A wicked witch appears to scream into space in the appropriately named from Witch Head nebula. This image was taken by NASA's Wide-Field Infrared Survey Explorer, or WISE.
According to the NASA web site, this image depicts baby stars being born in fluffy dust clouds, lit up by massive stars. Dust, heated by nearby stars, glows with infrared light, which was picked up by WISE's detectors.
The Witch Head nebula is in the Orion constellation, just off the hunter's knee.
WISE was put into hibernation in 2011 but was recently "awakened" to hunt for asteroids in a program called NEOWISE.