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After scoring 10 points in the past two games combined, the 49er offense finally woke up. Frank Gore and Anquan Boldin lead the way as San Francisco snapped their first losing streak under Jim Harbaugh, exacting revenge on a St. Louis team that had the 49ers number last season.
Colin Kaepernick threw two touchdown passes, Frank Gore had his first 100-yard game of the season and the San Francisco 49ers' defense stepped up without some of their stars in a 35-11 rout over the St. Louis Rams on Thursday night.
Linebacker Patrick Willis and cornerback Nnamdi Asomugha were inactive for the San Francisco 49ers against the St. Louis Rams on Thursday evening.
The struggling 49ers face the Rams in St. Louis Thursday night.
Mired in their first losing stretch under coach Jim Harbaugh and minus at least one key player, the visiting 49ers look to avoid a third consecutive defeat Thursday night against a Rams team that gave them plenty of trouble in 2012.
"We're facing adversity. It gives us the opportunity to stare it in the face and respond," 49ers head coach Jim Harbaugh said. "That's a relentless quest for improvement, that's where we're at."
While it's hard to tell, the 49ers are slowly getting healthier. The long list of names on their injured report remains, but nothing to be alarmed about for the time being. St. Louis on the other hand is as healthy as can be heading into this pivotal game to stay out of the NFC West cellar.
One-fourth of the season will be over by the time the 49ers walk off the field in St. Louis, and if they do it as a 1-3 team, they will have dug themselves a hole that will be awfully hard to climb out from.
On their way to the Super Bowl last season, the San Francisco 49ers couldn't solve one team: the Rams. St. Louis beat San Francisco once and the teams played to a tie, rare blemishes on the 49ers' record.
In Week 1, San Francisco 49ers quarterback Colin Kaepernick set the world on fire with his passing against the Green Packers, throwing for 421 yards and basically convincing everyone he's the greatest quarterback in NFL history. The last two weeks? Yeah not so much.
While noting the 49ers lost to two very good teams in the Seahawks and Colts the last two weeks, Madden said those games exposed another 49er weakness.
With the 49ers sputtering out to a 1-2 start in 2013, everyone is trying to figure out what is wrong with the team many had picked to be the NFC representative in the Super bowl. While most theories are around the offense that has failed to put up points, the real concern is a 49ers defense that is running out of bodies.
While everybody in the 49ers locker room is rooting for Aldon Smith's recovery in rehab, his fellow defenders are now focused on getting the most from the guys who will take over for him: Dan Skuta and Corey Lemonier, among others.
A teenage football fan suffered a concussion and a broken arm and nose at Candlestick Park after police say he was assaulted at the San Francisco 49ers game.
Despite the multitude of issues surrounding the 49ers, they will still have the better team on the field Thursday Night, and if they play like they can, they will snap their first losing streak under Jim Harbaugh as well as their losing streak to the St. Louis Rams.
The NBA game between the Minnesota Timberwolves and Golden State Warriors has been postponed following another fatal shooting by federal immigration officers in Minneapolis.
One-time NFL MVP and longtime San Francisco 49ers quarterback John Brodie has died at the age of 90.
Kevin Johnson died from "blunt head trauma and stab wounds" at a homeless encampment, the Los Angeles County Medical Examiner said.
Ryan Wedding, a 44-year-old Canadian national, was added to the FBI's Ten Most Wanted Fugitives list last year.
San Francisco Giants outfielder Jung Hoo Lee was detained by Customs and Border Protection agents at LAX on Wednesday.
Buster Posey is expected to be the top newcomer on baseball's 2027 Hall of Fame ballot.
Carlos Beltrán was a nine-time All-Star during his 20-year MLB career. Andruw Jones was a five-time All-Star and won 10 Gold Gloves.
Golden State — with about two weeks until the trade deadline — will have decisions to make about how to attack the remainder of the season without Jimmy Butler.
The Tennessee Titans have agreed to hire Robert Saleh as their coach, hoping he can speed up their rebuild and end the franchise's skid of four straight losing seasons.
At the end of this school year, all high school sports coaches and their assistants will be fired, with an option to reapply for their old jobs. The district says it's a new Human Resources policy, but to the coaches and team supporters, it feels like an insult.
