FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
Nancy Guthrie "still out there," sheriff says, as FBI offers $50,000 reward
Investigators believe the missing mother of "Today" show host Savannah Guthrie is "still out there," but they have not identified any suspects, the sheriff said.
Who entered Epstein's jail tier the night of his death? Files raise new questions.
Newly released documents from the Epstein files raise more questions about activity seen on video from the jail the night he died.
"Tsunami" of immigration cases strains U.S. Attorney's offices across America
As immigration sweeps expand nationwide, the work of justifying detentions is overwhelming federal prosecutors, who are being forced to sideline a range of other cases in order to keep pace.
Exclusive
Maryland man faces attempted murder charges for targeting OMB director
Colin Demarco was arrested in January, months after he was seen in a Ring camera image at Vought's door, wearing a surgical mask and gloves.
A timeline of Nancy Guthrie's disappearance as search intensifies
The search for Savannah's Guthrie's mom, Nancy Guthrie, stretches into a fifth day after she disappeared over the weekend.
Minnesota activist arrested and charged with threatening ICE agents
Prosecutors allege that Kyle Wagner, 37, shared social media posts threatening ICE agents.
What Savannah Guthrie video reveals about strategy to get mom home
In a video message, Savannah Guthrie and her siblings sought to tell their mother's possible abductor – or abductors – that they are "ready to talk."
Spokesperson says both Trump and Bondi asked Gabbard to be at FBI search
President Trump told NBC News he didn't know why Director of National Intelligence Tulsi Gabbard was at the search of the Georgia county's elections office.
Massive release of Epstein files includes 3 million documents and photos
The Justice Department released more new documents Friday from the Jeffrey Epstein files, more than a month after the DOJ's original deadline to do so.
U.S.
More U.S.
Weeks after ice storm in northeast Mississippi, 25,000 still without power
Nearly two weeks after a catastrophic ice storm rocked northeast Mississippi, still 25,000 customers are without power as of Feb. 5.
Frustrations from judge, prosecutor in Minnesota boil over amid Trump's ICE surge
U.S. District Judge Jerry Blackwell admonished the Trump administration for what he said was a failure to comply with judicial orders, warning it is "not above the law."
The typical American worker has $955 saved for retirement
Millions of Americans lack access to any type of retirement plan, hampering their ability to save for old age.
Bad Bunny says 2026 Super Bowl halftime show will "be a huge party"
Bad Bunny says he wants to bring his culture to his Super Bowl halftime show Sunday.
Exclusive
Maryland man faces attempted murder charges for targeting OMB director
Colin Demarco was arrested in January, months after he was seen in a Ring camera image at Vought's door, wearing a surgical mask and gloves.
MoneyWatch
More MoneyWatch
Poll: Fewer feel prices rising, but most see a gap between richest, middle class
Poll on the economy and opportunity finds fewer feel prices rising, while most see a gap between the richest and the middle class.
The typical American worker has $955 saved for retirement
Millions of Americans lack access to any type of retirement plan, hampering their ability to save for old age.
As silver prices soar, jeweler Pandora turns to platinum
One jewelry company is looking to offset surging silver prices by plating its pieces with an even more precious metal.
Layoffs jumped in January as companies pull back on hiring
Employers cut more than 108,000 jobs in January, the highest total for that month since 2009, new data shows.
Why now is a good time to start house-hunting
Housing affordability is improving as more homeowners list their properties, according to data from Zillow.
Politics
More Politics
Frustrations from judge, prosecutor in Minnesota boil over amid Trump's ICE surge
U.S. District Judge Jerry Blackwell admonished the Trump administration for what he said was a failure to comply with judicial orders, warning it is "not above the law."
Poll: Fewer feel prices rising, but most see a gap between richest, middle class
Poll on the economy and opportunity finds fewer feel prices rising, while most see a gap between the richest and the middle class.
"Tsunami" of immigration cases strains U.S. Attorney's offices across America
As immigration sweeps expand nationwide, the work of justifying detentions is overwhelming federal prosecutors, who are being forced to sideline a range of other cases in order to keep pace.
Exclusive
Maryland man faces attempted murder charges for targeting OMB director
Colin Demarco was arrested in January, months after he was seen in a Ring camera image at Vought's door, wearing a surgical mask and gloves.
Who entered Epstein's jail tier the night of his death? Files raise new questions.
