Paul Drinkwater/USA Network/NBCUPB via AP Images
Shirley MacLaine and brother Warren Beatty are pictured during the 36th Annual AFI Life Achievement Award tribute to Beatty, held at the Kodak Theater on June 12, 2008. The two are among the most accomplished of Hollywood sibling duos, yet never acted together in the same film.
AP Photo/Nousha Salimi
Actor Ben Affleck (an Oscar winner for writing "Good Will Hunting") and his brother Casey Affleck (a Best Supporting Actor Oscar nominee for "The Assassination of Jesse James by the Coward Robert Ford") arrive on the red carpet at the opening of the 5th Dubai International Film Festival in Dubai, United Arab Emirates, Thursday, Dec. 11, 2008.
AP
Lloyd Bridges poses with his sons Beau, left, and Jeff in Malibu, Calif., in this 1980 file photo. Lloyd's career spanned TV ("Sea Hunt") and films ("High Noon," "Airplane!"), and his sons followed in his footsteps, appearing together in "The Fabulous Baker Boys." Jeff Bridges won the Academy Award for "Crazy Heart."
AP
Olivia de Havilland (left) and Joan Fontaine grew up in Tokyo where their father worked as an attorney, but their parents divorced soon after they were born. They both attained star status during Hollywood's Golden Age, and both won Academy Awards (Olivia for "To Each His Own" and "The Heiress," and Joan for "Suspicion"). But they fought bitterly as youngsters, and their rivalry and estrangement has lasted to this day.
Jennifer Graylock
Maggie Gyllenhaal and Jake Gyllenhaal attend the 82nd Annual Academy Awards, held at the Kodak Theater in Hollywood, California, Sunday, March 7, 2010.
KEVIN WINTER
The Arquette Family boasts a host of thespians. From left, Alexis Arquette ("Here and Now"); Rosanna Arquette ("Desperately Seeking Susan"); Richmond Arquette ("Prison Break"); Patricia Arquette ("Medium"); and David Arquette ("Never Been Kissed"). They're pictured here arriving at the AFI Associates Sixth Annual Platinum Circle Award luncheon in Beverly Hills, Calif., Wednesday, May 11, 2006.
REED SAXON
From left: Zooey Deschanel ("(500) Days of Summer") and Emily Deschanel ("Bones") are the daughters of actress Mary Jo Deschanel ("The Right Stuff") and cinematographer Caleb Deschanel. They're pictured arriving at the 2006 Independent Spirit Awards Saturday, March 4, 2006, in Santa Monica, Calif.
Actress Jane Fonda gestures with a finger at her brother, Peter Fonda, as they arrive to attend the Paris premiere of "The Wild Angels" on Jan. 31, 1967. The children of actor Henry Fonda are also pictured at right, arriving for the Film Society of Lincoln Center tribute in her honor, Monday, May 7, 2001 in New York.
AP/Warner Brothers
Sisters Margaux Hemingway (left) and Mariel Hemingway, grandchildren of novelist Ernest Hemingway, appeared together in the 1976 thriller "Lipstick."
AP Photo/Evan Agostini
Actress Anjelica Huston ("The Grifters") arrives with her half-brother Danny Huston ("Robin Hood") at the Vanity Fair Oscar party on Sunday, Feb. 22, 2009, in West Hollywood, Calif. Their dad John Huston is the only director to win Oscars for directing his own daughter (for "Prizzi's Honor") AND his own father (Walter Huston, for "The Treasure of the Sierra Madre").
AP Photo/Tammie Arroyo
Michael Madsen ("Thelma and Louise") and sister Virginia Madsen ("Sideways") arrive for the premiere of "Kill Bill Vol. 2" at The Arclight Cinerama Dome in Los Angeles, Thursday, April 8, 2004.
AP
In this 1967 file photo at left, sisters Vanessa and Lynn Redgrave attend the post-Oscar party in Los Angeles, each having been nominated for Best Actress: Vanessa for "Morgan!," and Lynn for "Georgy Girl." Right, the daughters of actor Michael Redgrave pose at the Tony Awards in New York on June 8, 2003, when Vanessa won Best Actress in a Play for a revival of "Long Day's Journey into Night."
United Artists
Walter Hill's 1980 outlaw Western "The Long Riders" made good use of fraternal casting, with David Carradine and his half-brothers Keith and Robert playing the Younger Brothers; Nicholas Guest and Christopher Guest playing Bob and Charlie Ford; Dennis Quaid and Randy Quaid as the Miller Boys; and Stacey and James Keach as Frank and Jesse James.
AP Photo/Rhonda Birndorf
Charlie Sheen (left, born Carlos Estevez) poses with his father, actor Martin Sheen and brother, Emilio Estevez, after receiving his star on the Hollywood Walk of Fame in Los Angeles, Calif., on Sept. 23, 1994. The brothers acted together in the 1990 comedy "Men at Work."
AP Photo/Chris Polk
The Wilson brothers From left, Andrew, Owen and Luke arrive at the Four Seasons Hotel in Maui, Hawaii, Thursday, June 16, 2005 during the Maui Film Festival.