The NBA game between the Minnesota Timberwolves and Golden State Warriors has been postponed following another fatal shooting by federal immigration officers in Minneapolis.
A man is dead after a shooting in Minneapolis on Saturday involving federal immigration agents from Customs and Border Protection. Here's what we know so far.
U.S. District Court Judge Eric Tostrud granted a temporary restraining order against the U.S. Department of Homeland Security Saturday, barring the department from altering or destroying evidence in the killing of Alex Pretti in south Minneapolis.
More than 230 million people are under winter storm threats as officials brace for power outages and travel difficulties.
The NBA game between the Minnesota Timberwolves and Golden State Warriors has been postponed following another fatal shooting by federal immigration officers in Minneapolis.
At the Clift Royal Sonesta Hotel, history is not only preserved but also shared through a new speaker series aimed at bringing San Francisco's past to life.
San Francisco's North Beach is home to wonderful Italian food and pastries. It attracts locals and tourists to the area to check out world-famous pizza, but that has caused somewhat of a problem.
One major development is finished, which brought 50 new units to the coast for farmworkers.
San Francisco Mayor Daniel Lurie has teamed up with a state lawmaker in seeking a new law that would toughen penalties on sideshows across California.
At the end of this school year, all high school sports coaches and their assistants will be fired, with an option to reapply for their old jobs. The district says it's a new Human Resources policy, but to the coaches and team supporters, it feels like an insult.
With a new California law that lifts restrictions on the types of businesses to lease from Jack London Square, many Oakland business owners hope that new doors of opportunity could open for them.
Getting up before sunrise when it's dark and 39 degrees isn't most people's idea of motivation, but for a growing group of Bay Area runners, it turns out that a little community goes a long way.
More than a decade after an Antioch woman was killed, her husband has been charged with her murder, prosecutors said.
Police in Antioch have launched a suspicious death investigation after a person found lying on a roadway early Friday morning died.
Step inside the Seymour Marine Research Center at the University of California at Santa Cruz and be prepared to be "swallowed up" by a whale of a tale.
The Monterey County District Attorney's Office released preliminary information and body camera footage of a fatal shooting by police in Marina on Sunday, saying the man killed by officers was armed with a loaded handgun.
An arsonist is on the loose in San Jose, and investigators are looking to see if he may be responsible for burning seven cars at five different locations.
Police in San Jose provided an update into a deadly shootout with an armed suspect on Wednesday, saying he took part in a multi-day crime spree that involved multiple armed robberies, carjackings and shootings with law enforcement.
Authorities in Santa Cruz County said they have arrested a juvenile in connection with an altercation near Aptos High School as they continue to investigate the recent discovery of a gun and ammunition on campus.
Health officials in Napa County confirmed Wednesday that a child has been diagnosed with measles in the county's first case in nearly 15 years.
Audrey Hitchcock owns Ramini Mozzarella, a line of authentic cheeses made from the milk of water buffaloes.
The Vallejo Police Department said it will receive additional patrol support from Solano County sheriff's deputies through the end of 2026, as the department deals with staffing shortages.
The county says the levee was structurally damaged by the large tidal pressure, sustaining an estimated $2.6 million in damage.
Authorities in the North Bay said they arrested a wanted felon after he allegedly stole a food delivery driver's vehicle and led police on a pursuit over the weekend.
The NBA game between the Minnesota Timberwolves and Golden State Warriors has been postponed following another fatal shooting by federal immigration officers in Minneapolis.
One-time NFL MVP and longtime San Francisco 49ers quarterback John Brodie has died at the age of 90.
Kevin Johnson died from "blunt head trauma and stab wounds" at a homeless encampment, the Los Angeles County Medical Examiner said.
Ryan Wedding, a 44-year-old Canadian national, was added to the FBI's Ten Most Wanted Fugitives list last year.
San Francisco Giants outfielder Jung Hoo Lee was detained by Customs and Border Protection agents at LAX on Wednesday.
More than a decade after an Antioch woman was killed, her husband has been charged with her murder, prosecutors said.
San Francisco Mayor Daniel Lurie has teamed up with a state lawmaker in seeking a new law that would toughen penalties on sideshows across California.
Police in Antioch have launched a suspicious death investigation after a person found lying on a roadway early Friday morning died.
