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Researchers have discovered a new cell in our immune system that they say could one day be used to create a "one size fits all" treatment for cancer.
Authorities say a reputed drug deal turned into a botched robbery that ended with a man fatally shot and charges filed against several people.
The cost to pull the Port Authority bus out of the massive sinkhole that opened in downtown Pittsburgh last October has been calculated at more than $88,000.
A former cocktail waitress at a Pennsylvania casino has been sentenced for her role in a $420,000 slot machine scam.
Greensburg Police are trying to identify a vehicle connected to a home burglary they say took place in broad daylight.
A man is facing attempted homicide and aggravated assault charges after firing a gun inside a home in Greene County.
The U.S. has its first case of a new virus that was found only last month in China, and health officials say they expect to see more around the world in the coming days.
The Pittsburgh Police K-9 Unit is mourning the loss of K-9 Sonic.
Iconic duo Hall & Oates are bringing their 2020 tour to Pittsburgh this summer.
Police in Armstrong County have filed charges against a man accused of threatening officers who arrested him during a bar fight.
Nickelback is once again hitting the road and they're bringing their just-announced tour to S&T Bank Music Park.
Even with the current cold spell, this month has been plenty warm with an average daily temperature of 37.5 degrees.
A 104-year-old US Marine Corps veteran who served in World War II is asking people to send him cards for Valentine's Day.
Police have charged a Wilkinsburg woman with a long list of felony counts after a fight over a parking space led to another woman being run down and pinned between two cars.
A man is in critical condition after they were shot inside a Stowe Township apartment Saturday afternoon.
Sheriff's deputies arrested a woman accused of trying to pass drugs off to an inmate at a court hearing.
The Washington County Board of Elections is spending tax dollars to fight a lawsuit against them over their decision not to count mail-in votes with errors on the return envelopes, and not allow people to correct them.
Murrysville and Homewood will open their pickleball courts this week.
Clarence Newson III was charged with DUI and other charges after slamming into a car on Friday night in West Mifflin.
United Airlines Flight 93 crashed near Shanksville, Pennsylvania, during the terrorist attacks of Sept. 11, 2001.
The Flight 93 Memorial will mark 25 years since Sept. 11, 2001, with a day of observance and ceremonies on Friday.
Brittany Ritter, a woman missing for more than one week from Ohio, was found dead on top of a train car in Indiana, authorities said.
Some scattered rain will linger throughout the weekend in the Pittsburgh area.
Kickoff is set for 7 p.m. at the U.S. Steel Community Field at Hazelwood Green.
Sen. John Fetterman's surprise video introducing Sen. Dave McCormick at the Republican Party's midterm convention sparked a strong reaction from Democrats. KDKA political analyst Jon Delano breaks it down.
Sen. John Fetterman's surprise video at the Republican Party's midterm convention sparked a strong reaction from Democrats.
Democratic Sen. John Fetterman appeared in a surprise video at the Republican Party's midterm convention on Wednesday, as he becomes increasingly isolated from his own party.
A Pennsylvania man is facing charges after police said he called Gov. Josh Shapiro's office and threatened to "destroy the Commonwealth."
The Trump administration moved Tuesday to ban imports of Canadian motorcycles, some dairy products and most types of alcohol starting later this month, intensifying the trade war between the two countries.
It seems like each week we get a new story or warning about a scam over the phone or on the internet. Here's how you can avoid them.
With proposed 50% tariffs on the table, the cost of new and used cars could increase by thousands in the near future.
A new report tries to calculate how much Pennsylvanians need to earn to live what's considered a comfortable lifestyle.
The store is expected to open sometime next year.
Buffalo Township police are warning about scammers after investigating several cases where residents have fallen victim.
Get your tickets now for the PTL Turkey Fund Kickoff Show happening at the Pittsburgh Playhouse on Sept. 18!
