Philadelphia doctors use gene editing therapy to treat child with rare disease for the first time
The CRISPR gene editing therapy has been used for other diseases like sickle cell, but this is the first time it's been customized for one patient.
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The CRISPR gene editing therapy has been used for other diseases like sickle cell, but this is the first time it's been customized for one patient.
The first patient to receive a new gene therapy at the Children's Hospital of Philadelphia is now living pain-free for the first time.
A new gene therapy, developed at the Children's Hospital of Philadelphia, has been approved by the FDA and is being used to transform lives.
Authorities said Michael Vahey was intoxicated when he struck Barbara Friedes, who was biking on Spruce Street, in July 2024.
Natalie Dormer stars in "Audrey's Children" as Dr. Audrey Evans, a CHOP doctor who co-founded Ronald McDonald House Charities.
Audrey Evans was the co-founder of the Ronald McDonald House and a pediatric oncologist at Children's Hospital of Philadelphia. Natalie Dormer, who you might recognize from "Game of Thrones" or "Elementary" plays Evans in the new film "Audrey's Children." Stephanie Stahl reports.
A measles case was detected in a person who recently visited multiple Children's Hospital of Philadelphia facilities, health officials said.
Philadelphia health officials are warning that a child who has measles could have exposed other people to the highly contagious virus at two locations in the city.
Ridley High School's R-Thon raises money and awareness for childhood cancer and cardiac research at Children's Hospital of Philadelphia.
Cleats worn by Eagles quarterback Jalen Hurts are being auctioned off to benefit Children's Hospital of Philadelphia through the NFL's "My Cause, My Cleats" program.
The world's smallest heart pump helped save a Children's Hospital of Philadelphia patient's life. Now that it's been FDA-approved for younger children, doctors say it will help even more.
New high-tech help for young heart patients has been approved by the U.S. Food and Drug Administration. Doctors say this will allow them to save more lives, an important milestone as we kick off American Heart Month.
A brain surgeon at Children's Hospital of Philadelphia has a mission to make cheerleading safer with the Stunt Showdown at Haverford College on Dec. 21.
Making cheerleading safer is the mission of a brain surgeon at Children's Hospital of Philadelphia. Stephanie Stahl reports the new competition that has started.
A Florida family who stays at the Ronald McDonald House while their baby boy gets treatment for OEIS complex calls the community they've met family.
Brailey Valenzuela became the fourth patient at CHOP to successfully undergo this type of fetal heart surgery.
The Children's Hospital of Philadelphia has successfully performed a historic fetal surgery to remove a heart tumor, saving the life of a fetus from Tennessee. Stephanie Stahl reports.
"Tabletop for CHOP" is using Dungeons and Dragons and other tabletop games to raise money for Children's Hospital of Philadelphia.
The babies in the NICU at Children's Hospital of Philadelphia won't be home this Halloween but here's hoping they are healthy and happy for next year. In the meantime, CHOP is still getting the little ones in the holiday spirit.
A group of Philadelphia middle schoolers got an inside look at anesthesiology from local doctors.
CHOP has now performed 32 conjoined twin separations, the most of any hospital in North America.
A Philadelphia family is reunited as conjoined twins are now home after being successfully separated and spending a year at Children's Hospital of Philadelphia. Stephanie Stahl.
Thousands of people are taking over the Benjamin Franklin Parkway in Philadelphia for the annual CHOP Parkway Run and Walk, which raises money to help children fight cancer. This year's goal is to raise $2 million for pediatric cancer research.
With the Sweet Dream Project, Ayana Banks helps transform regular hospital rooms at CHOP into patients' dream rooms.
There's new hope for people with sickle cell disease which affects mainly African Americans. It's gene therapy research at Children's Hospital of Philadelphia that's being called a game changer.
Carlos Della Valle is home with his family in Chester County after 258 days in Immigration and Customs Enforcement custody.
Joel Embiid will return to the lineup for Game 3 of the Eastern Conference semifinals vs. the New York Knicks Friday in Philadelphia.
Zayla Dutton and her mom, Jasmine Worrell, are getting ready to graduate from college together.
Chefs are busy getting ready to serve thousands of spectators at Aronimink Golf Club during the PGA Championship.
Quakertown Police Chief Scott McElree will not face discipline for a February altercation with teens, borough officials say.
Carlos Della Valle is home with his family in Chester County after 258 days in Immigration and Customs Enforcement custody.
Joel Embiid will return to the lineup for Game 3 of the Eastern Conference semifinals vs. the New York Knicks Friday in Philadelphia.
Zayla Dutton and her mom, Jasmine Worrell, are getting ready to graduate from college together.
Chefs are busy getting ready to serve thousands of spectators at Aronimink Golf Club during the PGA Championship.
Quakertown Police Chief Scott McElree will not face discipline for a February altercation with teens, borough officials say.
Carlos Della Valle is home with his family in Chester County after 258 days in Immigration and Customs Enforcement custody.
Zayla Dutton and her mom, Jasmine Worrell, are getting ready to graduate from college together.
Chefs are busy getting ready to serve thousands of spectators at Aronimink Golf Club during the PGA Championship.
Quakertown Police Chief Scott McElree will not face discipline for a February altercation with teens, borough officials say.
The Phillies surprised and honored Boothwyn Elementary School physical education teacher Scott Messick during a special event at the school on Friday.