Newly released documents from the Epstein files raise more questions about activity seen on video from the jail the night he died.
HealthWatch
More HealthWatch
Officials warn against drinking raw milk after baby dies from listeria
The New Mexico Department of Health said officials believe the baby contracted listeria after their mother drank raw milk during pregnancy.
5 ways to find affordable care without health insurance
Many Americans are expected to lose ACA or Medicaid coverage in the coming months and years, but doctors and researchers say there are still ways to find affordable care.
When health insurance costs more than the mortgage
As health care costs skyrocket and federal lawmakers pull back help on ACA insurance premiums, more middle-income families are facing tough choices on health care.
Extended Interview: Mel Robbins
In this web exclusive, author and podcaster Mel Robbins talks with Norah O'Donnell about "The Let Them Theory."
Book excerpt: "The Let Them Theory" by Mel Robbins
In her latest bestseller, the motivational speaker discusses how personal growth is only possible when you stop pouring energy into things you cannot control – which includes changing other people.
World
More World
Anti-doping agency responds to penis injection claims at Olympics
In ski jumping, a small difference in suit size can make a significant difference in an athlete's performance.
U.S. and Russia agree to resume military-to-military communication
The U.S. on Thursday announced the resumption of dialogue with Russia's military, which had been suspended since 2021.
Concern over safety and justice as U.S. moves 7,000 ISIS suspects to Iraq
Iraq says it's ready to put thousands of ISIS suspects transferred by the U.S. from Syria on trial. Can it really offer "fair and decisive" justice?
Russia says huge meteorite chunk discovered before being smuggled to U.K.
Russia's customs service says a 2.8-ton chunk of the Aletai meteorite was found in a shipping container, labeled as a garden ornament.
Ukraine and Russia carry out first prisoner exchange in 5 months
U.S. envoy Steve Witkoff calls Ukraine and Russia's exchange of 314 prisoners "tangible progress," but acknowledges a lot of work left to end the war.
Entertainment
More Entertainment
Bad Bunny says 2026 Super Bowl halftime show will "be a huge party"
Bad Bunny says he wants to bring his culture to his Super Bowl halftime show Sunday.
LaMonte McLemore, singer and founding member of The 5th Dimension, dies at 90
The 5th Dimension had broad crossover success and won six Grammy Awards, including record of the year twice.
Ron Funches opens up about autism diagnosis
Actor and comedian Ron Funches talks to "CBS Mornings" about appearing on the reality show "The Traitors," how it led to his autism diagnosis and opening up to others about it.
2026 Super Bowl ads to look out for
Super Bowl advertisements are already making waves as companies seek a big win during the NFL's final football game of the season. Jeanine Poggi, the editor-in-chief at Ad Age, joins CBS News with more.
Susan Lucci on life after soap opera stardome
For decades, Susan Lucci starred in "All My Children." She speaks to "CBS Mornings" about her second memoir, which dives into her life after the soap opera series, the death of her husband and the resilience she found along the way.
Technology
More Technology
Technology
How will AI transform the workforce?
CBS News business analyst Jill Schlesinger talks about how companies are using artificial intelligence, the discussion around the technology and how it's impacting the workforce.
Tesla, Waymo leaders defend product safety
Executives from Waymo and Tesla defended their self-driving vehicle technology in testimony before the Senate Commerce Committee on Wednesday. CBS News' Kris Van Cleave reports and Ian Krietzberg, an AI correspondent at the digital media company Puck, has more.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
iPhone flip to reportedly launch
Apple is reportedly getting ready to launch its first foldable phone. Plus, OpenAI announced it is retiring its older ChatGPT-4o. Mashable tech editor Tim Werth joins CBS News to discuss.
Tesla, Waymo execs defend self-driving cars before Senate committee
"Right now we have the Wild West. I want to see some rules of the road," said Democratic Sen. Richard Blumenthal.
Science
More Science
Scientists "quite surprised" to find one polar bear population thriving
After decades monitoring polar bears in Norway's far north, researchers say the animals have proven incredibly adaptable, but there are no guarantees for the future.
Mysterious dark matter seen in new map of distant galaxies
Dark matter doesn't absorb or give off light so scientists can't study it directly. But they can observe how its gravity warps and bends the star stuff around it.
Cow develops technique to scratch herself
"CBS Saturday Morning" learns more about Veronika, the clever cow who figured out multiple ways to scratch herself with a broom. It was the first time a cow was seen using a tool.
