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An estimated one in eight women will develop breast cancer in their lifetime, killing on average 42,000 a year in the U.S. But what if a vaccine could significantly lower each woman's chance of ever getting it in the first place?
Jewish organizations in Pittsburgh marked the first night of Hanukkah amid the war in Israel and a surge in antisemitism.
Hunter Biden, the son of President Joe Biden, was indicted in the Central District of California Thursday.
This troupe of performers is getting a lot of attention lately.
All of their chocolate is made fresh from scratch, mostly in their Canonsburg facility.
A herd of cattle has found its way into a Mars neighborhood and residents say it's been an ongoing problem.
Pennsylvania Gov. Josh Shapiro is reviewing his first year in office.
It's a Pittsburgh business with 123 years of history, but Carl Herrmann Furs feels targeted.
A crash involving nine cars inside the Liberty Tunnel sent six people to the hospital, including one in critical condition.
In today's Talk Pittsburgh PTL Advent Calendar Crossover, we're showing you how you can celebrate the holidays with some holly jolly drinks. We were joined by Kelly Giger and Marc Yacoviello from The Industrialist Hotel.
Coming up on Talk Pittsburgh (12/7)
A former Pennsylvania State Police corporal has been sentenced to 23 years in prison on child sexual exploitation charges.
Leaders said donations and any other forms of assistance are appreciated.
A West Mifflin firefighter is accused of sexually assaulting two teenage girls at the fire station.
Police executed a search warrant at the home of Washington County Controller April Sloane after her dog died.
Pittsburgh City Council on Sunday approved a 20% tax increase as part of the city's 2026 budget, sending it to Mayor Ed Gainey's desk. KDKA-TV's Ricky Sayer reports.
A woman has died, and a man is in critical condition after a shooting in McKeesport, Allegheny County police said Sunday night. KDKA-TV's Ricky Sayer has more.
During the holidays, many families find themselves with a child in the hospital, but thanks to the Ronald McDonald House, they find comfort. KDKA's Megan Shinn tells their story in the KD Sunday Spotlight.
Joey Porter Sr., Joey Porter Jr., and Jerome Bettis were on hand to hand out gifts to children in Sheraden on Saturday afternoon.
Stay on top of local weather with meteorologist Mary Ours’s forecast!
United Airlines Flight 93 crashed near Shanksville, Pennsylvania, during the terrorist attacks of Sept. 11, 2001.
People gathered at the Flight 93 National Memorial to remember those who died 25 years ago while thwarting a terrorist attack.
While many had never heard of Shanksville before Sept. 11, 2001, 25 years later, their acts of service remain.
Mike McCarthy and Kevin Stefanski are starting new chapters with their teams as the 2026 season opens.
Damon Ferguson Jr. scored a touchdown and Pittsburgh's defense held on to beat UCF 12-7 on Saturday.
Sen. John Fetterman's surprise video introducing Sen. Dave McCormick at the Republican Party's midterm convention sparked a strong reaction from Democrats. KDKA political analyst Jon Delano breaks it down.
Sen. John Fetterman's surprise video at the Republican Party's midterm convention sparked a strong reaction from Democrats.
Democratic Sen. John Fetterman appeared in a surprise video at the Republican Party's midterm convention on Wednesday, as he becomes increasingly isolated from his own party.
A Pennsylvania man is facing charges after police said he called Gov. Josh Shapiro's office and threatened to "destroy the Commonwealth."
The Trump administration moved Tuesday to ban imports of Canadian motorcycles, some dairy products and most types of alcohol starting later this month, intensifying the trade war between the two countries.
It seems like each week we get a new story or warning about a scam over the phone or on the internet. Here's how you can avoid them.
With proposed 50% tariffs on the table, the cost of new and used cars could increase by thousands in the near future.
A new report tries to calculate how much Pennsylvanians need to earn to live what's considered a comfortable lifestyle.
The store is expected to open sometime next year.
