FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
Border czar announces Minnesota immigration operation surge is ending
Border czar Tom Homan announced Thursday the surge of federal immigration officers in Minnesota is concluding, with a drawdown set to occur over the course of next week.
Black gloves found in Nancy Guthrie search, sources say
The gloves will be tested for DNA as the search for Nancy Guthrie continues.
Trump officials oust Abigail Slater as DOJ's antitrust chief, sources say
Top Trump administration officials had decided to terminate Abigail Slater as the Justice Department's anti-trust chief just before she announced her departure on social media.
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Watch Live: ICE chief, immigration officials testify at Senate hearing
The leaders of three major immigration agencies are testifying before the Senate Homeland Security Committee on Thursday.
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Voluntary departures hit record high as detained immigrants lose hope
Vilma Palacios is one of thousands who have given up their immigration cases and voluntarily left the U.S. after being detained. More detainees are opting for voluntary departure than ever before, a CBS News analysis found.
Savannah Guthrie shares video clips of missing mom when she was younger
Savannah Guthrie shared two video clips and a family photo of her mother Nancy Guthrie as the search for the 84-year-old continued.
Civil rights attorneys predict charges against Don Lemon, others will be dismissed
Inexperienced prosecutors are testing FACE Act in their case against Don Lemon. But the law has constitutional problems that make it untenable to charge misconduct in a house of worship.
Judge orders Trump admin. to facilitate return of some deported Venezuelans
A federal judge ordered the Trump administration to facilitate the return of Venezuelan migrants who were deported to a Salvadoran prison last year and then released into other countries.
Rocket has booster problem while launching classified Space Force payloads
A United Launch Alliance Vulcan rocket carrying classified Space Force payloads suffered a booster problem but apparently made an otherwise "nominal" ascent to space, the company said.
U.S.
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Oklahoma executes man for 2006 killings: "I apologize for murdering your sons"
Oklahoma has carried out its first execution of the year on a man convicted of killing two men in a drive-by shooting.
Judge orders Trump admin. to facilitate return of some deported Venezuelans
A federal judge ordered the Trump administration to facilitate the return of Venezuelan migrants who were deported to a Salvadoran prison last year and then released into other countries.
Savannah Guthrie shares video clips of missing mom when she was younger
Savannah Guthrie shared two video clips and a family photo of her mother Nancy Guthrie as the search for the 84-year-old continued.
Southwest's new boarding process off to bumpy start
Some travelers are finding they don't have storage above their seats when they get on the plane because early boarders are taking up the overhead bins.
Trump officials oust Abigail Slater as DOJ's antitrust chief, sources say
Top Trump administration officials had decided to terminate Abigail Slater as the Justice Department's antitrust chief just before she announced her departure on social media.
MoneyWatch
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Southwest's new boarding process off to bumpy start
Some travelers are finding they don't have storage above their seats when they get on the plane because early boarders are taking up the overhead bins.
Trump officials oust Abigail Slater as DOJ's antitrust chief, sources say
Top Trump administration officials had decided to terminate Abigail Slater as the Justice Department's antitrust chief just before she announced her departure on social media.
Some job-seekers are paying thousands of dollars just to land an interview
"Reverse recruitment" firms promise to cut the length of job searches in half and help connect candidates with employers.
Stellantis issues "do not drive" warning for cars with unrepaired air bags
Stellantis is telling owners of the affected vehicles not to drive them until a potentially dangerous air bag is replaced. See which models are affected.
Dispute over Cardi B's Super Bowl cameo roils prediction markets
Cardi B appeared during Bad Bunny's halftime show at the Super Bowl, but one prediction market says it's unclear whether she sang.
Politics
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Judge orders Trump admin. to facilitate return of some deported Venezuelans
A federal judge ordered the Trump administration to facilitate the return of Venezuelan migrants who were deported to a Salvadoran prison last year and then released into other countries.
Trump officials oust Abigail Slater as DOJ's antitrust chief, sources say
Top Trump administration officials had decided to terminate Abigail Slater as the Justice Department's antitrust chief just before she announced her departure on social media.
Civil rights attorneys predict charges against Don Lemon, others will be dismissed
Inexperienced prosecutors are testing FACE Act in their case against Don Lemon. But the law has constitutional problems that make it untenable to charge misconduct in a house of worship.
