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This time it was the passing game that set up the run and led to a 45-3 win over the visiting Buffalo Bills. Alex Smith finished with over 300 yards passing while the defense played another impressive game. With momentum on their side, the 49ers will take on the New York Giants next week in the biggest game of the year for San Francisco.
Aside from the ban on "extracurricular activity" after kickoff, here are nine other things you need to keep in mind if you plan to eat, drink and celebrate before 49ers games at The Stick.
The 49ers injury report continues to shrink while the Buffalo Bills have a few lineman who are out for Sunday's game. For a team that relies a lot on their run, the Bills will hope that the back ups and create holes in the running game for their backs. For the 49ers Brandon Jacobs looks to make his 49er debut.
The Buffalo Bills head into Sunday's game against the 49ers as underdogs. Buffalo had a rough end to last year and has had an up-and-down start to this year. For a team that has had problems with turnovers and no real way to move the ball other then on the ground, the Bills will have quite a challenge to beat San Francisco.
The news this week around 49er camp is the naming of Patrick WIllis as NFC Defensive Player of the Week. However, he has had to share the headlines with Brandon Jacobs, who has announced that he is ready to get back on the field.
The 49ers will have to remain humble as they try to improve on the success that they had last year. To avoid a similar let down to the performance they had against Minnesota Vikings, the team will have to stay humble and motivated. To help in their motivation is their new weight room, so the Bills will face a team that certainly hit the weights in preparation for them.
Colin Keapernick made his presence felt in last week's win over the New York Jets. He size and speed put him in the same conversation with Cam Newton and Tim Tebow, but he is still far from earning a starting role in this league. He is on the right team with the right coach and will have a chance to show what he is made of eventually.
San Francisco responded after last weeks last with a 34-0 win over the New York Jets. The team did not play great, but dominated the Jets the whole day and showed that they are the team with a back up quarterback who can make a difference.
Here's some information that can make the Candlestick parking experience almost as effortless as a Steve Young-to-Jerry Rice pass.
The injury report for the 49ers and Jets had the usual precautionary listings, but the name that stood out is Darrelle Revis. The Jet star is out of the season and both teams will attack the game differently with him out of the line up.
The Valkyries are 11-4 in home games. Golden State leads the WNBA in team defense, allowing 76.9 points while holding opponents to 42.5% shooting.
San Francisco 49ers receiver Ricky Pearsall will have season-ending surgery on his injured right knee in the latest setback for the 2024 first-round pick.
Dillon Dingler hit a grand slam in Detroit's seven-run eighth inning and the Tigers opened their longest trip of the season with a 13-1 win over the Athletics.
Family, friends and volunteers spent Saturday searching Stockton neighborhoods for 23-year-old Obonjai "Bonj" Skaggs, a missing Navy veteran who was last seen nearly two weeks ago.
Firefighters were called around 1:30 a.m. for a potential structure fire near Hatch Road and Herndon Avenue.
Along with high temperatures, air quality will also be a concern due to wildfire smoke from the Woodside Fire burning on the Sonoma County coast.
The Valkyries are 11-4 in home games. Golden State leads the WNBA in team defense, allowing 76.9 points while holding opponents to 42.5% shooting.
Records reveal California twice missed deadlines to buy the trains at the center of a federal funding fight — then quietly dropped its lawsuit weeks after missing its new deadline.
As a heat dome pushed temperatures higher across much of the West, residents around Sacramento found creative and refreshing ways to stay cool.
Police said they learned he was at his apartment and tried to arrest him, but he barricaded himself inside the home. The standoff went on until about 4:45 a.m., when officers forcibly entered the home and arrested him.
Trying to beat the heat at the California State Fair has been a Sacramento summertime tradition, but now it's coming to an end as the state fair is moving to the fall next year.
A Sacramento County-appointed fiscal advisor has blocked a recently approved agreement between the Sacramento City Unified School District and its teachers' union, saying the deal would not provide a sustainable solution to the district's ongoing financial crisis.
A vehicle crashed into the side of the Flame Club in Midtown Sacramento on Friday afternoon, officials said.
California Gov. Gavin Newsom's office has released tax returns showing he and his wife made between $1.7 million and $2 million annually from 2022 through 2024.
California's minimum wage is set to increase again in 2027 as part of the state's annual inflation adjustment.
A man clung to the steep side of a Fresno canal while holding onto his dog Tuesday after jumping into the water to rescue the animal.
A dramatic rescue at Seabright State Beach in Santa Cruz is highlighting the dangers of powerful surf and rip currents along the California coast this week.
Firefighters have fully contained the Dove Fire in Tuolumne County, bringing an end to a weeklong firefight that prompted mandatory evacuations near Sonora and Jamestown and led to the arrest of a man accused of starting the blaze.
The Valkyries are 11-4 in home games. Golden State leads the WNBA in team defense, allowing 76.9 points while holding opponents to 42.5% shooting.
San Francisco 49ers receiver Ricky Pearsall will have season-ending surgery on his injured right knee in the latest setback for the 2024 first-round pick.
