FDA declines approval bid for Neffy, a needle-free EpiPen alternative
ASR Pharma said it was surprised and "deeply disappointed" by the FDA request for more trial data on its Neffy nasal spray for severe allergic reactions.
Epipen
FDA rejects approval of epinephrine nasal spray
The Food and Drug Administration on Tuesday declined to approve Neffy, an epinephrine nasal spray that offers a needle-free alternative for treating severe allergic reactions. The FDA said Neffy needs more research.
In-flight emergencies raise concerns about airlines' medical kit requirements
About one out of every 600 flights has an in-flight medical emergency, one report found.
Reported EpiPen failures
Mylan, the drug company that created outrage with the dramatic price hike of the EpiPen, is on the defensive again. A new report shows a big rise in complaints about the device not working in life-threatening emergencies. Tony Dokoupil reports.
EpiPen competition
Prices for the EpiPen have soared more than 480% in the past 7 years. Now, generic brands and versions from other companies gaining market share. CBS News correspondent Anna Werner joins CBSN to discuss confusion over the cost of the emergency allergy treatment.
Prices of EpiPen alternatives
There are now more choices for millions of people who relied on the EpiPen for life-threatening allergies, but there is still confusion over the treatments' costs. The Auvi-Q is an epinephrine auto-injector alternative that's listed as $4,500 for a two-pack. But most patients aren't paying a penny of that, leading to the question: who is? Anna Werner reports.
Latest MoneyWatch headlines
U.S. labor market on fire, latest job numbers suggests; EpiPen makers accused of $1.3B gov't ripoff; and 1 in 4 U.S. malls could close in next decade. These headlines and more from CBS MoneyWatch.
MoneyWatch headlines
U.S. GDP shrank in fourth quarter; Trump administration weighs Mexico tariff; and Mylan CEO understands public concerns about drug costs. These headlines and more from CBS MoneyWatch.
Mylan CEO on EpiPen price hike
Pharmaceutical giant Mylan was at the center of criticism last year over rising drug prices. Its EpiPen became the lightning rod for scrutiny, as the life-saving allergy drug's price increased by nearly 500 percent over seven years. In her first in-depth interview since giving testimony before Congress, Mylan CEO Heather Bresch talks to Norah O'Donnell and responds to the outrage among lawmakers and consumers.
Mylan CEO on competition
Heather Bresch, who was called before Congress last year to explain why EpiPen's price had soared by nearly 500 percent over seven years, tells Norah O'Donnell why a competing product on the market doesn't necessarily bring prices down.
Mylan CEO on EpiPen controversy
Mylan CEO Heather Bresch is opening up about the firestorm created by the nearly-500 percent increase in the price of EpiPens. She was called to testify before Congress last year about the $600 price tag for the life-saving allergy medicine. In an interview with Norah O'Donnell, Bresch told us bigger change is needed to fix what she calls a broken healthcare system. Watch the full interview Friday on "CBS This Morning."
EpiPen price hike hearing
On Capitol Hill, Mylan CEO Heather Bresch strongly defended the EpiPen's nearly-500 percent price hike, testifying under oath. CBS News reviewed documents the company turned over to lawmakers that showed how much Mylan expected the EpiPen to generate in net sales this year. Vinita Nair reports.
Mylan EpiPen prices
Mylan CEO Heather Bresch faced bipartisan backlash for her company's pricing and revenue strategy on Wednesday on Capitol Hill. The price of EpiPens has increased from about $100 for a two pack to more than $600. Vinita Nair reports.
EpiPen price hike
New controversy swirls around the maker of the EpiPen, as the mother of Mylan CEO Heather Bresch reportedly helped the company establish a near-monopoly in schools, as the head of a national education group. CBS News' reporting last month on the nearly-500 percent price hike on the EpiPen prompted widespread public backlash, and Bresch is set to testify today on Capitol Hill about the price increase. Vinita Nair reports.
