FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
Live
Hegseth says U.S. "just getting started" as Iran war spreads
The U.S. is "accelerating, not decelerating" war on Iran, Hegseth says, as strikes intensify in the region and reach 1,000 miles away.
Senate rejects attempt to rein in Trump's power to wage war on Iran
The measure, which would have blocked President Trump from continuing military force against Iran, fell short of the simple majority needed to advance.
Key takeaways from House hearing with Walz, Ellison on Minnesota fraud
Minnesota Gov. Tim Walz told lawmakers that fraud "happened on my watch," but defended his administration's handling of the allegations.
U.S. torpedo sinks Iranian warship, Hegseth says
In Defense Secretary Pete Hegseth's second news briefing since the start of the Iran war, Hegseth said the U.S. had sunk an enemy ship by a torpedo for the first time since World War II.
Probe into Biden autopen closed by D.C. U.S. Attorney's Office, source says
Federal prosecutors are dropping their probe into whether Biden and his aides unlawfully used an autopen for pardons, a source said.
Companies are entitled to Trump tariff refunds, trade court rules
A federal court in New York ruled Wednesday that businesses that paid emergency tariffs invalidated by the Supreme Court are eligible for refunds.
GOP senator joins police in ejecting protester from Capitol Hill hearing
A Senate Republican assisted several police officers in ejecting a man who interrupted a Capitol Hill hearing on Wednesday to object to the U.S. and Israel's war with Iran.
Rep. Tony Gonzales admits to affair with former staffer, calling it a "mistake"
Republican Rep. Tony Gonzales of Texas acknowledged for the first time Wednesday that he had a relationship with a former staffer, but alleged the controversy that has engulfed the situation is "about power and money."
Exclusive
Anthropic CEO: We're trying to "deescalate" Pentagon AI standoff to reach agreement
Anthropic CEO Dario Amodei said his company and the Department of Defense "have much more in common than we have differences."
U.S.
More U.S.
Rep. Tony Gonzales admits to affair with former staffer, calling it a "mistake"
Republican Rep. Tony Gonzales of Texas acknowledged for the first time Wednesday that he had a relationship with a former staffer, but alleged the controversy that has engulfed the situation is "about power and money."
GOP Sen. Steve Daines of Montana won't seek reelection
Sen. Steve Daines said he had wrestled with the decision for months.
Israel's president: It's "time that everybody tells Iran, 'Guys, we're fed up'"
In an interview with CBS News Wednesday, Israeli President Isaac Herzog said that he is "not calling on any boots on the ground" in Iran.
Man arrested in Virginia is latest Jan. 6 defendant to face new charges
Jonathan Munafo is among the Jan. 6 riot defendants who have been arrested on charges in new cases in the months after their pardons.
Elon Musk testifies in Twitter shareholder trial over actions before purchase
Elon Musk reached a deal to buy Twitter in April 2022. On May 13, 2022, he declared his plan "temporarily on hold" over the number of spam and fake accounts on the platform. Twitter's stock tumbled as a result.
MoneyWatch
More MoneyWatch
Elon Musk testifies in Twitter shareholder trial over actions before purchase
Elon Musk reached a deal to buy Twitter in April 2022. On May 13, 2022, he declared his plan "temporarily on hold" over the number of spam and fake accounts on the platform. Twitter's stock tumbled as a result.
Companies are entitled to Trump tariff refunds, trade court rules
A federal court in New York ruled Wednesday that businesses that paid emergency tariffs invalidated by the Supreme Court are eligible for refunds.
Nearly 37 million pounds of food recalled because it could contain glass
Oregon food manufacturer Ajinomoto expands an earlier recall of frozen and ready-to-eat products over glass contamination.
Google faces first lawsuit alleging its AI chatbot encouraged man's suicide
Google is accused in a wrongful death lawsuit filed by the family of a man who committed suicide in October, allegedly at the direction of the tech giant's AI chatbot, Gemini.
Tariff refund delays could cost U.S. $700 million a month in interest
The U.S. government must also reimburse businesses for the interest they paid on tariffs recently struck down by the Supreme Court, according to the Cato Institute.
Politics
More Politics
Rep. Tony Gonzales admits to affair with former staffer, calling it a "mistake"
Republican Rep. Tony Gonzales of Texas acknowledged for the first time Wednesday that he had a relationship with a former staffer, but alleged the controversy that has engulfed the situation is "about power and money."
GOP Sen. Steve Daines of Montana won't seek reelection
Sen. Steve Daines said he had wrestled with the decision for months.
Israel's president: It's "time that everybody tells Iran, 'Guys, we're fed up'"
In an interview with CBS News Wednesday, Israeli President Isaac Herzog said that he is "not calling on any boots on the ground" in Iran.