The Original Pittsburgh Taco Festival is back with over 25 food trucks and authentic Latin music. It takes place Saturday, Sept. 12, at The Stacks at 3 Crossings in the Strip District.
Daisy checks out Gameway, the new video gaming lounge at Pittsburgh International Airport!
Leechburg Pizza Company is the latest pizza place featured on PTL Pizza Friday!
The Pittsburgh County Fair will take place Saturday, Sept. 12, at Allegheny Commons Park West. It's a celebration of urban agriculture and all things handmade, homemade, and delicious in Pittsburgh.
The Steel City Youth Football League announced disciplinary action following video that captured an on-field brawl.
Misdemeanor and summary charges have been filed against the coaches involved in a youth football brawl in Pittsburgh.
Police departments all around the country say surveillance technologies like cameras, drones, and license plate readers have proved invaluable in tracking and arresting violent criminals.
Video shows youth football coaches from Carlynton and Keystone Oaks fighting on the field during a game over the weekend.
Police public safety services are being questioned in Forward Township.
A Pittsburgh-area hospital is seeing a concerning uptick in withdrawals from what many describe as "gas station heroin."
Mental health days aren't just for adults; oftentimes, children need them, too, so here's what parents need to be on the lookout for.
Getting zapped by lightning is an enormous danger, and with an uptick in strikes in the Pittsburgh area, here's what you need to know.
A Pittsburgh-area mother is sharing her story after she says her daughter was exposed to measles at UPMC Children's Hospital.
Pennsylvania health officials said an out-of-state person tested positive for measles and may have exposed others at a Pennsylvania Turnpike service plaza in Westmoreland County.
Kickoff is set for 7 p.m. at the U.S. Steel Community Field at Hazelwood Green.
Jared Jones pitched seven innings of one-hit ball, Oneil Cruz added a solo home run and the Pittsburgh Pirates beat the Chicago White Sox 2-0 on Thursday night to complete a three-game series sweep.
Phil, the two-time champion, and Amanda, the Penguins' Manager of Minor League Operations, are both heading to the Hall of Fame.
The grant funding comes after a gunshot was fired near the district's high school football stadium last month.
Cameron Heyward is criticizing the franchise tag, calling it "stupid.".
Many small businesses are still feeling the impact of last week's severe weather.
Pittsburgh leaders and their partners are making a concerted effort to revitalize a North Side business district.
A federally funded Ohio manufacturing program faces potential shutdown after a new audit by the U.S. Department of Commerce's Office of Inspector General.
Gas station giant Buc-ee's has sparked a backlash in Ohio over one of its frequent trademark infringement lawsuits.
The international fashion retailer Zara will open a location in Ross Park Mall in 2028, as the mall continues to thrive.
Local legend Donnie Iris will headline an early show at Pittsburgh's newest music venue, Citizens Live at The Wylie.
Dolly Parton died in Nashville on Aug. 25 at the age of 80 — a shock to fans around the world who weren't aware of her illness.
A show coming to The Palace Theatre in Greensburg looks to pay tribute to Dolly Parton.
Tim Curry was known for his iconic performances in cult classics like "The Rocky Horror Picture Show" and the original screen adaptation of Stephen King's "It."
Pittsburghers are remembering Dolly Parton as "one of a kind" following her death on Tuesday.
Get your tickets now for the PTL Turkey Fund Kickoff Show happening at the Pittsburgh Playhouse on Sept. 18!
The Original Pittsburgh Taco Festival is back with over 25 food trucks and authentic Latin music. It takes place Saturday, Sept. 12, at The Stacks at 3 Crossings in the Strip District.
Daisy checks out Gameway, the new video gaming lounge at Pittsburgh International Airport!
Leechburg Pizza Company is the latest pizza place featured on PTL Pizza Friday!
The Pittsburgh County Fair will take place Saturday, Sept. 12, at Allegheny Commons Park West. It's a celebration of urban agriculture and all things handmade, homemade, and delicious in Pittsburgh.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