Generic EpiPen
The maker of EpiPen says it will release a generic version of the live-saving drug that will cost roughly half of the original price. WCBS medical correspondent Dr. Max Gomez joins CBSN to discuss the alternative option.
EpiPen price hike
Mylan CEO Heather Bresch went on the offensive Thursday as the company announced it would provide consumers a discount for the EpiPen. The pharmaceutical company has raised the price of the life-saving device by 500% since 2009. Vinita Nair reports.
Latest MoneyWatch headlines
Mylan to expand discounts for EpiPen drug amid backlash; Obama administration defends Affordable Care Act program; Facebook to target WhatsApp users with ads. These headlines and more from CBS MoneyWatch.
EpiPen maker accused of gouging consumers, and other MoneyWatch headlines
Lawmakers blast Mylan for nearly 500% hike in price of life-saving EpiPen drug; Tesla anoints Model S world's fastest production car; and McDonald's recalls fitness bands. These headlines and more from CBS MoneyWatch.
EpiPen price hike
The maker of EpiPen, a potentially life-saving medical device for severe allergic reactions, is now under Congressional scrutiny over how its cost has risen nearly 500 percent since 2009. But one prominent and controversial figure, former pharma CEO Martin Shkreli who has no connections to the EpiPen product, is defending the increase. Vinita Nair reports.
Martin Shkreli on EpiPen
In a conversation with CBS News' Vinita Nair, controversial former CEO of Turing Pharmaceuticals defends drug-maker Mylan for its skyrocketing cost of the device that delivers a life-saving injection for people with severe allergies. Shkreli has no connection with the EpiPen product. He also claims he is "innocent" of his own, unrelated federal securities fraud charges.
8/23: Evening News
Donald Trump is re-tooling his controversial immigration policy, which included a vow to deport 11 million undocumented immigrants; Mississippi firefighter Patrick Hardison's life changed in 2001 when the roof of a burning house collapsed on him
Shkreli on EpiPen
Several members of Congress are demanding to know why the price of EpiPens has skyrocketed by 500 percent. The devices deliver a life-saving injection for people with severe allergies. Vinita Nair spoke with a former pharmaceutical exec who faced similar criticism last year.
Martin Shkreli interview
The cost of EpiPens are on the rise. Founder and former CEO of Turing Pharmaceuticals, Martin Shkreli, joins CBSN with to discuss why he believes the price hike is justified and why he raised the price of Daraprim by 5000%.
EpiPen price soaring
Families with severe allergies often rely on EpiPens to deliver a dose of potentially life-saving medicine if a child has a bad reaction. But the cost of the EpiPen is surging, having risen by more than 480 percent since 2009, putting the pinch on many families. Vinita Nair reports.
Pfizer buying Mylan to create generic drug giant
Pfizer will split off its Upjohn unit, which makes Lipitor, to create a business with at least $19 billion in sales
DOJ says "over a million more documents" found, potentially related to Epstein case
The Justice Department said the process of releasing the Epstein files may take "a few more weeks" due to the volume of materials.
Powerball $1.817 billion Christmas Eve jackpot won by one ticket, in Arkansas
A single winning ticket was sold for Powerball's Christmas Eve jackpot of $1.817 billion, in Arkansas. It was the second biggest winning jackpot in U.S. lottery history.
We asked experts to rate the U.S. economy in 2025. Here's what they said.
The economy remained on track this year, defying the gloomiest predictions. That doesn't mean Americans are thrilled with how things are going.
Trump suggests pulling licenses if networks are "almost 100% Negative" about him
President Trump said TV broadcast licenses should be revoked if newscasts and late-night shows are almost entirely negative about him and the GOP.
California storm threatens homes and holiday travel
Forecasters said Southern California could see its wettest Christmas in years and warned about flash flooding and mudslides, especially in areas scorched by wildfires.
Kennedy Center Christmas Eve concert canceled after Trump's name added
A planned Christmas Eve jazz concert at the Kennedy Center has been canceled.
