FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
House adopts Senate-approved budget resolution to unlock ICE funding
The budget blueprint is the first step in Republicans' two-pronged plan to end the Department of Homeland Security shutdown.
Live
U.S. carrier in Iran war set to leave in days as official reveals conflict's cost
The USS Gerald R. Ford aircraft carrier is expected to leave the Middle East in the coming days, a U.S. official confirmed to CBS News.
Secret Service officer shot at gala was not hit by friendly fire, sources say
Federal investigators have also determined that the suspected gunman, 31-year-old Cole Allen, fired his shotgun, the sources said.
Supreme Court weakens Voting Rights Act, voiding Louisiana congressional map
The Supreme Court rule 6-3 in a decision that has implications for the scope of the landmark Voting Rights Act.
Trump says U.S. may cut the number of American troops in Germany
President Trump said Wednesday he is considering reducing the number of U.S. forces in Germany, amid a spat with Germany's chancellor and the NATO alliance over Iran.
Iran war has cost $25 billion to date, defense official says
The war with Iran is now in its ninth week, and Congress is concerned about the reduction of global munition stockpiles and the ability to restock them.
Comey appears in court after his indictment for allegedly threatening Trump
Former FBI Director James Comey was indicted Tuesday for allegedly making threats against President Trump.
King Charles III, Queen Camilla visit New York City
As part of his four-day trip to the U.S. to commemorate America's 250th birthday, King Charles III took part in a series of events in New York City.
Investigation
How a company likened to a sex cult is lobbying Trump for pardons
OneTaste, a company in San Francisco that prosecutors likened to a sex cult, has embarked on a campaign to court allies of President Trump as it seeks pardons for its two convicted leaders, CBS News has learned.
U.S.
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OpenAI sued by families of school shooting victims in Canada's Tumbler Ridge
Several families of victims of a mass shooting in Canada are suing OpenAI and its CEO, Sam Altman, alleging the company's generative AI chatbot, ChatGPT, played a role in the February shooting.
U.S. charges 10 Mexican officials, including Sinaloa governor, with drug trafficking
The U.S. government has charged the governor of Mexico's Sinaloa state and nine other current and former Mexican officials with drug trafficking and weapons offenses in a federal indictment.
Elon Musk tells court he was a "fool" for funding OpenAI
Elon Musk alleges that OpenAI reneged on a promise to operate as a nonprofit dedicated to human progress.
Ford to receive $1.3 billion government refund for Trump's IEEPA tariffs
Detroit automaker expects big financial boost from refund of tariffs struck down earlier this year by the Supreme Court.
Secret Service officer shot at gala was not hit by friendly fire, sources say
Federal investigators have also determined that the suspected gunman, 31-year-old Cole Allen, fired his shotgun, the sources said.
MoneyWatch
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Elon Musk tells court he was a "fool" for funding OpenAI
Elon Musk alleges that OpenAI reneged on a promise to operate as a nonprofit dedicated to human progress.
Ford to receive $1.3 billion government refund for Trump's IEEPA tariffs
Detroit automaker expects big financial boost from refund of tariffs struck down earlier this year by the Supreme Court.
Talks to bail out Spirit Airlines stall as company teeters toward collapse
Spirit Airlines only has enough available cash to continue operations for a matter of days, not weeks, and talks for a government-backed rescue of the no-frills carrier have stalled, sources say.
Powell to stay on Federal Reserve board as policy makers hold rates steady
Fed chief Jerome Powell said he will remain as a governor on the central bank's board after his term as chair ends on May 15.
TSA PreCheck offers discount to younger travelers. Here's what to know.
TSA is trying to encourage young travelers to enroll in its PreCheck program before summer travel kicks off.
Politics
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House adopts Senate-approved budget resolution to unlock ICE funding
The budget blueprint is the first step in Republicans' two-pronged plan to end the Department of Homeland Security shutdown.
In crowded CA gubernatorial debate, Democrats spar while Republicans blame incumbents
The primary election in California's gubernatorial contest is just over a month away, and the race remains wide open.
U.S. charges 10 Mexican officials, including Sinaloa governor, with drug trafficking
The U.S. government has charged the governor of Mexico's Sinaloa state and nine other current and former Mexican officials with drug trafficking and weapons offenses in a federal indictment.
Trump says U.S. may cut the number of American troops in Germany
President Trump said Wednesday he is considering reducing the number of U.S. forces in Germany, amid a spat with Germany's chancellor and the NATO alliance over Iran.
Secret Service officer shot at gala was not hit by friendly fire, sources say
Federal investigators have also determined that the suspected gunman, 31-year-old Cole Allen, fired his shotgun, the sources said.