Almanac: January 18
"Sunday Morning" looks back at historical events on this date.
Fossils found at Dinosaur National Monument, first excavation in 100 years
The Dinosaur National Monument, which is located on the border between Colorado and Utah, was last excavated in 1924.
Crime
More Crime
Crime
Officials: Nancy Guthrie is "still out there"
Investigators believe "Today" show co-host Savannah Guthrie's mother, Nancy, is "still out there." CBS News' Andres Gutierrez and Anna Schecter have the latest on the search for the missing woman.
FBI: Deadline on Guthrie ransom note is 5 p.m.
The FBI has announced a $50,000 reward for information in the disappearance of Nancy Guthrie, the mother of "Today" show host Savannah Guthrie. CBS News' Anna Schecter breaks down what we know and Marlon Marrache, a retired LAPD sergeant, joins with analysis.
Latest details on Nancy Guthrie disappearance
Officials gave an update Thursday on the disappearance of Nancy Guthrie, saying they believe she is "still out there" and offering a $50,000 reward for information in the case. CBS News' Andres Gutierrez and Anna Schecter have more.
$50,000 reward offered for Nancy Guthrie info
The FBI said it's offering a $50,000 reward for information leading to Savannah Guthrie's mother, Nancy, as the search continues for the 84-year-old who was last seen at her Arizona home on Saturday. Pima County Sheriff Chris Nanos said he believes Nancy Guthrie is "still out there."
Nancy Guthrie "still out there," sheriff says, as FBI offers $50,000 reward
Investigators have no proof that the missing mother of "Today" show host Savannah Guthrie is still alive but are holding out hope she is "still out there," the sheriff said.
Space
More Space
Space
What led NASA to delay Artemis II launch
NASA's first crewed moon mission in more than 50 years has been delayed until March at the earliest. During a routine dress rehearsal of the launch, persistent liquid hydrogen leaks were discovered in the Artemis II rocket. CBS News space consultant Bill Harwood breaks it down.
NASA hopes to fix Artemis II moon rocket leak with on-pad repair
NASA plans to test the planned leak repair with a second dress rehearsal fueling test later this month.
NASA delays Artemis II launch
NASA delayed the Artemis II moon rocket launch after a hydrogen leak was found during a wet dress rehearsal, the agency announced Tuesday. CBS News senior space consultant Bill Harwood has the latest.
NASA begins mission to map the boundaries of our heliosphere
A NASA mission is underway to map the heliosphere, which is a huge protective bubble around the solar system that was created by the sun.
NASA moon launch off until March due to issues during tests
NASA says it can't try until March at the earliest to send a crewed spacecraft on a flight around the moon and back, due to hydrogen leaks during testing of the Artemis II rocket.
Latest Galleries
More Latest Galleries
Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
More Latest CBS News Videos
Latest CBS News Videos
Arthur Brooks on misconceptions about therapy
A growing number of Americans are seeking time with a counselor to help treat depression and anxiety. One in seven Americans received mental health counseling or therapy in 2024, according to the CDC. However, CBS News contributor Arthur Brooks says therapy won't necessarily make you happier. He joins "CBS Mornings News" to talk about how to improve your well-being and his upcoming book, "The Meaning of Your Life: Finding Purpose in an Age of Emptiness."
Concerns about health care costs
According to a new KFF Health tracking poll, two-thirds of those surveyed say they worry about not being able to afford health coverage and more than half say costs have gone up in the past year. Renuka Rayasam, senior correspondent at KFF Health News, joins CBS News to discuss.
U.S.-Russia nuclear treaty expires
The U.S. and Russia have agreed to hold high-level military talks just hours after the last remaining nuclear treaty between the two super-powers expired. CBS News White House reporter Willie James Inman has more.
Sheriff, FBI on Nancy Guthrie search
Pima County Sheriff Chris Nanos and Heith Janke, the special agent in charge of the FBI's field office in Phoenix, gave an update on the investigation into Nancy Guthrie's disappearance. Nanos said investigators believe Guthrie is "still out there." The FBI is offering a $50,000 reward for information on her whereabouts.
Officials: Nancy Guthrie is "still out there"
Investigators believe "Today" show co-host Savannah Guthrie's mother, Nancy, is "still out there." CBS News' Andres Gutierrez and Anna Schecter have the latest on the search for the missing woman.