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A new defensive coordinator, an infusion of youth and the return of Dre Greenlaw had San Francisco 49ers star linebacker Fred Warner raving about how much fun he was having anchoring one of the league's more surprising units this season before heading out on the bye.
The San Francisco 49ers are bringing back three-time Pro Bowl defensive tackle DeForest Buckner after acquiring their former first-round pick in a trade with Indianapolis.
The NFL, Apple Music and Roc Nation announced Monday night that Jay-Z will be the featured performer for the halftime festivities on Feb. 14 at SoFi Stadium in Inglewood, California.
Michael Penix Jr. threw three touchdown passes, Atlanta scored 13 points off four turnovers and the Falcons handed the San Francisco 49ers their first loss, 29-20.
Brock Purdy threw a touchdown pass, Christian McCaffrey ran for two scores and the San Francisco 49ers held on to beat the Washington Commanders 23-17 for their sixth straight win to open the season.
The San Francisco 49ers were still basking in the glow of an exhilarating road win against division rival Seattle that extended their perfect start to the season when Christian McCaffrey offered a word of caution.
The youth movement on San Francisco's defense paid dividends when the 49ers needed it most in a tough game in Seattle.
Brock Purdy and the Niners (4-0) get a chance to reverse that trend when they visit the defending Super Bowl champion Seahawks (3-1) for the first time this season.
San Francisco 49ers fullback Kyle Juszczyk has won his appeal over the fines issued by the NFL for what it deemed an "offensive" celebration when he imitated drinking a beverage, which the league said looked like he was chugging a beer.
Brock Purdy threw two touchdown passes and Christian McCaffrey ran for a score to lead the undefeated San Francisco 49ers to a 24-14 victory over the Denver Broncos.
The 49ers are the first team in 12 years to allow no sacks through three games as Purdy's elusiveness and strong play from the offense line have frustrated the opposition.
The San Francisco 49ers keep losing key players to injuries and still keep winning, thanks in large part to the play of quarterback Brock Purdy.
Several Bay Area high schools have pulled the plug on their varsity football teams' seasons because of not having enough players to field a team.
The NFL fined San Francisco 49ers All-Pro fullback Kyle Juszczyk for what it deemed an "offensive" celebration similar to one he had been doing for several years with no issues.
A high school on California's Central Coast has abruptly canceled the remainder of the 2026 football season as officials launch an investigation into the program.
Christian McCaffrey became the fourth-fastest player in the Super Bowl era with 100 career touchdowns, Brock Purdy played a near-perfect game and the San Francisco 49ers overwhelmed the Miami Dolphins 35-13.
Jaron-Keawe Sagapolutele threw for a career-high 413 yards and three touchdowns in California's 49-7 victory over Wagner.
The Niners take on the team with the longest odds to win it all this season as the biggest favorites in Week 2 against the Miami Dolphins in their home opener on Sunday.
San Francisco 49ers rookie receiver De'Zhaun Stribling is expected to miss at least two months after undergoing surgery on his injured left ankle.
Jaron-Keawe Sagapolutele threw for two touchdowns, and Kingston Lopa made three interceptions as California beat Syracuse 21-18 in an Atlantic Coast Conference opener for both teams.
Mike Evans, Demarcus Robinson and Deebo Samuel caught touchdown passes from Brock Purdy, and the San Francisco 49ers routed the Los Angeles Rams 27-7 in the first NFL regular-season game in Australia.
The longest road trip in NFL history has brought the San Francisco 49ers and the Los Angeles Rams to Australia's sports capital for a season opener in front of more than 100,000 football-hungry fans packed into the Southern Hemisphere's largest stadium.
San Francisco 49ers coach Kyle Shanahan says defensive tackle Alfred Collins is out for the season after tearing his patellar tendon.
Aaron Donald won't play Week 1, delaying his return to the field after ending his retirement last month.
San Francisco 49ers star pass rusher Nick Bosa is set to play in the season opener against the Los Angeles Rams in his first game action since a tearing a knee ligament last September.