Dillon Dingler hit a grand slam in Detroit's seven-run eighth inning and the Tigers opened their longest trip of the season with a 13-1 win over the Athletics.
FIFA is shelving a controversial plan that would have allowed for billions of dollars in private commercial investment in the World Cup after the proposal was met with fierce opposition from its member nations.
Romo was arrested in Wisconsin last week, accused of operating a vehicle while intoxicated.
Records reveal California twice missed deadlines to buy the trains at the center of a federal funding fight — then quietly dropped its lawsuit weeks after missing its new deadline.
California Gov. Gavin Newsom's office has released tax returns showing he and his wife made between $1.7 million and $2 million annually from 2022 through 2024.
Dr. Anthony Fauci appeared before the Senate to testify on the origins of the COVID-19 pandemic but invoked his Fifth Amendment rights in answering all questions.
Former FBI Director James Comey argued that criminal charges stemming from an Instagram post should be dropped because his speech is protected by the First Amendment.
A federal appeals court has upheld a judge's ruling that halted President Trump's efforts to create a federal voter list and limit who can receive a mail ballot.
CBS News Sacramento spoke with the head of UC Davis Children's Hospital about the rising cases and why measles specifically is the most infectious disease.
The case accuses OpenAI of practicing medicine without a license and failing to safeguard users seeking health advice.
A generic version of the allergy medication Zyrtec is under recall across the U.S. over cross-contamination concerns.
Here's how weight-loss drugs like Ozempic and Wegovy could reduce worker illness and save companies money.
Taylor Farms said none of its branded salads or kits contain the iceberg lettuce associated with the outbreak.
During the program's first year, it will be offered at about 65 to 75 hospitals that handle about a quarter of births in the state and largely serve low-income patients, Newsom's office said.
Fresh off their undefeated season and conference championship win, the women on the team are speaking out for the first time.
Finding the perfect dress isn't easy, but now, selling them could become a lot more challenging.
This weekend, Placer County is hosting its annual Sip Into Spring event, offering free or discounted tastings at more than 20 wineries along what's known as the Placer Wine Trail.
From fruits and veggies to car parts, economists project that businesses will pass along the cost of the tariffs to customers.
President Trump and Gov. Gavin Newsom have made several different claims about California gas prices. Here's what we found.
This year-long investigation provides an unprecedented look at California's one-party supermajority legislature through the eyes of grieving parents who discover how California lawmakers kill popular bills by not voting.
This year-long investigation by CBS News California investigative correspondent Julie Watts examines the many components of California's new tougher-on-crime law.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
The California Highway Patrol captain accused of workers' compensation fraud was the commander in charge of the fatal Mahaney Park shootout in Roseville, three officers who worked under him at the time of the shootout said.
CBS13 and the Call Kurtis consumer investigative team devised an idea on how to lower what consumers owe on their credit cards -- and it begins with a simple phone call.
No one wants to think about death. However, it's important to plan on what happens to your digital assets after you die.
After spending $18,000 on waterproof laminate floors, a Natomas couple spotted damage after the first cleaning.
More than a year after Hai Pham canceled the trial membership, he kept getting charged every month for it.
A Natomas mother demanded that her daughter be exhumed and cremated after a Sacramento cemetery moved her grave without telling the family.
All evacuation orders have been lifted for a fast-moving wildfire that sparked near the Nevada and Yuba county line Wednesday afternoon.
Firefighters stopped the forward progress of a vegetation fire that forced evacuations Sunday afternoon in the Pilot Hill area of El Dorado County.
Nothing but rubble remains of the McCombs home that was destroyed by the Kearny Fire. All their kids' toys, a wedding dress, memories and everything that meant something to them are completely gone.
All evacuation orders were lifted for a grass fire in rural Nevada County, west of Penn Valley, on Tuesday.
The Van Fire was reported Wednesday northeast of White Rock Road in Cathey's Valley, and north of Eastman Lake. The cause of the fire remains under investigation.
Their message is simple: keep showing up, keep moving and keep your heart open, because sometimes, the person who changes your life is living right across the street.
A Sacramento County dog picked up thousands of miles from home after he went missing five years ago was reunited with his family on Wednesday.
What started as a suspicious circumstances call for Rancho Cordova police ended with a newborn surprise.
A once-empty lot behind Church of the Cross in north Modesto now hosts a thriving community garden with more than 140 plots and growers from across the globe.
A Sacramento-area middle school history and English teacher is in the running to win big as America's Favorite Teacher, a title her students think she is more than worthy of being awarded.
Conor McGill reports.
Here is a look at your next seven days of weather!
Family, friends and volunteers spent Saturday searching Stockton neighborhoods for 23-year-old Obonjai "Bonj" Skaggs, a missing Navy veteran who was last seen nearly two weeks ago.
Trying to beat the heat at the California State Fair has been a Sacramento summertime tradition, but now it's coming to an end as the state fair is moving to the fall next year.
A vehicle crashed into the side of the Flame Club in Midtown Sacramento on Friday afternoon, officials said.