FDA approves gene-editing treatment for sickle cell disease
Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
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Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
An estimated one in eight women will develop breast cancer in their lifetime, killing on average 42,000 a year in the U.S. But what if a vaccine could significantly lower each woman's chance of ever getting it in the first place?
Pediatricians are seeing an increase in pediatric cases of respiratory viral infections and the flu, Allegheny Health Network says.
With all the food, drink, candy, and parties, it's easy to let go during the holidays, but it is avoidable while still enjoying it.
Casual dining chain faces another wrongful death suit related to its Charged Lemonade after cardiac arrest of Florida man.
The American Academy of Pediatrics is sounding the alarm on excessive noise that kids and teens are exposed to.
State Rep. Arvind Venkat's bills would help promote food safety at restaurants across the commonwealth.
It's the time of year when the trees go up, the lights get lit, and sadly, people get hurt.
Clementine Blackham needed a rare, life-saving bone marrow transplant which she eventually received.
The "Charmed" and "Beverly Hills, 90210" actor said she hopes to get into clinical trials as new treatments are developed but what drives her now is the desire "to prove" that she can work despite her cancer diagnosis.
The tests will be available from a federal stockpile starting in December, and schools can distribute them to students, families, staff and larger school communities.
Recalled Burn Boot Camp snacks were sold at locations run by gym franchises throughout the U.S.
FDA finds reasonable expectation of effectiveness for drug designed to keep bigger breeds around longer, biotech firm says.
It's inevitable that people get sick during the holidays -- but how long is it before you're out of the woods?
A local boutique donated hundreds of cardigans to the Metastatic Breast Cancer Center at Allegheny General Hospital.
An Allegheny County woman is facing theft charges after police said she stole more than $4,000 from a scholarship fund created to honor a fallen McKeesport police officer.
A homeowner and her children locked themselves inside a bathroom while a suspected burglar was inside their Pennsylvania home.
NFL player Miles Sanders was arrested in the Pittsburgh area for driving under the influence, according to court records.
UPMC is taking another step to help Pittsburgh's first responders better protect our community.
The San Diego Padres beat the Pittsburgh Pirates 3-0 on Wednesday to avoid a three-game sweep.
A federal judge on Tuesday temporarily blocked enforcement of an Ohio requirement that voters show proof of citizenship when registering to vote at a motor vehicle bureau
Data centers have become the hottest issue in political races across the country, including Pennsylvania's race for governor.
The U.S. and Canada have wrangled for decades over trade, and somehow, they still managed to remain friends, allies and trading partners.
Veteran organizations and businesses are asking state legislators to pass a bill allowing them to keep their so-called "skill-game" machines.
"We've seen too many developers who are trying to bulldoze our community," Pennsylvania Gov. Josh Shapiro told "CBS Mornings."
A new report tries to calculate how much Pennsylvanians need to earn to live what's considered a comfortable lifestyle.
The store is expected to open sometime next year.
Buffalo Township police are warning about scammers after investigating several cases where residents have fallen victim.
On Tuesday, Pennsylvania took a major step in the fight against the negative impacts of social media, particularly on children.
While the importance of the family support system is timeless, a new study found it creates financial stressors for all involved.
A local author talks about her new book, "The Red Line," which explains red flags and how to spot them.
The Pittsburgh Pie Guy shows David and Mikey how to make one of his popular hand-pies.
The Children's Museum is sharing more about its special event that is bringing the world of Gabby's Dollhouse to life.
Daisy previews one of the city's biggest parties by heading to the rooftop terrace at the David L. Lawrence Convention Center.
This month's Community Hero is a high school student with a passion for giving back. He founded a nonprofit that gives back to our active-duty military.
An attempt to regulate Pennsylvania's pet cremation industry just hit a wall.
A family in Wall Borough, Allegheny County, said repeated flooding has forced them to abandon their home's first floor.
A downed power line turned a Kittanning family's front yard into a dangerous scene.
More than 300 Pittsburgh Public Schools buses are equipped with AI-enabled Bus Patrol cameras.
The Bob O'Connor Golf Course has been run by a nonprofit with a charitable mission, but the course has been losing money.
UPMC is taking another step to help Pittsburgh's first responders better protect our community.
For the first time since 1991, Pennsylvania has recorded its first two deaths connected to measles.
Pennsylvania has recorded its first two deaths connected to measles in 35 years.
Injuries are a part of many sports, and UPMC is trying to help high school athletes get back to the games they love.
More than three years later, we're beginning to learn about the health impacts of the Norfolk Southern train derailment in East Palestine, Ohio.
The San Diego Padres beat the Pittsburgh Pirates 3-0 on Wednesday to avoid a three-game sweep.
NFL player Miles Sanders was arrested in the Pittsburgh area for driving under the influence, according to court records.
Oneil Cruz hit the first homer allowed by Mason Miller in over a year with two outs in the ninth, sending the Pittsburgh Pirates to a 1-0 victory over San Diego.
San Francisco 49ers owner Jed York has pleaded no contest to two misdemeanor charges in Northeast Ohio after being arrested on suspicion of engaging in prostitution over the weekend, authorities said.
Nick Gonzales led off the 12th inning with an RBI single and the Pittsburgh Pirates snapped their three-game skid with a 3-2 victory over the San Diego Padres.
A federally funded Ohio manufacturing program faces potential shutdown after a new audit by the U.S. Department of Commerce's Office of Inspector General.
Gas station giant Buc-ee's has sparked a backlash in Ohio over one of its frequent trademark infringement lawsuits.
The international fashion retailer Zara will open a location in Ross Park Mall in 2028, as the mall continues to thrive.
Some Bloomfield business owners paint a nuanced picture of how the annual Little Italy Days festival impacts them, saying that while they don't dislike the festival, they do make less money than they normally would.
The store is expected to open sometime next year.
Tim Curry was known for his iconic performances in cult classics like "The Rocky Horror Picture Show" and the original screen adaptation of Stephen King's "It."
Pittsburghers are remembering Dolly Parton as "one of a kind" following her death on Tuesday.
Dolly Parton became an icon over her six-decade career as a Grammy-winning singer-songwriter, movie and TV star and theme park owner who donated millions to help others.
Bret Michaels is taking a break from touring to recover from recent surgeries.
The Jonas Brothers are returning to Pittsburgh later this year.
A man will face charges after a 62-year-old man was killed in a hit-and-run crash in Redstone Township, Fayette County, authorities said.
UPMC is taking another step to help Pittsburgh's first responders better protect our community.
Stay on top of the weather in the Pittsburgh area with First Alert Meteorologist Ray Petelin's forecast!
Dr. Natalie Gentile is with us to talk about postpartum health, what to look for and how to find support.
Every once in a while, you need to trade the Three Rivers for the Atlantic Ocean! Karyn Locke is sharing why a trip to Virginia Beach could be the perfect escape.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