GOP senator joins police in ejecting protester from Capitol Hill hearing
A Senate Republican assisted several police officers in ejecting a man who interrupted a Capitol Hill hearing on Wednesday to object to the U.S. and Israel's war with Iran.
Man arrested in Virginia is latest Jan. 6 defendant to face new charges
Jonathan Munafo is among the Jan. 6 riot defendants who have been arrested on charges in new cases in the months after their pardons.
HealthWatch
More HealthWatch
Some baby formula brands contain heavy metals, Consumer Reports says
Tests of dozens of baby formulas by Consumer Reports found that nearly half contained potentially dangerous chemicals.
States face pushback on their rural health transformation plans
Some Republican state lawmakers and health associations are pushing back against spending plans under the Trump administration's $50 billion federal rural health fund.
Chocolate supplement recalled over erectile dysfunction drug
USALESS.COM is recalling its Rhino Choco VIP 10X product due to the undeclared presence of Tadalafil, which is the active ingredient in Cialis.
College student's mystery illness diagnosed as Stage IV cancer
Emma Operacz was diagnosed with a rare cancer at 21. An unusual treatment and bone marrow donation from her sister saved her life.
Medicaid is paying for more dental care. GOP cuts threaten to reverse the trend.
More than three dozen states cover dental services for people on Medicaid, but with about $900 billion in cuts expected to hit states over the next decade, many programs could roll back dental coverage.
World
More World
Israel's president: It's "time that everybody tells Iran, 'Guys, we're fed up'"
In an interview with CBS News Wednesday, Israeli President Isaac Herzog said that he is "not calling on any boots on the ground" in Iran.
What we know about U.S. service members killed in Iran war
The fallen soldiers identified by the Pentagon were Sgt. Declan Coady, Sgt. 1st Class Nicole Amor, Capt. Cody Khork, Sgt. 1st Class Noah Tietjens and Maj. Jeffrey R. O'Brien.
Iran says a girls' school was hit by a deadly air strike. Here's what we know.
Iranian officials say more than 170 people were killed in the strike. Neither the U.S. nor Israel has said it was behind the attack, but the Pentagon is investigating.
Cuba charges 6 suspects with terrorism over fatal U.S. boat shooting
The government unveiled items said to have been found on the boat, including high-powered weapons, more than 12,800 pieces of ammunition and 11 pistols.
Hegseth says U.S. torpedo sank an Iranian warship as military campaign ramps up
In Defense Secretary Pete Hegseth's second news briefing since the start of the Iran war, Hegseth said the U.S. had sunk an enemy ship by a torpedo for the first time since World War II.
Entertainment
More Entertainment
Entertainment
True crime series spotlights U.S. small towns
Hilarie Burton Morgan, known for playing Peyton on "One Tree Hill," talks about her docuseries, "True Crime Story: It Couldn't Happen Here," which is in its third season. She explains how each episode highlights a case in a small town in the U.S., how the series empowers the audience and recent developments in a cold case.
Padma Lakshmi talks "America's Culinary Cup"
TV host and food expert Padma Lakshmi, the creator and executive producer of the new CBS series, "America's Culinary Cup," speaks to "CBS Mornings" about creating the cooking competition and how it's different from other shows.
How families can change their habits
Bestselling author Michaeleen Doucleff offers science-backed tips on how families can curb their screen time and cut back on ultraprocessed foods. She explains how her new book, which is aimed at rewiring children's brains, began with a personal revelation.
Luke Grimes on "Marshals"
Actor Luke Grimes talks about starring in the "Yellowstone" spinoff "Marshals." Grimes reveals why he was hesitant to join the cast at first and what it was like to have his new song "Haunted" to play in the premiere episode.
Preview of UFC 326: Holloway vs. Oliveira
UFC commentator Laura Sanko joins "CBS Mornings" to preview Saturday's UFC fight where defending champion Max Holloway will take on Charles Oliveira for the BMF title.
Technology
More Technology
Exclusive
Anthropic CEO: We're trying to "deescalate" Pentagon AI standoff to reach agreement
Anthropic CEO Dario Amodei said his company and the Department of Defense "have much more in common than we have differences."
OpenAI changing Pentagon deal after backlash
Hours after the Trump administration ditched Anthropic over the dispute about AI use, OpenAI struck its own deal with the Pentagon. Now the details of that agreement appear to be changing after backlash. Katrina Manson, Bloomberg News reporter, has more.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
Amazon says drones hit 3 of its Middle East data centers
Drones struck two facilities in the United Arab Emirates directly, and damaged a data center in Bahrain, Amazon said.
