J.J. McCarthy was knocked out of the Minnesota Vikings' game against the New York Giants on Sunday with an injury to his throwing hand and did not return.

McCarthy was crushed by unblocked pass rusher Brian Burns on a strip sack with 24 seconds remaining in the first half. The 22-year-old quarterback walked off the field with trainers after the play that resulted in a fumble recovery and a touchdown for the Giants.

Rookie backup Max Brosmer replaced McCarthy. The Vikings went on to beat the Giants 16-13. 

After the game, head coach Kevin O'Connell said he had no update on McCarthy's injury.

"We'll evaluate it and make sure we find out what's going on there," O'Connell said.

The head coach said he was encouraged by the young quarterback's play before the injury.

"I thought J.J. was doing a lot of really good things and really, really unfortunate that he was not able to finish the football game," O'Connell said. "He was, in my opinion, stacking — putting together a very nice performance again."

McCarthy missed a game late last month while in concussion protocol and has also been sidelined by a sprained right ankle after his entire rookie year was wiped out by a torn meniscus in his right knee.

McCarthy was 9 of 14 for 108 yards passing, ran for a TD and had a would-be pick-6 negated by penalty before getting hurt in a game that has no playoff implications. The 7-8 Vikings were eliminated before beating Dallas last weekend, and the 2-13 Giants are now on a nine-game losing streak.

Vikings running back Jordan Mason and center Ryan Kelly also left Sunday's game due to injury.