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CHOP pioneered a gene therapy that's already helping patients who have sickle cell disease, an inherited blood disorder.
The search is on for Penn's next president after former president Liz Magill and former chairman of the Board of Trustees Scott Bok resigned over the weekend.
A South Jersey porch pirate was taken into custody on Monday after she eluded police and struck a Gloucester Township police officer with her car.
Steve Sweeney, a former top Democratic lawmaker and New Jersey Senate president, said Monday he's running for governor in 2025.
Philadelphia was awarded $22.4 million from FEMA on Monday to hire 72 new firefighters and reopen three fire companies, President Joe Biden announced.
Bradley Cooper is among the nominees for the 81st annual Golden Globe Awards, but it's unclear if he would prefer an Eagles Super Bowl to a Golden Globe.
District Attorney Larry Krasner and Philadelphia law enforcement officials say they're looking for tips and information on a dozen suspects connected to murders committed over the last four years.
The transit authority will present a final draft for its "Bus Revolution" to the SEPTA Board on Dec. 21, with the hopes of rolling it out in summer 2024.
A storm that began Sunday and led to three record daily rainfall maximums will wrap up Monday morning, but not before a band of light snow pushes through the area.
Two Philadelphia police officers were injured during a shootout in Holmesburg early Sunday morning. For one of the officers, it was the second time they were shot on duty.
Can you read what is written on your dog's face? New research suggests some dog owners can read their pets' expressions.
The Philadelphia Fire Department is receiving a $22.4 million grant to help pay firefighters' salaries and reopen three fire companies.
All eastbound lanes of the Schuylkill Expressway are back open in Montgomery County after a tree fell Sunday night as rain moved across the Philadelphia region.
The Eagles lost to the Cowboys, 33-13, on Sunday night at AT&T Stadium, their second devastating loss in as many weeks as they head into the final stretch of the regular season.
Rain continued through the overnight hours Sunday into Monday in the Philadelphia region and changed to snow in some places. Precipitation will end by mid-morning Monday.
Three people were taken to the hospital after a crash on the Pennsylvania Turnpike eastbound near the Bensalem exit that also caused heavy traffic delays.
SEPTA officials said two men were shot after getting into a fight just before 9 a.m. at the Frankford Transportation Center in Northeast Philadelphia Monday.
Philadelphia Police are investigating the death of a 2-month-old boy in the city's Kensington section. Police said the baby was brought to a hospital just before 2 a.m. Monday following an "incident" at a home on East Birch Street. Hospital staff pronounced the child dead a short time later.
Family and friends of beloved Philadelphia DJ June Rodriguez are pleading for answers after he was killed in a hit-and-run crash while biking home from work early Saturday morning in the city's Overbrook neighborhood.
Emmy-winning artist and musician Bill Jolly is using his sharing his musical gifts with students across Philadelphia this holiday season. For Jolly, performing music is his way of spreading love. "We're here to help others," he says.
John "Johnny Doc" Dougherty, the former Philadelphia union leader in federal prison on bribery and embezzlement charges, is a free man.
The Labor Day holiday weekend is here, and Mother Nature will reward us after a very rough week of weather in the Philadelphia region.
A former staffer confirmed that Sen. John Fetterman has routinely dismissed and at times refused to do core aspects of the job.
Atlanta's Chris Sale outdueled Cristopher Sánchez in a matchup of two of baseball's best pitchers, and the Braves beat the Phillies 5-2 on Friday night to extend their lead in the NL East to five games.
A list of Pennsylvania high school football scores for Sept. 4, 2026.
A Philadelphia mother is on a mission to honor her son's life by pushing to make interstates safer after he was shot and killed on I-95 in March 2025.
John "Johnny Doc" Dougherty, the former Philadelphia union leader in federal prison on bribery and embezzlement charges, is a free man.
A USPS worker was hospitalized after being hit by a vehicle in Northeast Philadelphia, police said.
The family-owned boardwalk shop has become a must-stop destination, serving generations of visitors the same hot cake donuts since 1976.
A signage issue at North Broad Street forced the PPA to refund more than $1.2 million in speed camera violations for more than 12,000 drivers.
A crash on Black Horse Pike in Monroe Township left a 54-year-old man dead and two others injured early Friday morning, police said.
Police believe a group of dirt bike riders deliberately damaged the field at the Mullica Township Recreational Complex and then drove away.
A South Jersey woman who spent nearly $1,000 on Bruno Mars tickets says she finally got her money back after contacting CBS News Philadelphia for help.
The family-owned boardwalk shop has become a must-stop destination, serving generations of visitors the same hot cake donuts since 1976.
While Friday will not be quite as active as the past few days, the Philadelphia region will still need to watch for some late afternoon and Friday evening storms.