Exclusive
AI executive Dario Amodei on the red lines Anthropic would not cross
The CEO of Anthropic says his company refused to allow its technology to be used by the Trump Administration without certain guidelines (such as not using its AI to power fully-autonomous weapons without any human involvement).
Science
More Science
NASA announces major overhaul of Artemis moon program "to take down risk"
NASA Administrator Jared Isaacman announced significant changes to the agency's Artemis program, which aims to land on the moon in 2028.
What scientists will be looking for when government UFO files are released
Documents might help scientists shed light on unexplained phenomena and government secrets, experts said.
In a first, shark seen on camera in Antarctica waters, surprising researchers
A large shark was caught on camera for the first time in Antarctica's waters, surprising researchers. "There's a general rule of thumb that you don't get sharks in Antarctica," one said.
How Washington's crossing of the Delaware presaged a changing world
On the evening of Christmas 1776, Gen. George Washington surprised the King's forces by leading the Continental Army in a surprise crossing of a near-frozen Delaware River - a watershed military maneuver that dramatized a changing America, and a changing climate.
These United States: George Washington and climate change
On the evening of Christmas 1776, Gen. George Washington surprised the King's forces by leading the Continental Army in an unanticipated crossing of a near-frozen Delaware River. Environmental correspondent David Schechter looks at how Washington's watershed military maneuver dramatized both a changing America, and a changing climate.
Crime
More Crime
Gloves found near Guthrie's home tied to restaurant worker, no connection to case
DNA from the gloves found near Nancy Gunthrie's Arizona home was traced back to a local restaurant worker who has no connection to the investigation, the Pima County Sheriff's Department said.
Exclusive
Justice Dept. employee charged in child pornography case
Timothy Parsons, a legal staffer at the U.S. Attorney's Office in Washington, D.C., is facing federal criminal charges in Maryland, where he lives, three sources said.
Officers who killed Austin gunman "undoubtedly saved lives," DA says
Travis County DA Jose Garza said suggestions that he would seek charges were "intentionally false" and political in nature, calling the officers heroes.
Cuba charges 6 suspects with terrorism over fatal U.S. boat shooting
The government unveiled items said to have been found on the boat, including high-powered weapons, more than 12,800 pieces of ammunition and 11 pistols.
Dad of accused school shooter found guilty
A jury found Colin Gray, the father of an accused Georgia high school shooter, guilty on all 27 counts Tuesday, including second-degree murder. Last week Gray testified in his own defense that he never noticied any signs of trouble with his son, Colt Gray, who is charged with opening fire and killing four people inside Apalachee High School in 2024.
Space
More Space
Space
Why NASA is overhauling Artemis program
NASA has announced a major overhaul of its Artemis moon program amid ongoing safety concerns. CBS News space consultant Bill Harwood has more details.
How NASA plans to get astronauts on the moon
NASA announced an overhaul to its Artemis moon program as safety concerns persist. CBS News space contributor Christian Davenport breaks down the key takeaways.
NASA announces major overhaul of Artemis moon program "to take down risk"
NASA Administrator Jared Isaacman announced significant changes to the agency's Artemis program, which aims to land on the moon in 2028.
Safety concerns over NASA's Artemis program
NASA's Artemis II mission continues to face concerns and delays. Scott E. Parazynski, a former astronaut, joins CBS News with more.
NASA rolls Artemis II back for repairs
NASA is rolling back the Artemis II moon rocket from its launch pad at the Kennedy Space Center in Florida. It is expected to take up to 12 hours to move the 322-foot rocket, with the journey spanning four miles back to its hangar for repairs. CBS News space consultant Bill Harwood has more.
Latest Galleries
More Latest Galleries
Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
More Latest CBS News Videos
Latest CBS News Videos
U.S. torpedos Iranian warship as war expands
An American submarine sunk an Iranian warship with a torpedo — the first such incident since World War II. Meanwhile, Iran is widening its ring of retaliation. Tony Dokoupil has the latest.
Americans stuck in Middle East speak out
As the war in Iran raged on, many American travelers remained trapped in the Middle East. Some spoke out about their travel experience and communications with the State Department.
U.S. consumers already feeling impact of Iran conflict
In just one week, the national average for a gallon of regular gas is up about 22 cents. Kelly O'Grady explains.
Antitrust trial against Ticketmaster underway
A landmark federal antitrust trial against Ticketmaster's parent company, Live Nation, got underway this week with the first witness testifying on Wednesday. Antitrust attorney Kenneth Dintzer was in the courtroom and joins "The Daily Report" to discuss.
CBS News producer George Osterkamp dies at 82
CBS News is remembering producer George Osterkamp, who worked at the network for more than three decades.