DOJ releases huge set of Epstein files with many mentions of Trump
The Justice Department early Tuesday released more than 11,000 additional documents and photos from the Jeffrey Epstein files.
Thousands attend Christmas Eve events in Bethlehem, first since Gaza war
Thousands of people traveled from nearby towns and villages to attend Bethlehem's annual Christmas Eve tree lighting ceremony, which was canceled the last two years.
NORAD tracks Santa in Christmas tradition. See the live map.
NORAD, the North American Aerospace Defense Command, tracks Santa's Christmas Eve flight around the world each year. Follow a live map of the tracker here.
U.S.
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Powerball $1.817 billion Christmas Eve jackpot won by one ticket, in Arkansas
A single winning ticket was sold for Powerball's Christmas Eve jackpot of $1.817 billion, in Arkansas. It was the second-largest U.S. lottery jackpot ever won.
NHTSA investigating Tesla Model 3 emergency door handles
Traffic safety regulators are reviewing a motorist's complaints that the manual door handles on some Model 3 cars are hard to find, a potential hazard in a crash.
Hawaii cruise passengers face new climate change tax after court ruling
The new tourist tax imposes an 11% tax on the gross fares paid by a cruise ship's passengers to address climate change threats to Hawaii.
DOJ says "over a million more documents" found, potentially related to Epstein case
The Justice Department said the process of releasing the Epstein files may take "a few more weeks" due to the volume of materials.
How to save money on your utility bill this winter as heating costs rise
Many Americans face soaring costs to heat their homes this winter. Here are some ways to lower your monthly utility bill.
MoneyWatch
More MoneyWatch
NHTSA investigating Tesla Model 3 emergency door handles
Traffic safety regulators are reviewing a motorist's complaints that the manual door handles on some Model 3 cars are hard to find, a potential hazard in a crash.
Hawaii cruise passengers face new climate change tax after court ruling
The new tourist tax imposes an 11% tax on the gross fares paid by a cruise ship's passengers to address climate change threats to Hawaii.
How to save money on your utility bill this winter as heating costs rise
Many Americans face soaring costs to heat their homes this winter. Here are some ways to lower your monthly utility bill.
We asked experts to rate the U.S. economy in 2025. Here's what they said.
The economy remained on track this year, defying the gloomiest predictions. That doesn't mean Americans are thrilled with how things are going.
U.S. says China's chip policies are unfair but will delay tariffs to 2027
The U.S. Trade Representative said tariffs on Chinese semiconductors, now at zero, are set to increase in June 2027.
Politics
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Kennedy Center Christmas Eve concert canceled after Trump's name added
A planned Christmas Eve jazz concert at the Kennedy Center has been canceled.
Trump promises to guard against "bad Santa" in Christmas Eve calls with kids
President Trump spent part of Christmas Eve bantering with kids, updating families on NORAD's Santa tracker and reminding one child that the big guy has a "serious appetite."
Trump-backed candidate declared winner of Honduras' presidential vote
President Trump-backed candidate Nasry Asfura has won Honduras' presidential election, the country's electoral authorities said, ending a weeks-long count.
DOJ says "over a million more documents" found, potentially related to Epstein case
The Justice Department said the process of releasing the Epstein files may take "a few more weeks" due to the volume of materials.
Judge blocks Trump from stripping security clearance from attorney for now
Trump signed an executive order in March saying it was "no longer in the national interest" for attorney Mark Zaid and others to access classified information.
HealthWatch
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FDA approves Wegovy pill for weight loss
The Food and Drug Administration has approved a pill version of the weight-loss drug Wegovy.
Aetna to cover IVF treatments for same-sex couples in national settlement
A federal judge has approved a preliminary agreement for a class action lawsuit requiring Aetna to cover fertility treatments for same-sex couples as they do with heterosexual couples.
Flu season is ramping up, and some experts are "pretty worried"
Doctors and scientists say this year's influenza season could be tougher than usual, with a new version of the flu virus, called H3N2, spreading quickly.