A child died after being hit by a school bus in Greenwich Township, New Jersey, Friday afternoon, police said.
Resistance to data centers has been building over concerns about power and water usage, as well as neighborhood character.
Two New Jersey residents were potentially exposed to a person infected with hantavirus, according to health officials.
The largest collegiate regatta in the United States is back again on the Cooper River in Camden County, New Jersey.
A serious crash in Hainesport, New Jersey, forced Route 38 to close Thursday night.
A New Castle County, Delaware, refinery is starting repairs that could increase its sulfur dioxide emissions levels past permitted limits.
At 108 years old, Susan Young Browne still exercises, drives and visits the Dover, Delaware, senior center she's been a member of for more than 50 years.
Delaware State University students are taking off from Chandelle Airport in Dover as they work to become future Army aviators.
Crews were called out to the 2000 block of North Harrison Street for a reported blaze at a three-story building.
Jimmie Hayes was arrested in connection with at least nine burglaries at businesses in Wilmington, Delaware, police said.
The Centers for Disease Control and Prevention has activated its 24/7 emergency center in Atlanta to monitor the recent deadly hantavirus outbreak onboard the MV Hondius.
Two New Jersey residents were potentially exposed to a person infected with hantavirus, according to health officials.
Philadelphia church leaders are encouraging Black women to participate in a groundbreaking health study.
A Bensalem family visited the team at Jefferson Abington Hospital to say thank you after a long NICU stay.
The rare genetic disorder neurofibromatosis, or NF, affects about 1 in every 3,000 people and causes tumors to grow along nerves throughout the body.
If you dine out in Philadelphia during the 2026 FIFA World Cup events, you could end up paying more.
Bimbo Bakeries USA employs over 20,000 people and has been headquartered in Horsham, Pennsylvania, for the past 17 years.
Photos by HughE Dillon
Gas prices are climbing, putting a strain on the transportation industry and its workers in the Philadelphia area.
FIFA officials have canceled hundreds of hotel rooms in Philadelphia previously booked for this summer.
A serious crash in Hainesport, New Jersey, forced Route 38 to close Thursday night.
The ramp from Front Street to northbound I-95 and the ramp from southbound I-95 to Front Street will reopen the afternoon of May 8 until the morning of May 11.
Breeze Airways launched its first flights out of Atlantic City International Airport just days after Spirit Airlines shut down suddenly.
The sudden shutdown of Spirit Airlines is having an outsized impact on Atlantic City International Airport, where the budget carrier accounted for about 75% of all flights.
The former Greyhound Bus Terminal, now called the Philadelphia Parking Authority Transportation Center, has reopened after undergoing a major renovation project.
Joel Embiid will return to the lineup for Game 3 of the Eastern Conference semifinals vs. the New York Knicks Friday in Philadelphia.
The Sixers say 500 tickets for each game at Xfinity Mobile Arena in their second-round series will go to Philadelphia area fans.
The largest collegiate regatta in the United States is back again on the Cooper River in Camden County, New Jersey.
The Flyers are on the brink of elimination after losing Game 3 to the Hurricanes on Thursday night at Xfinity Mobile Arena.
The Philadelphia Phillies were crushed by the Athletics Thursday night to avoiding a three-game sweep.
Uzo Aduba and Darren Criss announced the 2026 Tony nominees for select categories on "CBS Mornings" on Tuesday.
If you dine out in Philadelphia during the 2026 FIFA World Cup events, you could end up paying more.
Call Your Mother, a Washington D.C. based bagel and deli chain, now has the keys to Metropolitan's Rittenhouse Square location.
The Philadelphia Museum of Art is embracing a statue it once kept at arm's length.
The "Dog Days Are Over" for the Flyers, but their return to the playoffs comes at the cost of the Florence + the Machine concert.
Ukee Washington reports.
Natasha Brown reports.
Natasha Brown reports.
Natasha Brown reports.
Ukee Washington reports.
Middle school students in Philadelphia got the opportunity to do hands-on learning during the school district's five-day career and technical camp.
With her Girl Talk mentoring program, one Philadelphia teen turned her camp days into a safe space to discuss social issues young girls face every day.
Recent high school graduate Sylvain Farrell says his temporary position at a local clinic is the pathway to a full-time career.
A Philadelphia student won an award from NFL Films for his documentary on bringing back sports teams at his Kensington school.
A group of East Norriton eighth graders took what started as an Earth Day project and made a whole initiative.
Lauren Morris, who won the 2025 Trudy Haynes Scholarship from CBS News Philadelphia, spoke at her graduation from Temple University's Klein College of Media and Communication on Friday. She plans to pursue a career in journalism.
The Philadelphia region is under a NEXT Weather alert Saturday for strong winds, hail and heavy rain. Meteorologist Bill Kelly has the forecast.
Carlos Della Valle, who has lived in Downingtown, Pennsylvania, for decades, recently returned home to his family after months in Immigration and Customs Enforcement custody. He says he came to the United States at age 20 because he was fleeing cartel violence.
Law enforcement officials say security plans in Philadelphia for the FIFA World Cup matches and July 4 celebrations will be similar to those for the Eagles' Super Bowl parades.
Ethan Hsu, a junior at Harriton High School in Bryn Mawr, Pennsylvania, recently entered and won a Pittsburgh Symphony Orchestra music composition contest — open to all ages — and heard the orchestra perform his piece.