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The San Francisco 49ers travel to Florida to face the Tampa Bay Buccaneers for NFL Week 6, and there are several ways to watch and stream the football game scheduled at 4:25 p.m. ET / 1:25 p.m. PT.
Quarterback Brock Purdy will miss his fourth game this season for San Francisco due to a toe injury.
Eddy Piñeiro has quickly become a fan favorite with the San Francisco 49ers.
San Francisco 49ers quarterback Brock Purdy is still sidelined by a toe injury and missed practice on Wednesday.
Eddy Piñeiro hit a 41-yard field goal in overtime before the San Francisco defense stopped Kyren Williams on fourth down with 3:36 to play, and the short-handed 49ers hung on for a thrilling 26-23 victory over the Los Angeles Rams on Thursday night.
The injury-ravaged San Francisco 49ers will again be missing multiple starters with injuries for the Thursday night game against the Los Angeles Rams.
Quarterback Brock Purdy is dealing with a toe injury that has sidelined him for two games this season.
The San Francisco 49ers are dealing with injuries following their first loss of the season to the Jacksonville Jaguars.
Parker Washington has scored Jacksonville's first punt return touchdown in eight seasons, leading the Jaguars to a 26-21 victory over the San Francisco 49ers.
Quarterback Brock Purdy returns for the San Francisco 49ers this week after missing two games with a toe injury.
The San Francisco 49ers have been winning games despite struggling with their usual ground game.
San Francisco 49ers star defensive lineman Nick Bosa will miss the rest of the season with a torn anterior cruciate ligament, the team confirmed Monday.
San Francisco 49ers star Nick Bosa left the win against the Arizona Cardinals with a knee injury.
Eddy Pineiro has kicked a 35-yard field goal to give the San Francisco 49ers a 16-15 win over the Arizona Cardinals.
Quarterback Brock Purdy is highly unlikely to start for the San Francisco 49ers on Sunday because of a toe injury.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
Pinch-hitter Ty France delivered a two-run triple in the seventh inning to put San Diego ahead to stay as the Padres picked up a 5-1 win over the San Francisco Giants on Wednesday.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
With yet another top-five pick, GM Mike Grier and his staff can augment a young group already led by Macklin Celebrini and including Will Smith and Michael Misa.
Jackson Merrill had three hits and drove in two runs, Xander Bogaerts homered and the San Diego Padres tied their season highs for hits with 14 and runs in a 10-5 victory over the San Francisco Giants.
Jonathan Aranda hit a game-ending single in the 10th inning to cap a 4-for-5 afternoon, and the Tampa Bay Rays beat the San Francisco Giants 2-1 to complete a three-game sweep.
Jonathan Aranda hit a two-run single in Tampa Bay's three-run fifth inning and the Rays defeated the San Francisco Giants 5-1.
Cherie DeVaux became the first woman to train the winner of the opening leg of the Triple Crown.
Yandy Diaz and Junior Caminero homered to back six strong innings from Shane McClanahan and the Tampa Bay Rays beat the San Francisco Giants 3-0 on Friday night.
Drivers who are planning to use 19th Avenue in San Francisco this Mother's Day weekend should expect delays, as southbound lanes of the roadway are closed for repaving work.
Hiring once again exceeded forecasts, with employers adding far more than the projected gains of 65,000.
Gov. Gavin Newsom defended his administration's water policies and pushed for major infrastructure projects, including the controversial Delta Conveyance Project, arguing California is now "more prepared for our water future than ever before."
From its headwaters high in the Oakland Hills throught the city's Fruitvale District to where the waters eventually empty into the Oakland Estuary and San Francisco Bay, Sausal Creek is a historic treasure.
A system that thousands of schools and universities use was offline due to a cyberattack.
Drivers who are planning to use 19th Avenue in San Francisco this Mother's Day weekend should expect delays, as southbound lanes of the roadway are closed for repaving work.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
Authorities on the Peninsula said five human trafficking survivors were rescued and one person was detained as part of a nationwide operation.
Two Southern California residents suspected of multiple felony and misdemeanor crimes and were arrested after a traffic stop in the Bay Area on Sunday evening, authorities said.
A coyote that gained international attention after it was spotted swimming in frigid San Francisco Bay and arriving at Alcatraz Island earlier this year began its epic swim farther away than initially assumed, according to the National Park Service.
From its headwaters high in the Oakland Hills throught the city's Fruitvale District to where the waters eventually empty into the Oakland Estuary and San Francisco Bay, Sausal Creek is a historic treasure.
The 2025 death of a 72-year-old woman in Brentwood who had a medical emergency after being forcibly placed into police custody will be the subject of a formal inquiry, authorities said.
Police in Oakland said nearly two dozen people have been charged so far in connection with Sunday's takeover of the Bay Bridge by dozens of riders on ATVs and dirt bikes.
For more than 20 years, a Pleasanton woman has provided special handmade gifts of comfort to children in crisis.
California lawmakers are considering a bill that would ensure insurance companies cover the cost of scalp cooling technology for cancer patients.
The owner of a business on California's Central Coast has been arrested after he allegedly sexually assaulted a customer during what police described as a "spiritual cleansing."
During Asian American and Pacific Islander Heritage Month, we want to highlight the life and legacy of Japanese American Takayoshi "Dick" Miyagawa.
A man who shot a Mountain View police officer at point blank range during a traffic stop in 2022 was found guilty of attempted murder, authorities said.
A hospital in Santa Clara County is working to find the source of contamination that led to several people being infected by Legionella bacteria.
A shooting at an apartment complex in San Jose left one person dead and the shooter was at large, police said.