Exclusive
Warren, Coons introduce bill to strengthen oversight of ICE and CBP
Amid negotiations with the White House, the pair of Democrats is pitching the bill as an enforcement mechanism to go alongside the changes they're seeking.
NATO allies shrug off Hegseth no-show, adjust to slimmed-down U.S. role
America's NATO allies say they're not disappointed by top Trump administration officials skipping summits, as they ramp up their own regional defenses.
HealthWatch
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Moderna says FDA refuses its application for new mRNA flu vaccine
The Food and Drug Administration is refusing to consider Moderna's application for a new flu vaccine made with mRNA technology, the company said.
What to know about a new study on coffee, tea and dementia risk
CBS News medical contributor Dr. Céline Gounder said the results of the study on coffee drinkers having lower risk of dementia should be taken "with a massive grain of salt."
Thousands of mothers were flagged to police over flawed drug tests at childbirth
The Marshall Project found more than 70,000 cases referred to law enforcement over allegations of substance use during pregnancy — and that's a significant undercount.
Obamacare sign-ups drop, but the extent won't be clear for months
Experts say Affordable Care Act sign-up data won't be clear until people who were enrolled have paid — or not — their new, often much higher, premiums.
Hospital flooded by Hurricane Helene to be rebuilt in another flood plain
Ballad Health, the nation's largest state-sanctioned hospital monopoly, plans to rebuild Unicoi County Hospital in Tennessee on land that two climate modeling companies say is at risk of flooding.
World
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Iran blackmails jailed protesters' families, offering leniency for loyalty
Iranian authorities have presented the families of jailed protesters "an inhumane dilemma," offering reprieve in exchange for public acquiescence.
Russia blocks WhatsApp as it pushes state-backed alternative on citizens
The messaging platform WhatsApp says Russia has "attempted to fully block" its service inside the country, "to drive people to a state-owned surveillance app."
NATO allies shrug off Hegseth no-show, adjust to slimmed-down U.S. role
America's NATO allies say they're not disappointed by top Trump administration officials skipping summits, as they ramp up their own regional defenses.
Breezy Johnson crashes out of women's Super-G race, but ends up engaged
Team USA star skier Breezy Johnson was thrown off course during the Super-G event in Italy, but she arrived at the bottom of the slope to a wedding proposal.
Border czar announces Minnesota immigration operation surge is ending
Border czar Tom Homan announced Thursday that Operation Metro Surge in Minnesota is concluding, with a drawdown of federal immigration officers set to occur over the course of next week.
Entertainment
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Entertainment
Constance Zimmer on "The Lincoln Lawyer"
Constance Zimmer, who stars in the new season of "The Lincoln Lawyer," talks about how she channels her powerful character in the series and why it's important for her to always make her characters relatable.
James Van Der Beek dies after cancer battle
James Van Der Beek, known for starring in "Dawson's Creek" and "Varsity Blues," died Wednesday at the age of 48 after a battle with colorectal cancer. Vladimir Duthiers reports on the beloved actor's career.
"Dawson's Creek" co-stars remember James Van Der Beek: "One in a billion"
Katie Holmes and Busy Philipps are among the "Dawson's Creek" cast members sharing memories of James Van Der Beek after his death at age 48.
James Van Der Beek of "Dawson's Creek" dies at 48
James Van Der Beek, star of "Dawson's Creek" and "Varsity Blues," has died at age 48, according to his publicist and a post from his wife on social media. Carter Evans has more on his life and career.
Looking back at James Van Der Beek's life
James Van Der Beek, the star of teen classics like "Varsity Blues" and "Dawson's Creek," has died at the age of 48. His wife posted about his death on Instagram on Wednesday. CBS News correspondent Carter Evans reports.
Technology
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Russia blocks WhatsApp as it pushes state-backed alternative on citizens
The messaging platform WhatsApp says Russia has "attempted to fully block" its service inside the country, "to drive people to a state-owned surveillance app."
How did investigators recover Nancy Guthrie's doorbell footage?
Many are questioning how Nancy Guthrie's Google Nest surveillance footage was recovered days after officials said it was disconnected with no active subscription to store video.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
TikTok to launch local feed that taps users' geolocation data
The social media platform changed its privacy policy last month, inviting users to allow it to track their specific location.
Americans turn to AI for mental health advice
Millions of Americans are turning to AI for emotional therapy. A report in JAMA found about 13% of young people use AI chatbots for mental health advice. Dr. Sue Varma, a board-certified psychiatrist, explains what to know about safety, privacy and ethical standard concerns.