Buffalo Township police are warning about scammers after investigating several cases where residents have fallen victim.
Get your tickets now for the PTL Turkey Fund Kickoff Show happening at the Pittsburgh Playhouse on Sept. 18!
The Original Pittsburgh Taco Festival is back with over 25 food trucks and authentic Latin music. It takes place Saturday, Sept. 12, at The Stacks at 3 Crossings in the Strip District.
Daisy checks out Gameway, the new video gaming lounge at Pittsburgh International Airport!
Leechburg Pizza Company is the latest pizza place featured on PTL Pizza Friday!
The Pittsburgh County Fair will take place Saturday, Sept. 12, at Allegheny Commons Park West. It's a celebration of urban agriculture and all things handmade, homemade, and delicious in Pittsburgh.
The Steel City Youth Football League announced disciplinary action following video that captured an on-field brawl.
Misdemeanor and summary charges have been filed against the coaches involved in a youth football brawl in Pittsburgh.
Police departments all around the country say surveillance technologies like cameras, drones, and license plate readers have proved invaluable in tracking and arresting violent criminals.
Video shows youth football coaches from Carlynton and Keystone Oaks fighting on the field during a game over the weekend.
Police public safety services are being questioned in Forward Township.
Four vaccinated people in Pennsylvania have contracted measles, health officials say.
A Pittsburgh-area hospital is seeing a concerning uptick in withdrawals from what many describe as "gas station heroin."
Mental health days aren't just for adults; oftentimes, children need them, too, so here's what parents need to be on the lookout for.
Getting zapped by lightning is an enormous danger, and with an uptick in strikes in the Pittsburgh area, here's what you need to know.
A Pittsburgh-area mother is sharing her story after she says her daughter was exposed to measles at UPMC Children's Hospital.
Mike McCarthy and Kevin Stefanski are starting new chapters with their teams as the 2026 season opens.
Damon Ferguson Jr. scored a touchdown and Pittsburgh's defense held on to beat UCF 12-7 on Saturday.
The Cubs won their second straight as the Pirates dropped a second straight after winning nine of 11.
West Virginia is 2-0 for the first time since 2018 after a 52-7 win over UT Martin.
Rocco Becht threw for 268 yards and three touchdowns, leading No. 16 Penn State to a 27-9 victory over Temple.
Many small businesses are still feeling the impact of last week's severe weather.
Pittsburgh leaders and their partners are making a concerted effort to revitalize a North Side business district.
A federally funded Ohio manufacturing program faces potential shutdown after a new audit by the U.S. Department of Commerce's Office of Inspector General.
Gas station giant Buc-ee's has sparked a backlash in Ohio over one of its frequent trademark infringement lawsuits.
The international fashion retailer Zara will open a location in Ross Park Mall in 2028, as the mall continues to thrive.
Local legend Donnie Iris will headline an early show at Pittsburgh's newest music venue, Citizens Live at The Wylie.
Dolly Parton died in Nashville on Aug. 25 at the age of 80 — a shock to fans around the world who weren't aware of her illness.
A show coming to The Palace Theatre in Greensburg looks to pay tribute to Dolly Parton.
Tim Curry was known for his iconic performances in cult classics like "The Rocky Horror Picture Show" and the original screen adaptation of Stephen King's "It."
Pittsburghers are remembering Dolly Parton as "one of a kind" following her death on Tuesday.
Watch as teams from Homer Center, Pine-Richland, and Quaker Valley high schools compete on this edition of KD Quiz!
Watch as teams from Homer Center, Pine-Richland, and Quaker Valley high schools compete on this edition of KD Quiz!
Watch as teams from Homer Center, Pine-Richland, and Quaker Valley high schools compete on this edition of KD Quiz!
Watch as teams from Homer Center, Pine-Richland, and Quaker Valley high schools compete on this edition of KD Quiz!
Have you ever noticed that thunder sounds louder at night? Ray Petelin explains why in a new Hey Ray!
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
