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We only get so much time to live our lives. Some, more than others. But we all know there's an ending out there, someday. And being reminded of that reality - being confronted with it - can do amazing things.
For people whose cancer has stopped responding to standard therapy and are out of treatment options, a new trial is starting soon called the NCI-MATCH trial.
Jim Kelly is upbeat now that the Buffalo Bills Hall of Fame quarterback is back where he belongs.
The late County Councilwoman Barbara Daly Danko of Regent Square was a fighter for her causes, like opposing posting the motto 'In God We Trust' in council chambers because it was offensive to some.
Biologists are confirming the first case of cancer in a smallmouth bass caught in the Susquehanna River.
Legalizing medical marijuana -- the issue stirs emotion, as members of the state House Health and Judiciary Committees discovered at a hearing in Pittsburgh.
Angelina Jolie says she had her ovaries and fallopian tubes removed last week to ensure she has a long life with her husband and six children.
Treating brain tumors can be difficult, especially if they're rare or are in a particularly complicated part of the brain. Now, a combination of technologies is helping to map out a better treatment.
Meghan Lopresti's husband, Robert, was putting in the final core boards of their new laminate wood floor Sunday night when her dad called and told her to turn on "60 Minutes."
It was an unforgettable day for a Pittsburgh veteran.
Two basketball teams battled it out on the court Wednesday night, but the focus wasn't on the game. The players and fans were doing something special for a 2-year-old boy who is battling cancer.
At just 8-years-old, Nevaeh Griffin had the chance to experience prom.
Last year, Lisa Elaine Gallagher succumbed to brain cancer. Before she passed, the last thing she gave her 14-year-old son, Jack, was a pair of shoes endorsed by his favorite baseball player - L.A. Clippers basketball star Chris Paul.
A young boy from Bethel Park, who lost his battle with a rare form of brain cancer, was laid to rest this morning.
A tremendous outpouring of support from local law enforcement is expected at the funeral of a Bethel Park boy whose dream was to become a police officer.
A little boy, who captured the heart of the entire city during his battle with a rare disease, has died.
Wildlife biologists tracking a tumor-causing virus first diagnosed in eastern wild turkeys five years ago have found the virus is far more widespread — but less deadly — than expected.
A Monroeville teen used his bar mitzvah money to help out another teen fighting a brain tumor.
A major shortage of a critical cancer treatment drug led a local couple the KDKA'S Get Marty.
Two weeks after having surgery to remove a cancerous tumor from his thyroid, Olli Maatta will return to the lineup tonight.
State police say a western Pennsylvania man who befriended a woman at a harness racing track two years ago has since conned her out of $15,000 by pretending he had cancer.
A Leechburg woman fighting two battles reached out to KDKA-TV and Get Marty.
Mark Taylor was only 38 years old when he was diagnosed with cancer.
Earth movers are busily clearing away the natural surface of a couple of ball fields in Mount Lebanon's municipal park.
Brandon Lowe hit a tiebreaking homer in the ninth inning, Bryan Reynolds went deep from both sides of the plate and the Pittsburgh Pirates rallied from an early four-run deficit to beat the Athletics 6-5.
Dennis Brown, Jr., 29, of Oakdale, is facing charges in connection with the dirt bike chase last month.
The state House passed a bill that would make what's known as "gas station heroin" illegal in Pennsylvania.
A 2-year-old boy in Defiance County, Ohio, died in an accidental shooting, authorities said.
The Mountaineers ended the Trojans' first College World Series appearance with a 12-0 victory on Tuesday.
Kurt John Roy was one of the 12 people killed when a skydiving plane crashed in Missouri on Sunday.
Five tornadoes touched down across parts of eastern Ohio and northwestern Pennsylvania following Sunday's severe weather.
Changes will be coming to "skill games" in Pennsylvania after the state Supreme Court ruled the games are essentially slot machines.
Brandon Lowe hit a tiebreaking homer in the ninth inning, Bryan Reynolds went deep from both sides of the plate and the Pittsburgh Pirates rallied from an early four-run deficit to beat the Athletics 6-5.
Dennis Brown, Jr., 29, of Oakdale, is facing charges in connection with the dirt bike chase last month.
The state House passed a bill that would make what's known as "gas station heroin" illegal in Pennsylvania.
Changes will be coming to "skill games" in Pennsylvania after the state Supreme Court ruled the games are essentially slot machines.
The FBI said it disrupted an attempt to attack Sunday's UFC America 250 event at the White House, with court records detailing an alleged plot to use small drones carrying explosives.
