McEwen was voted one of the most trusted people in America and was a fixture on CBS in the mornings from 1987 until 2002. His wit and warmth made him a welcome guest in millions of homes. The stroke almost took all that away.
"I remember I looked up and saw my father, my brother, both my sisters," he told his longtime friend and colleague, Early Show co-anchor Harry Smith. "That's when I knew."
Neurosurgeon Dr. Max Medary of the Sand Lake Hospital in Orlando, Fla. treated McEwen. Medary said he was very close to death.
"The diagnosis of basilar artery thrombosis is a very, very poor prognosis," Medary said.
For four days, McEwen hung near death. The blood clot that caused the stroke had blocked oxygen from his brain. If and when he recovered, he would be starting over.
"Boy, I was in bed, I couldn't walk. I could barely talk. I talked slower and higher," he told Smith.
First, he was confined to a wheelchair, then he moved to a walker. He struggled to regain the use of his right hand. Most devastating of all though was the impact on his voice and speech. From his days as a standup comedian, to radio, to TV, McEwen had always been glib.
At first, McEwen had a difficult time learning how to speak properly. He struggled with "K" sounds and vowels. He measured his progress with simple milestones.
"Boy, the first time I showered, the first time I drove, it was great," he said. "I work harder now than I did when I had a job. It's been speech, it's been my balance, it's been to think right, to think OK."
Despite his difficult journey, McEwen said he's not depressed because "all I've seen is improvement."
"I walk. I talk. I think. I drive. I wash myself. I shave," he said. "I brush my teeth. I make the bed. I do everything."
He attributes much of his progress to his wife, Denise, who, he says, has been his support and inspiration.
"She married me, she thought I would be a certain way," McEwan said. "For better or for worse. I never knew that I would have this, and she's great. She's lived up to her end of the bargain. She has."
But Denise McEwen has faith in her husband's recovery.
"We were watching 'Jeopardy.' I knew Mark was going to be all right because every single question, he got right," she told Smith.
McEwen's station, WKMG in Orlando, Fla., has kept his position open, believing that, with enough hard work, he'll be back on the air. McEwen has enjoyed a brilliant career and it remains a proud part of his life. But, his stroke also shed some light on just how fortunate he still is.
"People come in here and say, 'Gee, you've had a great life,'" he said. "I say, 'I have a great life!'"
McEwen now says he know what really matters in life.
"All this, is an illusion," he said. "The house, the fame the fortune, what we do. What is important is family and friends. That's what I know."
Today, he has a new mission: He says he wants to do for strokes what Lance Armstrong did for cancer.
"I want people to know that this doesn't discriminate, but I want people also to know that you can come back," he said. "I'm writing a book about my experiences during this stroke and coming back. And I just want people to know that it can happen. It happened to me."