While Friday will not be quite as active as the past few days, the Philadelphia region will still need to watch for some late afternoon and Friday evening storms.
More showers and storms will be possible later this afternoon into this evening and bring back the chance for severe weather.
Mantua, New Jersey, was among the hardest hit places in the Philadelphia area after stormy weather swept through on Tuesday night.
The Philadelphia area is under another NEXT Weather Alert on Wednesday for the potential for another round of strong storms.
A tornado warning in Burlington County, New Jersey, was canceled Tuesday night as severe storms hit the Philadelphia region.
A proton therapy treatment being tested at Penn Medicine in Philadelphia could change the future of cancer treatment.
After losing her mother, Sarah Kagan wants to change how employers deal with grief.
Pennsylvania health officials say two people who had measles died in the state, but Health Secretary Robert F. Kennedy Jr. is questioning that.
A Philadelphia police officer taking daraxonrasib for pancreatic cancer says the drug is giving her hope.
Pennsylvania has recorded its first two deaths connected to measles in 35 years.
New Jersey floral designer Alisha Simone Bell said she puts her "whole heart" into every arrangement and every detail.
On Tuesday, Pennsylvania took a major step in the fight against the negative impacts of social media, particularly on children.
Thieves are smashing windows and targeting trading card stores looking for valuable Pokémon cards, police in South Jersey say.
Customers lined up to support Somerdale Cold Cuts as it reopened after a copper theft.
While some assume landlords are required to provide air conditioning, the law is not nearly as clear-cut as it is for heat in the winter
SEPTA is receiving a federal grant worth more than $13 million to replace its aging Silverliner IV Regional Rail fleet.
For the first time in a decade, the Philadelphia Cycling Classic returns this weekend.
Beginning Sunday, several bus routes in Philadelphia are changing, including the addition of two new routes.
A deadly crash in Warminster is under investigation Sunday, police said.
PennDOT is advising drivers about an overnight closure on the Schuylkill Expressway westbound in West Philadelphia between 30th Street and the interchange with I-676 East.
Atlanta's Chris Sale outdueled Cristopher Sánchez in a matchup of two of baseball's best pitchers, and the Braves beat the Phillies 5-2 on Friday night to extend their lead in the NL East to five games.
A list of Pennsylvania high school football scores for Sept. 4, 2026.
Ben Simmons agreed to a one-year deal with the Sacramento Kings, marking a return to the NBA for the former No. 1 draft pick.
Lawyers for former Penn State assistant football coach Jerry Sandusky are asking to cancel a hearing related to an accuser recanting his claims.
The Philadelphia Phillies saw their six-game losing streak end Wednesday with a 1-0 loss to the Arizona Diamondbacks.
"Sunday Morning" looks back at the astonishing career of the queen of country music, whose talent, warmth, wit, and philanthropy made her a genuine, once-in-a-generation luminary.
Three AMC Theatres in the Philadelphia region are holding special screenings to celebrate the life and legacy of Dolly Parton.
Stella Parton said her sister Dolly told her "that if there was no hope for her, she would still allow her medical team to try experimental drugs in the hope of helping others in the future."
Tim Curry was known for his iconic performances in cult classics like "The Rocky Horror Picture Show" and the original screen adaptation of Stephen King's "It."
Hosts Nicole Michalik and Patty Jackson react after country music icon Dolly Parton dies at age 80.
Ukee Washington reports.
Natasha Brown reports.
Natasha Brown reports.
Natasha Brown reports.
Ukee Washington reports.
Middle school students in Philadelphia got the opportunity to do hands-on learning during the school district's five-day career and technical camp.
With her Girl Talk mentoring program, one Philadelphia teen turned her camp days into a safe space to discuss social issues young girls face every day.
Recent high school graduate Sylvain Farrell says his temporary position at a local clinic is the pathway to a full-time career.
A Philadelphia student won an award from NFL Films for his documentary on bringing back sports teams at his Kensington school.
A group of East Norriton eighth graders took what started as an Earth Day project and made a whole initiative.
Bill Kelly says Saturday in the Philadelphia region will be less humid. Here's the NEXT Weather forecast for a beautiful Labor Day weekend.
The Phillies lost 5-2 to the Braves in the first game of a four-game series Friday night, but fans are still hopeful for the rest of the games.
John Dougherty was released Friday afternoon after he served less than a third of his six-year sentence, his lawyer said.
Whether it's your first beach day or you've been creating memories and family traditions in Ocean City, New Jersey, for years, Labor Day weekend is the unofficial end of summer for many. Reporter Siafa Lewis talked to families about their plans.
The unofficial end of summer is nearly here, but reporter Siafa Lewis is soaking in the final taste of the season with some sweet treats from Shriver's Salt Water Taffy and Fudge along the boardwalk in Ocean City, New Jersey.