The World Health Organization has declared the spread of the Zika virus to be a global emergency. America has yet to see a major outbreak and isn't considered to be at high risk, but some states have started to battle the disease. Meanwhile, authorities in South America fear the worst isn't over yet.
Brazil is the epicenter of the Zika outbreak, which has reportedly infected at least 1.5 million people there. Brazil also was the first to report a surge in newborns with microcephaly that parallels the outbreak. At least 4,100 infants reportedly have been born with that condition, compared with fewer than 150 in 2014.
Brazil: Concern around the Olympics
Brazil's National Biosafety Committee has mobilized armed forces and approved the release of insecticides and genetically modified mosquitoes to combat the virus, but fear is still high, particularly around the Olympic games slated for Rio in August; the U.S. Olympic Committee has said it will discuss potential risk with employees and sports leaders.
Researchers in Colombia have recently identified their first cases of birth defects believed to be linked to Zika - a finding that could signal a wave of related birth defects in that country.
According to U.S. Centers for Disease Control and Prevention, hundreds of thousands of people in the U.S. territory of Puerto Rico could become infected with the Zika virus in the coming months. CDC Director Tom Frieden traveled to the U.S. territory in March to monitor the situation, citing more than 100 cases already on the island.
"Puerto Rico is on the frontline of the battle against Zika," said Frieden. "And it's an uphill battle."
Hawaii is already fighting a troubling outbreak of dengue fever, a disease carried by the same mosquitoes that transmit Zika. And the battle may worsen: Hawaii has strong anti-pesticide sentiment and tropical conditions, and is suffering from under-staffing in its Department of Health.
At last count, the state has logged five Zika cases, all travel-related.
The University of Texas Medical Branch in Galveston and a state public health lab in Austin are on the front lines of testing and studying the Zika virus.
According to the latest count, Texas has at least 19 confirmed Zika patients.
So far Texas' cases are travel-related, though at least one patient reportedly contracted the disease sexually from someone who was infected abroad. But mosquitoes that spread the virus can thrive here.
"It's only a matter of time before Zika virus is locally transmitted here by mosquitoes," Dr. John Hellerstedt, commissioner of the state health department, said recently in a statement.
Of all the U.S. states with confirmed cases of Zika virus, Florida has seen the most. At last count, the Sunshine State has faced at least 50 cases, though none have spread locally.
Florida: Pregnant women diagnosed
All of Florida's cases are believed to be travel-related, meaning that the sickness was contracted outside U.S. borders, according to that state's health department.
Among the confirmed cases: At least four pregnant women. Floridians have been urged to dump or cover anything on their property that holds standing water, all the better to fight mosquitoes and their virus-spreading bites.
Mexico has been listed by the European Center for Disease Prevention and Control as a country seeing "increasing or widespread transmission" of the Zika virus. At least 11 pregnant women have been diagnosed with Zika in that country, among more than 120 total cases.
American Samoa and U.S. Virgin Islands
The CDC has recorded at least one confirmed Zika patient in the U.S. Virgin Islands. That case was contracted locally. American Samoa, a U.S. territory in the Pacific, has seen at least 13 cases.
Both territories are under a CDC travel advisory urging Americans to use caution if visiting those spots and encouraging pregnant women to stay away.
Guatemala, El Salvador, Honduras, Panama, Nicaragua and Costa Rica all have been listed by the European Center for Disease Prevention and Control as suffering from "increasing or widespread transmission" of Zika.
Haiti and Dominican Republic
The two countries share an island that saw the first signs of outbreak in January. At least 10 cases of Zika have been diagnosed in the Dominican Republic.
Doctors have reported that at least two people suffering from a rare paralyzing condition on the Caribbean island of Martinique had evidence of Zika infection. Barbados, Martinique, Grenadines, St. Vincent and St. Martin are all under a CDC travel advisory.