directed" the Broadview 6 prosecution that she says ended her career.
HealthWatch
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Will an FDA crackdown curb access to cheaper GLP-1 weight-loss drugs?
The FDA has warned a major compounding pharmacy that it violated federal law by making copies of blockbuster weight-loss drugs in "inordinate amounts."
Bone health and the "silent disease": 4 things women should know
In the latest episode of "Healthful," Dr. Jocelyn Wittstein, an orthopedic surgeon at Duke University School of Medicine, discusses what women should know about protecting their bones.
Even the smallest joys can help prevent suicide, researchers say
New research highlights common themes shared by people who found reasons to keep living through dark times.
First on CBS
JB Pritzker reveals GLP-1 use, pressed on possible presidential run
Illinois Gov. JB Pritzker revealed to "CBS Mornings" that for the last two years he has been using a GLP-1 medication to lose weight.
Her son was dying, but his rare cancer made it difficult to get the right drug
As knowledge about genetics advances, some doctors say cancers should be defined by their mutations, not the tissues where they manifest.
World
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2 American tourists dead after building explosion in Greece
The mayor of Athens said the explosion was likely caused by a gas leak.
Transcript: Iranian President Masoud Pezeshkian on "Face the Nation with Margaret Brennan"
The following is the transcript of the interview with Iranian President Masoud Pezeshkian airing on "Face the Nation with Margaret Brennan" on Sept. 27, 2026.
Iranian President Pezeshkian talks about proposal to reopen Strait of Hormuz
Iran's Masoud Pezeshkian, who is also a physician, says he has visited Iran's supreme leader twice and talked with CBS News' Margaret Brennan about Mojtaba Khamenei's health.
A U.S. doctor survived a deadly strike in Gaza. Why he plans to go back.
Dr. Feroze Sidhwa was working at Nasser Hospital in Khan Younis when an Israeli strike hit the surgical unit he was in.
Ukrainian kids learn to fly drones for a future shaped by Russia's invasion
A Ukrainian nonprofit group is teaching kids to make, service and fly simple drones, to help them be "useful in the future in their country."
Entertainment
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Entertainment
2026 MTV VMAs: What to watch for
The 2026 MTV Video Music Awards will be held this weekend with Snoop Dogg carrying out hosting duties. "Entertainment Tonight" correspondent Denny Directo joins CBS News for a preview.
The New York Film Festival returns with obsessions, deceptions and monsters
Challenging documentaries and award-winning features are among the offerings of New York City's leading cinema event, starring such luminaries as Pedro Pascal, Adam Driver, Scarlett Johansson, Julianne Moore and Godzilla.
Book excerpt: "The Steps" by Sylvester Stallone
In his memoir, the actor writes of his early struggles, leading to writing his screenplay for the Oscar-winning hit "Rocky."
Ziggy Marley on dad Bob Marley's legacy
Jamaican musician Ziggy Marley shares memories of his father, Bob Marley, and discusses his new children's book, "True to Myself."
Jane Doe who accused Jay-Z of sexual assault formally recants her claims
The anonymous woman who accused Jay-Z of sexually assaulting her said in a new court filing that she never met the rap mogul.
Technology
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TikTok settles lawsuit over youth safety concerns for at least $100 million
Alabama sued the social media company in 2025, claiming the platform had negative effects on the mental well-being of youths.
Court sides with Pentagon in Anthropic case
The growing concerns over the safety of artificial intelligence and the speed of its development have many calling for government regulation. Recently, President Trump said he plans to appoint an adviser and create an AI force. J.B. Branch, director of federal AI governance and technology policy at Public Citizen, joins CBS News to discuss.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
Takeaways as Xi wraps state visit with Trump
Chinese President Xi Jinping's state visit to the U.S. wrapped up on Friday, with no deal announced on artificial intelligence, though he is set to meet with President Trump twice more before the end of the year. Weijia Jiang has more.
Software developer on the AI alignment problem
News broke this week that a rogue artificial intelligence agent hacked Australia's health care database, and no notice was given for months. Matt Calkins, CEO and co-founder of Appian, which develops software to maximize AI integration, joins to unpack the week's AI headlines.
Science
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Science
Neuroscientists grow human brain tissue in mice
Neuroscientists at Stanford University successfully grew human brain tissue inside mice in the hopes of further enabling the development of treatments for brain disorders. Stanford Medicine professor of psychiatry and behavioral sciences Dr. Sergiu Pasca, who led the study, joins CBS News to break down the findings.
New species of wild cat discovered for first time in more than a century
Scientists have discovered a new species of wild cat for the first time in more than a century, a Bolivian researcher says.