Finding hope through cancer clinical trials
#LillyPartner Cancer clinical trials can offer patients access to investigational treatments that can be explored as early as the time of diagnosis. Ovarian cancer survivor Alicia Dellario and Dr. Arjun Balar, senior vice president of global clinical development at Eli Lilly and Company, join "CBS Mornings" to talk about the potential benefits of cancer clinical trials -- and clarify common misconceptions. Visit cancerclinicaltrials.lilly.com for more information. (Sponsored by Eli Lilly and Company)
Details on new flu strain as cases rise
The Centers for Disease Control and Prevention estimates there have been 4.6 million flu cases across the U.S. since the season began. Dr. Amanda Kravitz, a pediatrician at Weill Cornell in New York, explains what to know about rising cases, symptoms to watch for and how to protect your family.
World
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Trump-backed candidate declared winner of Honduras' presidential vote
President Trump-backed candidate Nasry Asfura has won Honduras' presidential election, the country's electoral authorities said, ending a weeks-long count.
Photos of ways Christmas is celebrated all around the world
Billions worldwide mark the birth of Jesus of Nazareth with various traditions.
Investigators probe plane crash in Turkey that killed Libyan military officials
The private jet carrying Libya's Gen. Muhammad Ali Ahmad al-Haddad and four other military officials crashed on Tuesday.
Thousands attend Christmas Eve events in Bethlehem, the first since Gaza war
Thousands of people traveled from nearby towns and villages to attend Bethlehem's annual Christmas Eve tree lighting ceremony, which was canceled the last two years.
Ukraine peace plan might include demilitarized zones, Zelenskyy says
Ukrainian President Volodymyr Zelenskyy says a plan to end his country's war with Russia might include the establishment of demilitarized zones between Ukrianian and Russian forces.
Entertainment
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Kennedy Center Christmas Eve concert canceled after Trump's name added
A planned Christmas Eve jazz concert at the Kennedy Center has been canceled.
NYT movie critic breaks down top 2025 movies
The New York Times movie critic Alissa Wilkinson ranked the top films of 2025. She joins CBS News 24/7 to review this year's list.
Small Oklahoma town pays homage to leg lamp
The leg lamp in "A Christmas Story" might be one of cinema's most iconic props, and one small town in Oklahoma has a special way to celebrate it. Omar Villafranca reports.
Kiefer Sutherland on new comedy "Tinsel Town"
Kiefer Sutherland stars in the new holiday comedy "Tinsel Town," about a washed-up Hollywood actor who lands in a small English town doing a theater production of "Cinderella." He talks about what drew him to the role.
Taylor Swift donates $1 million to Feeding America, group says
Feeding America's CEO said the organization is "incredibly grateful" for Taylor Swift's large donation.
Technology
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Technology
Instacart ending AI price tests for retailers
Instacart says its ending its controversial system of using AI price tests for retailers. Earlier this month, an investigation by Consumer Reports and progressive think tank Groundwork Collaborative found that Instacart's algorithmic pricing charged various prices for the same item from the same store. Jo Ling Kent reports.
Tech companies push for data centers
Massive tech companies wanting to build more data centers in the U.S. are lobbying for support among Americans, according to a recent report by POLITICO. Gabby Miller joins CBS News with more on her reporting.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
Top tech gadgets of 2025
Timothy Werth, a tech editor at Mashable, joins "CBS News 24/7" to discuss the best gadgets of 2025.
Instacart to end AI price tests for retailers following investigation
Instacart had drawn criticism for testing an AI-based system that enabled retailers to charge different prices for the same grocery items.
Science
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Major climate research center on Trump administration chopping block
The Trump administration intends to dismantle one of the world's leading climate research institutions, in Boulder, Colorado, over what it said were concerns about "climate alarmism."
Researchers capture video of rare polar bear adoption
The footage of a bear caring for an adopted cub was captured during the annual polar bear migration along the Western Hudson Bay in Churchill, Manitoba.
