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Man with autism reported missing in Harlem

There's a desperate search to find a missing Harlem man who has autism. Isaac Wilkie, 20, was last seen by his mom Monday evening at their home.

Aug 7 (00:57)

First Alert Weather: Heavy rain for New York on Sunday – 10/10/26

First Alert Weather: Heavy rain for New York on Sunday – 10/10/26

Starfish smoked seafood Trio recalled over possible Listeria contamination

Starfish smoked seafood Trio recalled over possible Listeria contamination

ICE agents arrest man in Harrison, NJ

ICE agents arrest man in Harrison, NJ

Family of Bronx mother killed in balcony push speaks out

Family of Bronx mother killed in balcony push speaks out

1 dead in Staten Island apartment fire

1 dead in Staten Island apartment fire

3 injured after car flips on side in Midtown Manhattan

3 injured after car flips on side in Midtown Manhattan

4 dead as weakened Isaias brings threat of floods across the Southeast

4 dead as weakened Isaias brings threat of floods across the Southeast

Woman killed in wrong-way crash on Staten Island Expressway

Woman killed in wrong-way crash on Staten Island Expressway

How a nonprofit is helping people with disabilities get service dogs

How a nonprofit is helping people with disabilities get service dogs

Los Angeles County search and rescue deployed to Panama after powerful earthquakes

Los Angeles County search and rescue deployed to Panama after powerful earthquakes

Attack on Saudi Arabia's international airport kills 12, Saudi authorities say

Attack on Saudi Arabia's international airport kills 12, Saudi authorities say

Gunman charged with killing officer, wounding another in Philadelphia

Gunman charged with killing officer, wounding another in Philadelphia

Nine dead, including 2 children, in East Erie Pennsylvania shooting

Nine dead, including 2 children, in East Erie Pennsylvania shooting

Isaias causes damage in Florida, cleanup underway

Isaias causes damage in Florida, cleanup underway

First Alert Weather: Isaias remnants to soak New York on Sunday – 10/10/26

First Alert Weather: Isaias remnants to soak New York on Sunday – 10/10/26

Hundreds gather in Herald Square as anti-ICE protests continue in NYC

Hundreds gather in Herald Square as anti-ICE protests continue in NYC

Vigil held for mother who died after being pushed off balcony in Bronx

Vigil held for mother who died after being pushed off balcony in Bronx

New York Comic Con at Javits Center | Full coverage

New York Comic Con at Javits Center | Full coverage

Officer fired weapon while responding to slashing in Queens, police say

Officer fired weapon while responding to slashing in Queens, police say

Judge temporarily blocks deportation of man shot by ICE agent in NYC

Judge temporarily blocks deportation of man shot by ICE agent in NYC

First Alert Weather: Soggy Sunday ahead in New York - 10/10/26

First Alert Weather: Soggy Sunday ahead in New York - 10/10/26

Why do New Yorkers call 311, and do they actually respond?

Why do New Yorkers call 311, and do they actually respond?

Rep. Nicole Malliotakis and Mike DeCillis | The Point Full Episode 10.10.26

Rep. Nicole Malliotakis and Mike DeCillis | The Point Full Episode 10.10.26

Latest on Marble Hill ICE shooting investigation

Latest on Marble Hill ICE shooting investigation

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