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The opioid epidemic has doctors and patients rethinking painkillers. At UCHealth, there is a concerted effort to educate people about opioids.
The United State Air Force Thunderbirds practiced their performance on Tuesday in preparation for the Air Force Academy's graduation on Thursday.
A car crashed into a restaurant in Littleton on Tuesday. Police believe the driver accidentally hit the gas instead of the brakes.
A bill increasing the number of locations where Colorado residents who are in the country illegally can obtain driver's licenses has become law.
Tate Schrock lives on a farm in Anton, Colorado, and uses the work there to inspire his inventions.
Longtime CBS newsman Scott Pelley discussed his new book and why he wanted to write about those who inspire him.
A bill increasing the number of locations where Colorado residents who are in the country illegally can obtain driver's licenses has become law.
Gov. Jared Polis stopped by the Second Chance Center in Aurora on Tuesday to sign a bill which will give former inmates a second chance.
Denver Mayor Michael Hancock's deputy chief of staff emailed supporters over the weekend with a dire warning, according to a copy of the email obtained by CBS4.
The West Metro Fire Protection District has reached an agreement to pay 70 retired firefighters and their families $1.2 million to settle a class action lawsuit over retiree health benefits.
The Cheyenne Mountain Zoo shared video of mom Charlotte Greenie and her new baby boy sharing "kisses" on Tuesday.
The cubs are just six weeks old and were orphaned when their mother was killed.
People who live in Denver can drop off their broken branches for free. Monday night's storm left some damaged trees and broken branches around the city.
Wildlife officials in western Colorado are searching for a black bear that bit a woman's leg as she hiked on a trail near Aspen.
The owner of Mile High Comics says someone broke into the store in Denver on Sunday and stole 14 comics worth more than $42,000.
CBS News Colorado Political Specialist Shaun Boyd spoke with members of legislation after lawmakers approved one of Colorado's biggest investments in child welfare in years.
NBA critics believe Jokic had a "strong overall campaign and stellar finish" out of the other league MVP candidates in OKC's Shai Gilgeous-Alexander, Maverick's Luka Doncic, Buck's Giannis Antetokounmpo, and Celtics' Jayson Tatum.
On Feb. 14, investigators believe that Antonio Vasquez and Jason Trujillo, Jr. shot and killed Dacien Salazar.
Investigators said genetic genealogy DNA helped solve Maria Honzell's murder that happened nearly 50 years ago.
Investigators searched for a suspect and suspect vehicle involved in the incident at Frontier Valley Elementary School.
A teenage girl was shot and killed in a weekend shooting in western Aurora. Aurora police said it happened late Saturday night and a suspect is in custody.
A strong ridge of high pressure is driving temperatures in Colorado to climb well above normal for early August prompting First Alert Weather Days on Sunday and Monday.
Denver's Mile High Flea Market transformed into an interactive art space Saturday as "Canvas and Culture" brought together local artists, families, and creators for a day of hands-on activities.
The Denver Police Department is investigating a stabbing that left multiple people injured on Saturday.
On Saturday morning, lawmakers and residents gathered in Aurora for an update on the city's water usage amid the drought.
Denver's Mile High Flea Market turned into an interactive art space on Saturday.
A family disturbance took place near 52nd Avenue and Sherman Street, according to Denver police. A suspect is in custody.
Watch meteorologist Callie Zanandrie's forecast.
A bear was spotted raiding trash cans in Denver's Cherry Creek Neighborhood early Saturday morning.
Denver's Mile High Flea Market turned into an interactive art space on Saturday.
FIFA chief Gianni Infantino had proposed creating a $20 billion company to run the World Cup with private investors but drew backlash that grew every day since Tuesday's announcement.
FIFA is shelving a controversial plan that would have allowed for billions of dollars in private commercial investment in the World Cup after the proposal was met with fierce opposition from its member nations.
The pressure is rising on FIFA President Gianni Infantino to ditch a $20 billion privatization plan, but soccer's governing body is doubling down and criticizing the media.
Prior to the start of the Colorado Buffaloes early August football practices in Colorado Springs, head coach Deion Sanders visited his son at Cleveland Browns training camp.
The logo being used by a high school in Aurora is now being called into question.
Democratic Sen. Mark Kelly also voiced concerns about the Pentagon's funding requests, calling the approach "irresponsible — and now they want a blank check."
Vincent Pastore played Salvatore "Big Pussy" Bonpensiero on all six seasons of "The Sopranos," which aired from 1999 to 2007.
FIFA chief Gianni Infantino had proposed creating a $20 billion company to run the World Cup with private investors but drew backlash that grew every day since Tuesday's announcement.
Savannah Guthrie said she and her family have been "in agony and despair ever since" her mother Nancy's disappearance in February.
Investigators are probing whether Iranian hackers are behind this week's malicious cyber activity against water systems in Minnesota. If they are found to be the culprits, it would not be the first time.
Democratic Sen. Mark Kelly also voiced concerns about the Pentagon's funding requests, calling the approach "irresponsible — and now they want a blank check."
Colorado Republican Gubernatorial Nominee Victor Marx has selected retired Marine Col. George Markert as his running mate for Lt. Gov.
Investigators are probing whether Iranian hackers are behind this week's malicious cyber activity against water systems in Minnesota. If they are found to be the culprits, it would not be the first time.
The U.S. Department of the Interior has issued its plan for how to manage water on the Colorado River.
A new law will require legal guardians to sign off before a minor can obtain a motorcycle permit. Supporters hope it will improve safety as e-motorcycles become increasingly popular.
The Department of Justice in June issued a legal opinion saying states aren't required to provide services that help people with disabilities remain in their homes.
If confirmed by the full Senate, Dr. Erica Schwartz would become the 22nd director of the Atlanta-based Centers for Disease Control and Prevention.
Telehealth platform disclosed users' "most private" health info and locked consumers into subscriptions, regulators allege.
Congress appropriated $345 million for the Agency for Healthcare Research and Quality for the 2026 fiscal year, but the agency has spent less than $15 million on grants.
Carly Simon, the singer known for 1970s hits like "You're So Vain," announced she has Parkinson's disease and also was treated for basal cell carcinoma.
A growing tech company is betting on Denver as it expands its North American footprint, saying the city's affordable office market, educated workforce and central location made it the clear choice.
The families of four children who died by suicide allege that using social media led to depression, anxiety and other mental health problems.
Chinese-made electric bedding poses "risk of serious injury or death," according to U.S. product safety regulators.
A lawsuit alleges that a drive storing a $45 million spy film starring Nicolas Cage was "stolen right off a Netflix desk."
A source close to Joshua Kushner's firm tells CBS News there's no politics behind FIFA's bid to draw private investment, but Europe's soccer powerhouses are crying foul.
A series of sports photos have become treasured memories for a grieving community.
Nearly three out of every four written comments submitted to the Colorado Department of Transportation during the early public review of its proposed Bus Rapid Transit project on Colorado Boulevard oppose the idea.
Insurance can be a hassle for anyone. For one Coloradan, that hassle has been magnified all because of her name.
A man who stopped to help victims of a devastating motorcycle crash instead found himself handcuffed, jailed and accused of driving under the influence -- despite repeatedly asking officers to administer a breath test that he believed would prove his innocence.
For Billy Hailey, his release was a day he had been waiting for and working toward for 20 years. Now, he is unexpectedly back in custody after the state says it miscalculated the date.