The U.S. and Iran are expected to meet for a signing ceremony on Friday, June 19, in Switzerland, Pakistan's prime minister said.
The UFC hosted a fight series on the White House South Lawn Sunday night.
A Pennsylvania state lawmaker is proposing giving taxpayers $250 to celebrate America's birthday.
Buc-ee's plans to open another store in Ohio, bringing its gas station, convenience store and smiling buck-toothed beaver mascot closer to the Pennsylvania stateline.
A James Beard Award-nominated bar is coming back to Pittsburgh.
What if what's sitting in your jewelry drawer is worth more than you think?
The price of electricity in Pennsylvania is going up next month.
Here’s how you can make a vintage fireworks rocket centerpiece in just four minutes!
A birthday only comes around once a year, but a 250th birthday? That’s a once-in-a-generation celebration! Party-planning expert Shari Zatman takes us through the years to help you plan a timeless and patriotic party!
Antiques appraiser Dr. Lori is examining more of your family heirlooms and treasures. This week, Dr. Lori brings us "kitchen stuff."
Pittsburgh’s Palm Palm restaurant is completely redefining its dining experience, and Daisy Jade is on the scene to show us how they are “swaying” to a different tune.
PTL hosts Heather Abraham and David Highfield discuss Pittsburgh culture, trending news and social media, food, sports, and more. Plus, Taste it Tuesday brings us dessert pizza from Cork and Crust.
Many families with children attending schools in the Catholic Diocese of Pittsburgh said they are trying to figure out the logic behind their upcoming tuition bills.
Pittsburgh's fire boat has been on the water for nearly a decade, but it hasn't seen much action.
A lawsuit has been filed over the smell neighbors say is coming from the Sherwin-Williams plant in Rochester.
Naida Reed contacted KDKA Investigates after she said Pittsburgh Water failed to follow through on what crews allegedly promised.
What if what's sitting in your jewelry drawer is worth more than you think?
Allegheny County health officials said babies who have died from sudden unexpected infant death have more than doubled since 2000.
Lone star ticks have been found in Franklin and Erie counties in Pennsylvania.
Pittsburgh, with its natural beauty and parks, can be a great place for people to put the phones down and enjoy life.
Doctors say it looks like it will be a bad season for tick-borne diseases.
Temperatures could reach into the 90s this week in Pittsburgh, and that impacts everything, including your sleep.
Brandon Lowe hit a tiebreaking homer in the ninth inning, Bryan Reynolds went deep from both sides of the plate and the Pittsburgh Pirates rallied from an early four-run deficit to beat the Athletics 6-5.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
The Mountaineers ended the Trojans' first College World Series appearance with a 12-0 victory on Tuesday.
West Virginia must win Tuesday's game, or they'll be eliminated from the College World Series.
Nick Kurtz hit two homers and drove in five runs, Jeff McNeil also went deep and knocked in four, and the Athletics beat the scuffling Pittsburgh Pirates 11-2.
Pittsburgh City Council has approved new legislation that would put new restrictions on vape shops.
Buc-ee's plans to open another store in Ohio, bringing its gas station, convenience store and smiling buck-toothed beaver mascot closer to the Pennsylvania stateline.
A James Beard Award-nominated bar is coming back to Pittsburgh.
A fractured majority of Republican justices sided with a sweeping challenge brought by local and county officials against Oak Run Solar.
The move by Republican Gov. Mike DeWine comes as tax breaks for energy-hungry AI data centers are increasingly playing a role in state budgets.
Luke Skywalker's lightsaber from the "Star Wars" sequel "The Empire Strikes Back" is expected to sell for at least $1 million at an upcoming auction.
Locals spent Saturday at the Carrie Blast Furnaces for a day of sampling dozens of local beers and cocktails.
The Clarks are a band that Pittsburghers hear and think of home.
The Pittsburgh Symphony Orchestra has extended the contract of music director Manfred Honeck through the 2032-2033 season.
The country group Little Big Town will perform at Citizens Live at the Wylie in October.
KDKA-TV's Rich Walsh and 93.7 The Fan's Andrew Fillipponi discuss the sports topics of the day.
People in Castle Shannon were without water for hours due to a water main break.
The state House passed a bill that would make what's known as "gas station heroin" illegal in Pennsylvania.
Stay on top of the weather in the Pittsburgh area with First Alert Meteorologist Ray Petelin's forecast.
A man from Pennsylvania was one of the 12 people killed when a skydiving plane crashed on Sunday in Missouri, authorities said.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