Science
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Scientists "quite surprised" to find one polar bear population thriving
After decades monitoring polar bears in Norway's far north, researchers say the animals have proven incredibly adaptable, but there are no guarantees for the future.
Mysterious dark matter seen in new map of distant galaxies
Dark matter doesn't absorb or give off light so scientists can't study it directly. But they can observe how its gravity warps and bends the star stuff around it.
Cow develops technique to scratch herself
"CBS Saturday Morning" learns more about Veronika, the clever cow who figured out multiple ways to scratch herself with a broom. It was the first time a cow was seen using a tool.
Almanac: January 18
"Sunday Morning" looks back at historical events on this date.
Fossils found at Dinosaur National Monument, first excavation in 100 years
The Dinosaur National Monument, which is located on the border between Colorado and Utah, was last excavated in 1924.
Crime
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Crime
Lawmakers blast Pam Bondi on Epstein files
Abuse survivors were present during a fiery House Judiciary Committee hearing where lawmakers grilled Attorney General Pam Bondi about the latest batch of files released on the investigation into convicted sex offender Jeffrey Epstein. CBS News' Scott MacFarlane reports.
Black gloves found in Nancy Guthrie search
a pair of black gloves were found about a mile away from Nancy Guthrie's home, sources tell CBS News. Jonathan Vigliotti has the latest.
Black gloves found in Nancy Guthrie search, sources say
The gloves will be tested for DNA as the search for Nancy Guthrie continues.
Anger at Pam Bondi hearing over Epstein files
Attorney General Pam Bondi clashed with some lawmakers at her House Judiciary Committee hearing over the Epstein files and their release. CBS News' Taurean Small reports.
More potential evidence in Nancy Guthrie case
Investigators have discovered a pair of black gloves more than a mile from Nancy Guthrie's home, a source close to the investigation tells CBS News. Bradley Blackburn reports and law enforcement contributor Rodney Harrison breaks down more on the investigation.
Space
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ULA rocket has booster problem while launching classified Space Force payloads
A United Launch Alliance Vulcan rocket carrying classified Space Force payloads suffered a booster problem but apparently made an otherwise "nominal" ascent to space, the company said.
New space station crew eager for Wednesday launch
The new crew will replace four station fliers who returned to Earth ahead of schedule last month due to a medical issue.
What led NASA to delay Artemis II launch
NASA's first crewed moon mission in more than 50 years has been delayed until March at the earliest. During a routine dress rehearsal of the launch, persistent liquid hydrogen leaks were discovered in the Artemis II rocket. CBS News space consultant Bill Harwood breaks it down.
NASA hopes to fix Artemis II moon rocket leak with on-pad repair
NASA plans to test the planned leak repair with a second dress rehearsal fueling test later this month.
NASA delays Artemis II launch
NASA delayed the Artemis II moon rocket launch after a hydrogen leak was found during a wet dress rehearsal, the agency announced Tuesday. CBS News senior space consultant Bill Harwood has the latest.
Latest Galleries
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Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
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Latest news on Minnesota ICE operations
Border czar Tom Homan announced changes to the federal immigration operations in Minnesota. CBS News' Camilo Montoya-Galvez and Caitlin Huey-Burns report.
"Love Story" stars on portraying Kennedys
Paul Anthony Kelly and Sarah Pidgeon talk about starring in the limited series "Love Story." It follows the romance of John F. Kennedy Jr. and his wife Carolyn Bessette Kennedy, who died in a 1999 small plane crash along with Bessette Kennedy's sister. The actors talk about how they prepared to portray the iconic couple's lives, challenges they faced and if they spoke to the Kennedy family about it.
Trump could still veto Canada tariffs move
A resolution to curb President Trump's tariffs on Canada may not move past the Senate or President Trump's desk. CBS News' Ed O'Keefe reports.
Homan says Minnesota ICE operation is ending
Tom Homan, President Trump's border czar, announced a change in the federal immigration operations in Minnesota. CBS News' Camilo Montoya-Galvez reports.
U.S. takes silver at ice dance in Olympics
Madison Chock and Evan Bates won the silver medal at the 2026 Winter Olympics ice dance competition after a controversial call led to France winning gold. CBS News' Kelly O'Grady explains.