49ers' Trent Williams and Ricky Pearsall miss crucial game against Seahawks with injuries
San Francisco 49ers Pro Bowl left tackle Trent Williams and receiver Ricky Pearsall missed the Week 18 game against the Seattle Seahawks due to injuries.
Watch CBS News
San Francisco 49ers Pro Bowl left tackle Trent Williams and receiver Ricky Pearsall missed the Week 18 game against the Seattle Seahawks due to injuries.
The Seattle Seahawks and San Francisco 49ers face off in a high-stakes game on Saturday night.
Quarterback Drew Brees and wide receiver Larry Fitzgerald headline the list of modern era finalists for the Pro Football Hall of Fame.
Brock Purdy threw a 38-yard touchdown pass to Jauan Jennings with 2:15 to play, and the San Francisco 49ers forced an incomplete pass on the final play from the 2 to beat the Chicago Bears 42-38 and set up a Week 18 showdown for the top seed in the NFC.
Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead the San Francisco 49ers to a 48-27 victory at Indianapolis.
Brock Purdy threw three touchdown passes as the San Francisco 49ers beat the Tennessee Titans 37-24.
The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return from a knee injury this season.
The San Francisco 49ers announced Wednesday that OpenAI chairman Bret Taylor has acquired a minority stake in the team, joining other tech titans that have bought into the club.
Brock Purdy rushed for a touchdown and passed for another score in the second half, and the San Francisco 49ers spoiled Shedeur Sanders' first home start with a 26-8 victory over the Cleveland Browns.
Shedeur Sanders isn't focused on the buzz around his relationship with coach Kevin Stefanski or the cheers expected when he plays against San Francisco.
Carolina Panthers safety Tre'von Moehrig has been suspended one game without pay for punching San Francisco 49ers wide receiver Jauan Jennings in the groin during Monday's game.
Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago.
The San Francisco 49ers are back in playoff contention with Brock Purdy returning as their starting quarterback.
Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly two years.
Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and a receiving score, and the San Francisco 49ers beat the sloppy Arizona Cardinals 41-22.
Quarterback Brock Purdy returns to the starting lineup for the San Francisco 49ers this week after missing six games with a toe injury.
San Francisco 49ers quarterback Brock Purdy is set for an aggressive practice on Wednesday.
Matthew Stafford throws four touchdown passes, setting a Rams franchise record for the most in a three-game span.
During his tenure from 1989 to 2006, Paul Tagliabue oversaw the expansion of the NFL to 32 teams.
The San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee injury.
Former NFL star Antonio Brown was extradited from Dubai to the U.S. to face attempted murder charges in a Miami shooting outside a boxing event.
The National Football League and Bay Area Host Committee announced a list of official events in the San Francisco Bay Area in the week leading up to Super Bowl LX in February, culminating with the game at Levi's Stadium.
Victor Conte, the architect of a scheme to provide undetectable performance-enhancing drugs to professional athletes decades ago, has died.
San Francisco 49ers defensive lineman Mykel Williams will miss the rest of the season after the first-round pick was diagnosed with torn ligaments in his right knee.
McCaffrey caught a touchdown pass from Jones, rushed for another score and the 49ers got back on track by running all over the Giants in a 34-24 victory on Sunday.