HealthWatch
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Beyond crisis lines: How broader suicide prevention helps people in need
A new approach to suicide prevention shifts the focus from stopping harm in moments of crisis to upstream policies that give people reasons to live.
Big companies position themselves for payday from $50B federal rural health fund
A $50 billion federal fund is supposed to modernize rural healthcare. But community clinics and advocates fear that the contractors administering the money for states will bite off a big chunk before it reaches patients.
A 13-year-old's kidney was failing. Then a stranger stepped in.
Tim Fitzpatrick, a father of a chronically ill child, saw the story of a boy in need of a new kidney and felt compelled to help.
Ben Sasse is on extended time. He credits "providence, prayer and a miracle drug."
The former U.S. senator from Nebraska opened up about his terminal diagnosis, his family and the state of American politics in a "Things That Matter" town hall.
Exclusive
Johnson & Johnson to launch on TrumpRx with 4 of its prescription drugs
Drug-making giant Johnson & Johnson will officially start marketing four of its medications on the Trump administration's TrumpRx website on Friday, CBS News exclusively learned.
World
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U.S. charges 10 Mexican officials, including Sinaloa governor, with drug trafficking
The U.S. government has charged the governor of Mexico's Sinaloa state and nine other current and former Mexican officials with drug trafficking and weapons offenses in a federal indictment.
Trump says U.S. may cut the number of American troops in Germany
President Trump said Wednesday he is considering reducing the number of U.S. forces in Germany, amid a spat with Germany's chancellor and the NATO alliance over Iran.
How Ukraine's demining robots could help U.S. open the Strait of Hormuz
Ukraine has perfected demining techniques in the Black Sea over four years of war against Russia.
Robot exploring France's deepest shipwreck finds cannons, ceramics
An army survey of the seabed uncovered the 16th-century merchant ship by chance in waters off the coast of France.
From a brooch to the queen's iPod: A history of gifts between U.S. and U.K.
King Charles surprised President Trump with the bell from the HMS Trump, a World War II-era British submarine, during this week's visit.
Entertainment
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Entertainment
Wilmer Valderrama on his 200th "NCIS" episode
As "NCIS" nears the highly-anticipated finale of season 23, it will also be star Wilmer Valderama's 200th episode on the show. He reflects on his time on the series and reveals the season finale will have "a lot of danger," adding, "we're setting a crazy tone for next season."
Reshaping the conversation about aging
Constance Zimmer, who co-hosts the podcast "Talk 50 to Me," talks about reframing the conversation among women about aging. The podcast features interviews with women in their 50s, talking about the realities of midlife.
FCC orders review of ABC broadcast licenses
The FCC has ordered an early review of the broadcast licenses for eight local stations owned by ABC. The move comes after President Trump and first lady Melania Trump demanded ABC fire late-night host Jimmy Kimmel. Ed O'Keefe reports.
FCC reviewing ABC licenses amid Kimmel feud
The Federal Communications Commission says it wants the Walt Disney Company to file for early license renewal for its television stations. The announcement comes one day after President Trump and the first lady called on ABC to fire late-night host Jimmy Kimmel. CBS News legal contributor Rebecca Roiphe joins with analysis.
FCC reviewing Disney licenses over DEI practices
One day after President Trump called on ABC to fire late-night host Jimmy Kimmel, the FCC said it will begin reviewing eight broadcasting licenses owned or managed by Disney due to the company's diversity policies. CBS News senior White House and political correspondent Ed O'Keefe has the latest.
Technology
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Technology
Tech companies post earnings amid bubble concerns
Four of the biggest tech companies reported earnings after the closing bell on Wednesday. Adam Levine, senior tech writer for Barron's, joins CBS News to discuss.
Elon Musk tells court he was a "fool" for funding OpenAI
Elon Musk alleges that OpenAI reneged on a promise to operate as a nonprofit dedicated to human progress.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
Comparing popular smartwatches right now
Smartwatches can measure everything from heart rate to step count, but which features are most accurate and are worth using? Vanessa Hand Orellana, CNET's lead wearable tech reporter, joins CBS News to discuss.
Musk testifies for 2nd day in OpenAI trial
Elon Musk testified for a second day on Wednesday in a trial that's pitting two tech titans against each other. Paresh Dave, senior writer at Wired, joins CBS News to discuss.
Science
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Trump administration fires board overseeing National Science Foundation
The Trump administration has fired all 22 current members of an independent board that oversees the National Science Foundation, one dismissed member says.
AI used to reveal face of victim fleeing Mount Vesuvius eruption
Archaeologists found the victim holding a terracotta mortar, which they interpret as an improvised attempt to shield his head.