Humpback whale seen grieving dead calf in rare footage
The footage shows a female humpback whale staying close to the dead calf as it lies motionless on the seafloor, touching it with its head and fin.
Remains of ancient warhorse given honorific burial discovered in Egypt
Archaeologists say they've discovered the remains of a likely ancient Egyptian warhorse given an honorific burial more than 3,000 years ago.
Anthropic CEO says "exponential" growth of AI is a "warning sign"
Artificial intelligence technology is developing at an "exponential" rate, Anthropic CEO Dario Amodei told CBS News, calling the situation a "warning sign" for the industry that requires serious safeguards.
Crime
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Tasia Fortune's hanging was "staged" after her death, police say
Authorities haven't disclosed the exact cause of Fortune's death, but they did rule it a homicide and have arrested two men.
Latest in trial of "American Idol" contestant
Former "American Idol" contestant and music pastor Caleb Flynn stands accused of murdering his wife. His former mistress, Alleigha Botner, testified in the trial. CBS News' Ian Lee has more details.
Minnesota sailor returns from USS Lincoln duty to find apartment ransacked
A Minnesota native who had been serving aboard the USS Abraham Lincoln for nearly 10 months came home to an upsetting surprise.
Pittsburgh doctor killed while he slept remembered as "a true angel on Earth"
Dr. Idris Evans, the Pittsburgh doctor killed in a violent home invasion, is being remembered for his kindness and compassion.
"American Idol" alum's ex-mistress testifies
Former "American Idol" contestant Caleb Flynn is on trial for allegedly killing his wife and staging an elaborate crime scene. Flynn's former mistress testified at the trial. Ian Lee has the latest details.
Space
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NASA spacecraft discovers moon crater bigger than Roman Colosseum
Scientists have discovered a crater on the moon that's bigger than the Roman Colosseum, the result of a powerful impact two years ago.
NASA launches its Roman Space Telescope to explore the hidden universe
NASA's Roman Space Telescope launched shortly after daybreak from Kennedy Space Center and blazed toward an observation point 1 million miles away.
Roman Space Telescope promises 300-megapixel views of the cosmos
The $4.3 billion telescope is expected to discover tens of thousands of exoplanets while probing the nature of mysterious dark matter and energy.
First on CBS
Trump to honor Artemis II crew with nation's top space medal
President Trump plans to award the Congressional Space Medal of Honor to the crew of NASA's Artemis II mission in a ceremony Aug. 28.
NASA's Swift telescope will plunge toward Earth after rescue mission called off
The mission to save NASA's sinking space telescope has been called off, dooming the telescope to a fiery reentry later this year.
Latest Galleries
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Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Dolly Parton: An extraordinary life in pictures
Dolly Parton, the country music legend who became a feminist icon, has died at the age of 80. Here is a look back at her life in pictures.
Investigating the death of designer Sylvie Cachay
Sylvie Cachay was found dead in an overflowing bathtub at the exclusive Soho House in New York City on Dec. 9, 2010. A water leak at the hotel gave away a timeline that may have revealed her killer.
Summer music highlights of 2026
Summer is the time to enjoy live music, indoors and out. Scroll through our gallery of some of 2026's leading musical acts, featuring images by CBS News photojournalist Jake Barlow and photographers Ed Spinelli and Kirstine Walton.
Photos show celebrations at Obama Presidential Center
The Obama Presidential Center, museum and library opens in Chicago with a star-studded grand opening ceremony and public watch party on Midway Plaisance.
Latest CBS News Videos
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Latest CBS News Videos
Extended interview: Patrick Clancy
Patrick Clancy wrestles with grief and shares memories of his children in his first interview since his ex-wife Lindsay Clancy's murder trial ended without a verdict.
9/25: CBS Evening News
Over 60 million in danger from Nor'easter; Hawaiians shelter ahead of Hurricane Nolo.
2026 MTV VMAs: What to watch for
The 2026 MTV Video Music Awards will be held this weekend with Snoop Dogg carrying out hosting duties. "Entertainment Tonight" correspondent Denny Directo joins CBS News for a preview.
How El Niño is supercharging Pacific storms
While El Niño is a natural shift in the climate system, scientists say the weather pattern developing in the Pacific Ocean could be one of the strongest on record. And human-caused climate change is super-charging its strength, making weather extremes worse. Tracy Wholf, founder of WereWHOLF Media, joins CBS News to discuss.
Extended interview: Masoud Pezeshkian
Iranian President Masoud Pezeshkian speaks with Face the Nation's Margaret Brennan about the war with the U.S., his country's latest offer to open the Strait of Hormuz, the supreme leader's condition and more.