Two former Rohnert Park police officers were sentenced to prison on Wednesday for their roles in a marijuana extortion scheme in which they posed as federal agents, prosecutors said.
Police in Santa Rosa have made one arrest and are looking for additional suspects following a shooting near a Cinco de Mayo festival Tuesday night.
In the North Bay, tractors have been commonly used to trim down dry brush, but grazing is now gaining popularity.
After years of devastating wildfires, droughts, and floods, many North Bay communities banned new gas stations as part of an effort to fight climate change. But the Town of Windsor may be making a U-turn.
Just before 8:30 p.m., officers near Sebastopol Road and Avalon Avenue heard multiple gunshots coming from Dutton Avenue, just outside of the festival area.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
Pinch-hitter Ty France delivered a two-run triple in the seventh inning to put San Diego ahead to stay as the Padres picked up a 5-1 win over the San Francisco Giants on Wednesday.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
With yet another top-five pick, GM Mike Grier and his staff can augment a young group already led by Macklin Celebrini and including Will Smith and Michael Misa.
Jackson Merrill had three hits and drove in two runs, Xander Bogaerts homered and the San Diego Padres tied their season highs for hits with 14 and runs in a 10-5 victory over the San Francisco Giants.
The 2025 death of a 72-year-old woman in Brentwood who had a medical emergency after being forcibly placed into police custody will be the subject of a formal inquiry, authorities said.
The owner of a business on California's Central Coast has been arrested after he allegedly sexually assaulted a customer during what police described as a "spiritual cleansing."
Police in Oakland said nearly two dozen people have been charged so far in connection with Sunday's takeover of the Bay Bridge by dozens of riders on ATVs and dirt bikes.
Two former Rohnert Park police officers were sentenced to prison on Wednesday for their roles in a marijuana extortion scheme in which they posed as federal agents, prosecutors said.
Police in Santa Rosa have made one arrest and are looking for additional suspects following a shooting near a Cinco de Mayo festival Tuesday night.
A system that thousands of schools and universities use was offline due to a cyberattack.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
A proposed $250 million settlement would compensate millions of consumers who bought the iPhone 16, iPhone 15 Pro or iPhone 15 Pro Max.
Career experts say workers and job seekers should take charge of their own AI education. Here's how to get started.
EBay said on Monday that it will "carefully review" GameStop's unsolicited $ 125-per-share takeover offer.
Mexican street corn-inspired trail mix made by Illinois food company was sold at Target and other retailers, as well as online.
A hospital in Santa Clara County is working to find the source of contamination that led to several people being infected by Legionella bacteria.
Three passengers have been evacuated from a cruise ship hit by a hantavirus outbreak, as related cases are confirmed in Switzerland and South Africa.
The FDA announced its first authorization of fruit-flavored electronic cigarettes intended for adult smokers, a major policy shift after months of appeals to President Trump from the vaping industry.
An ice cream company based in the San Francisco Bay Area is recalling dozens of products after they were sold without labels disclosing potentially dangerous allergens.
The Justice Department argues the patchwork of state laws around guns makes it difficult to take them across state lines for lawful purposes like target shooting, hunting and self-defense.
Three U.S. Navy destroyers transiting the Strait of Hormuz came under attack on Thursday, and the U.S. struck on two Iranian ports abutting the strait, putting into question an increasingly fragile U.S.-Iran ceasefire.
Congressional Democrats are investigating clemency recipients who may have obtained favorable treatment from Trump or his advisers "through intermediaries, financial contributions, or other forms of influence."
A former cellmate has previously claimed that the note was written by Epstein after a failed suicide attempt less than a month before his death.
The FDA announced its first authorization of fruit-flavored electronic cigarettes intended for adult smokers, a major policy shift after months of appeals to President Trump from the vaping industry.
Philz Coffee will once again sport the Pride flag at its cafés after a directive to have them and other flags removed created a backlash.
The Trump administration agreed to restore the Stonewall National Monument's Pride flag in Greenwich Village after it was removed.
Philz Coffee's move to remove the Pride flag and all other flags from their stores is brewing up some strong reaction.
Transgender women athletes are now excluded from women's events at the Olympics after the IOC agreed to a new eligibility policy on Thursday.
The Trump administration has given San Jose State University 10 days to change its policy on transgender athletes or face legal action and possibly lose federal funding.
Rihanna, Sabrina Carpenter, Madonna, and Beyoncé all wore their best looks to celebrate the "Costume Art" theme at the 2026 Met Gala. Here are some of the best moments, photos, and more from the night.
At Last Rites, the weekly gathering goes beyond simply watching a television show. For fans, it's an immersive experience, one that brings them closer to the world of "Survivor," and to each other.
Jake was at the funeral for one of his closest friends when he learned of his parents' deaths, he said.
Michael Tilson Thomas, the 12-time Grammy Award winning composer and famed conductor who led the San Francisco Symphony for a quarter century, has died.
Pop star Britney Spears has voluntarily checked into rehab following her DUI arrest in Ventura County in March, a representative for the singer told CBS LA.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Andrea Nakano reports.
For 30 years, Friends of Sausal Creek has restored miles of habitat, planting tens of thousands of native flowers, trees, shrubs, and grasses. Anne Makovec reports.
Friday morning marks the next phase of Caltrans' project to resurface 19th Avenue in San Francisco's Sunset District. Veronica Macias report.
If a hotel tax measure fails on the June ballot, San Jose residents could lose Sunday library hours and downtown police patrols amid a $50 million budget shortfall. Kevin Ko reports.
A high-tech way to train for wildfires could be the future for crews across California. Itay Hod has a behind-the-scenes look at a new kind of preparation for fires in the wildland-urban interface.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