Dinosaur tracks showing "herds moving in synchrony" found in Italy
Most of the footprints are elongated and made by bipeds. The best-preserved ones bear traces of at least four toes.
Interstellar comet is making its closest approach to Earth
NASA continues to aim its space telescopes at the visiting ice ball, estimated to be up to 3.5 miles in size.
Fossil footprints in Bolivia reveal dinosaurs' awkward attempts to swim
Paleontologists have discovered and documented 16,600 footprints left by theropods, the dinosaur group that includes the Tyrannosaurus rex.
Crime
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Terry Rozier seeks to have charges thrown out in NBA gambling case
His lawyers argued that Rozier's alleged involvement in the wire fraud and money laundering conspiracies is limited.
California farming magnate arrested in Arizona in wife's shooting death
A prominent California farmer was arrested in the shooting death of his estranged wife in a remote mountain community in Arizona, authorities said.
D.C. National Guard shooting suspect facing 5 additional federal charges
Rahmanullah Lakanwal, a 29-year-old Afghan national, is accused of fatally shooting Army Spc. Sarah Beckstrom and wounding Air Force Staff Sgt. Andrew Wolfe.
Officials: Melodee Buzzard's body recovered
California authorities announced Tuesday they have found the body of 9-year-old Melodee Buzzard and arrested her mother for murder. See the full news conference.
Delaware state trooper killed in DMV shooting
A Delaware state trooper was killed Tuesday during a shooting at a Wilmington DMV, the Delaware State Police said. The state's governor confirmed the shooter is also dead.
Space
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Space
NASA's search for next lunar rover
NASA astronauts took their first drive on the moon 54 years ago. Now, three companies are competing for a NASA contract to build a new lunar rover for use starting with the Artemis 5 mission in 2030. Kris Van Cleave reports.
Artemis 2 astronauts rehearse countdown for upcoming moon launch
NASA is gearing up to send four Artemis astronauts on looping test flight around the moon in 2026.
Woman is first wheelchair user launched into space
A German aerospace engineer made history Saturday, becoming the first wheelchair user to go into space when she took a 10-minute trip aboard a Blue Origin rocket.
Blue Origin safely launches wheelchair user to space and back
German engineer Michaela Benthaus is the first person with a significant physical handicap to reach space.
Jared Isaacman, billionaire who's flown with SpaceX, confirmed to lead NASA
President Trump withdrew Isaacman's nomination for NASA administrator in April, before nominating him again in November.
Latest Galleries
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Notable Deaths in 2025
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
More Latest CBS News Videos
Latest CBS News Videos
Why flamingos are returning to Florida
In late 19th-century Florida, hunters pushed flamingos into functional extinction. But something changed over the last 25 years when hurricanes in the Caribbean chased them into the Everglades. Mark Strassmann reports.
Christmas celebrations slowly return to Bethlehem
Thousands traveled from nearby towns and villages to attend Bethlehem's annual tree lighting ceremony in Manger Square -- the first such celebration since 2023. As Imtiaz Tyab reports, there's hope for a brighter future and lasting peace.
Gas leak suspected in deadly nursing home blasts
At least two people were killed, and about 20 others were taken to hospitals, after a gas leak is believed to have sparked two explosions and a fire at a nursing home in Pennsylvania. Lilia Luciano has more on the victims and the investigation.
Burn areas at risk for mudslides in California
The hills of Altadena, California, scorched at the beginning of this year by a wildfire, are now sliding amid heavy rain. Andres Gutierrez spoke to one homeowner who plans to ride out the storm. Andrew Kozak has the forecast.
Heavy rain turns roads to rivers in Los Angeles
The Christmas Eve drive was anything but a holiday gift for many across Los Angeles as heavy rain turned roads into rivers in some areas. At LAX, the last-minute dash to make it home before Christmas had flyers lining up early hoping the storm didn't keep them grounded. Kris Van Cleave reports.