In a first, endangered orangutan seen using canopy bridge to cross road
Rapid development has been shrinking the jungle habitat of the critically endangered species, and fatal conflicts with people have been increasing.
Saving the Venus fly trap
The carnivorous Venus fly trap is native to the Carolinas, but its population is dwindling due to loss of habitat. Correspondent Seth Doane talks with botanist Julie Moore, who has spent much of her life helping to save these remarkable plants; and with Damon Waitt, director of the North Carolina Botanical Garden, who discusses the unusual traits of a species that Charles Darwin called the most interesting plant in the world.
From 1990: NASA launches Hubble Telescope
On April 24, 1990, NASA launched the Hubble Space Telescope from the Space Shuttle Discovery after seven years of delays. Watch CBS News' coverage from that day.
Crime
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Crime
New details on D.C. press dinner shooting
The Justice Department released a photo allegedly showing the suspect in the White House Correspondents' Dinner shooting, roughly 30 minutes before he rushed past security at the event. CBS News' Sam Vinograd has more.
Prosecutors allege D4vd killed teen to silence her
Prosecutors on Wednesday alleged singer D4vd killed Celeste Rivas Hernandez to silence her "before she ruined his music career." CBS News Los Angeles reporter Hunter Sowards has the latest.
Nick Reiner appears in court
Nick Reiner appeared in a Los Angeles courtroom on Wednesday, several weeks after pleading not guilty in the grisly death of his famous parents, Rob and Michelle Reiner. Carter Evans has more details.
New evidence released in D.C. shooting
Cole Allen, the man accused of trying to assassinate President Trump at the White House Correspondents' Dinner on Saturday, took a mirror selfie, allegedly gearing up for battle, officials said. Matt Gutman reports.
James Comey makes court appearance
Former FBI Director James Comey made his first court appearance in Virginia on Wednesday, charged with threatening President Trump. A grand jury indicted Comey yesterday over a social media post he made last year. CBS News Department of Justice reporter Jake Rosen has more.
Space
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SpaceX launches Falcon Heavy rocket carrying powerful satellite
SpaceX's most powerful operational rocket boosted a high-speed ViaSat internet data relay satellite into space to complete a globe-spanning constellation.
Mars rover carries out chemistry experiment never done beyond Earth
"This experiment's never been run before on another world," said Amy Williams, an astrobiologist working on the Curiosity mission.
Blue Origin New Glenn rocket puts satellite payload into wrong orbit
The launching appeared to go off without a hitch, but a problem prevented the rocket's upper stage from putting its payload into the correct orbit.
Artemis II crew on historic moon mission and what it means for Earth
"We are carrying back everything we learned, not only about where we went but ourselves," mission specialist Christina Koch told "CBS Evening News" anchor Tony Dokoupil.
Artemis II astronauts still awed by moonshot experience: "It was otherworldly"
The four Artemis II astronauts struggled to describe the view and overall experience of flying around the moon's far side and witnessing a solar eclipse in deep space.
Latest Galleries
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Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
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Latest CBS News Videos
Highlights from Pete Hegseth's testimony
Defense Secretary Pete Hegseth and other top officials testified on Wednesday as the Defense Department seeks a $1.5 trillion budget from Congress. Hegseth got into heated exchanges with Democrats on the House Armed Services Committee and claimed those who oppose the war in Iran are enemies. Acting Pentagon comptroller Jules Hurst also revealed that the conflict has cost the U.S. about $25 billion.
New details on D.C. press dinner shooting
The Justice Department released a photo allegedly showing the suspect in the White House Correspondents' Dinner shooting, roughly 30 minutes before he rushed past security at the event. CBS News' Sam Vinograd has more.
Breaking down Louisiana voting rights case
The Supreme Court handed down a ruling on Wednesday, weakening the Voting Rights Act. The case was about a Louisiana congressional map that added a second majority-Black district to the state. In a three-to-six decision, the court said the new map constituted racial gerrymandering. CBS News' Jessica Levinson and David Becker break down the ruling and Rep. Troy Carter of Louisiana shares his reaction.
Prosecutors allege D4vd killed teen to silence her
Prosecutors on Wednesday alleged singer D4vd killed Celeste Rivas Hernandez to silence her "before she ruined his music career." CBS News Los Angeles reporter Hunter Sowards has the latest.
Coast Guard commandant on power outages
Coast Guard Commandant Adm. Kevin Lunday told CBS News' Nicole Sganga that several Coast Guard stations across the country recently lost power, water or gas. Service has been restored, but he warns more outages could happen as the DHS shutdown continues.