The Philadelphia Eagles will begin the playoffs against the San Francisco 49ers in the wild-card round next weekend at Lincoln Financial Field. 

The Birds (No. 3 seed) had a chance to earn the No. 2 seed with a win, but lost to the Washington Commanders in the regular season finale. 

Here's what you need to know about the matchup vs. the 49ers and more.

Which day will the Eagles and 49ers play?

The Eagles and 49ers will kick off at 4:30 p.m. Sunday. The game will air on FOX.

Eagles and 49ers postseason history

The Eagles and 49ers have only met twice in postseason history, most recently in the NFC championship game in the 2022 season. 

The Eagles won that game, 31-7, before falling to the Kansas City Chiefs in Super Bowl LVII. In that game, the 49ers were decimated at quarterback as Brock Purdy and Josh Johnson suffered injuries. 

After Johnson exited, Purdy returned to the game in the third quarter, but he was unable to throw the football beyond a few yards. The injuries to San Francisco's quarterbacks led to the NFL approving a rule change that allows teams to play an emergency quarterback if the starter and backup are injured.

The Eagles are 1-1 vs. San Francisco all-time in the playoffs. Philadelphia's loss to the 49ers in the playoffs happened in the wild-card round in 1996.

The title game in the 2022 season between the Eagles and 49ers started a rivalry that boiled over into 2023.

In 2023, the 49ers traveled to Lincoln Financial Field in Week 13 and dominated the Eagles, 42-19. The loss started the infamous collapse for the Eagles to end the season as the Birds lost six of the final seven games, including the playoff exit vs. the Tampa Bay Buccaneers. 

The loss to the Niners in the 2023 season also featured Eagles security chief Dom DiSandro and then-49ers linebacker Dre Greenlaw being ejected from the game after a scuffle on the sideline.

The Eagles and 49ers haven't played each other since the 2023 season. 

How the Eagles and 49ers got here

The Eagles went 11-6 in the 2025 season and won the NFC East for the second consecutive year, which ended a 20-year stretch of the division not having a repeat winner.

The Niners had a chance to earn the No. 1 seed, but fell to the Seattle Seahawks Saturday night. The 49ers finished the year with a 12-5 record to earn the No. 6 seed.

Eagles-49ers injury report

While the Eagles didn't get the No. 2 seed, they rested most of their starters in hopes of getting healthier heading into the playoffs. 

All-Pro right tackle Lane Johnson hasn't played since Week 11 vs. the Detroit Lions, but he's reportedly expected to return for the playoffs.  

Eagles defensive tackle Jalen Carter likely wasn't going to play in the regular season finale, but he popped up on the injury report with a hip injury before Week 18. Linebacker Nakobe Dean has also missed the last two weeks with a hamstring injury.

The 49ers are dealing with several notable injuries heading into the playoffs. 

San Francisco is missing star linebacker Fred Warner, who suffered an ankle injury in Week 6, heading into the wild-card round. Niners head coach Kyle Shanahan told reporters that Warner is progressing but not expected to make a return until later in the playoffs if the team advances. 

To make matters worse, the Niners lost linebacker Tatum Bethune, who was filling in for Warner, to a season-ending groin injury over the weekend in the Week 18 loss to the Seattle Seahawks. The 49ers are already without top pass rusher Nick Bosa, who tore his ACL early in the season. 

On the offensive side of the ball for the Niners, Pro Bowl left tackle Trent Williams missed Week 18 with a hamstring injury, while wide receiver Ricky Pearsall didn't play due to right knee and ankle injuries. 

Shanahan told reporters Monday that Williams and Pearsall will be evaluated later in the week. 

NFC playoff picture

• No. 1 seed Seattle Seahawks (bye)
• No. 2 seed Chicago Bears vs. No. 7 seed Green Bay Packers on Saturday at 8 p.m. on Prime Video
• No. 3 seed Philadelphia Eagles vs. No. 6 seed San Francisco 49ers on Sunday at 4:30 p.m. on FOX
• No. 4 seed Carolina Panthers vs. No. 5 seed Los Angeles Rams on Saturday at 4:30 p.m. on FOX