CBS announced Monday that his guests will include Bill Murray, George Clooney, Steve Martin, Jerry Seinfeld, Robert Downey Jr., Will Ferrell, Tina Fey, Tom Hanks, Scarlett Johansson, Sarah Jessica Parker, Don Rickles, Julia Roberts, Ray Romano, Howard Stern, Oprah Winfrey, Martin Short, John Travolta, Michael J. Fox and Alec Baldwin.
And there will be others who haven't been announced yet.
Musical guests will include Elvis Costello, Dave Matthews Band, Mumford and Sons, Norah Jones, Amos Lee and Tracy Chapman.
Letterman hasn't specified who, if anyone, will join him for his final show after 33 years on late-night TV.
For more entertainment news from CBS Local, click here.
(TM and © Copyright 2015 CBS Radio Inc. and its relevant subsidiaries. CBS RADIO and EYE Logo TM and Copyright 2015 CBS Broadcasting Inc. Used under license. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. The Associated Press contributed to this report.)
for more features.