The Monterey County District Attorney's Office released preliminary information and body camera footage of a fatal shooting by police in Marina on Sunday, saying the man killed by officers was armed with a loaded handgun.
Ryan Wedding, a 44-year-old Canadian national, was added to the FBI's Ten Most Wanted Fugitives list last year.
Microsoft services were down for thousands of users, according to tracking service Downdetector.
The billionaire CEO of Tesla and SpaceX, in his first appearance at Davos, said Tesla could start selling its Optimus robots next year.
BART riders will be able to book short Uber rides to and from stations through the agency's app, under a partnership announced Tuesday.
Verizon says it's giving a $20 credit to customers affected an outage that disrupted service across the U.S.
Grok faces mounting scrutiny from government officials and advocacy groups after people used the AI chatbot to create sexualized images of minors and women.
Health officials in Napa County confirmed Wednesday that a child has been diagnosed with measles in the county's first case in nearly 15 years.
Over the years, Dr. Rachel Forer has found plenty of ways to take the sting out of going to the dentist. But no matter how hard she tried, fear had a way of creeping in.
Officials in San Mateo County are the latest in the Bay Area to warn residents to not forage for wild mushrooms, amid a rise in mushroom poisonings that have led to illnesses and even deaths.
The Bay Area's Spare the Air alert has been extended to at least Saturday as a high-pressure system is expected to hang around and impact air quality.
Kaiser Permanente has reached a lawsuit settlement over alleged patient data breaches involving Kaiser websites and mobile applications, with members eligible to receive a payment from a $46 million settlement fund, the health care giant announced.
San Francisco Mayor Daniel Lurie has teamed up with a state lawmaker in seeking a new law that would toughen penalties on sideshows across California.
A federal judge says the Trump administration must keep the money flowing for now for programs aimed at helping low-income families with children in five states.
A year ago, a law that effectively banned TikTok in the U.S. went into effect, though President Trump has not enforced it.
School district officials in Columbia Heights, Minnesota, say their sense of security is shaken and their hearts shattered after four students from the district have recently been taken by officers with Immigration and Customs Enforcement.
ICE authorized its officers to enter homes without judicial warrants in the cases of people with deportation orders, a sweeping reversal of longstanding rules, according to a whistleblower complaint.
The billionaire and philanthropist MacKenzie Scott donated $45 million to The Trevor Project, a nonprofit focused on suicide prevention and advocacy for LGBTQ young people.
Oasis nightclub announced plans to close six months ago. New Year's Eve was slated for the final performance. A last-minute, multi-million dollar donation turned the final curtain call into an encore performance.
A 16-year FBI employee has filed a lawsuit alleging he was fired last month because he had a Pride flag displayed near his desk.
A group of transgender members of the U.S. Air Force and Space Force forced to leave active duty under the Trump administration's policies say their benefits were revoked in a rare move.
California state Sen. Scott Wiener of San Francisco announced Wednesday that he is running for Nancy Pelosi's congressional seat next year.
The nominees for the 98th annual Academy Awards were announced Thursday morning, and though "One Battle After Another," "Marty Supreme," "Frankenstein" and "Hamnet" were all nominated for plenty, it was "Sinners" that broke through with a record-smashing 16 nominations.
The 2026 Songwriters Hall of Fame inductees were revealed on "CBS Mornings" on Wednesday. See the full list.
The two-story H Mart will be at Pacific Commons Shopping Center in Fremont, and construction is planned for late 2026. In addition to its grocery selections, it will have a food hall, with a variety of fast-casual eateries, restaurants, a bar and entertainment offerings.
The National Football League will kick off Super Bowl LX with an opening ceremony performance by hometown rock legends Green Day as part of the festivities at Levi's Stadium in Santa Clara, the league announced Sunday.
The original member of the Grateful Dead had tirelessly carried on the band's music for three decades, and on Saturday, the City of San Francisco said goodbye in a public memorial called The Homecoming.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Fire crews responded to Exeter Street Saturday night for a two-alarm fire.
Here's a look at the weather forecast Saturday evening.
The high school community in the East Bay city of Newark is in an uproar as a result of a new policy by the local school district.
with Zoe Mintz.
At the Clift Royal Sonesta Hotel, history is not only preserved but also shared through a new speaker series aimed at bringing San Francisco's past to life.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
