But four new colors are taking their places: jazzberry jam, mango tango, inchworm and wild blue yonder.
The changes were part of a competition to celebrate Crayola's 100th anniversary on Saturday, when the new colors will be introduced.
The company had picked five colors that it considered redundant or unattractive, but allowed one to be spared through an online vote. Burnt sienna received the most votes of the 60,000 cast and avoided retirement.
"It's a heart-wrenching process because we grew up with many of these sentimental favorites, too," said Stacy Gabrielle, a Crayola spokeswoman.
The only other time that Crayola retired colors was in 1990, when maize, lemon yellow, blue gray, raw umber, green blue, orange red, orange yellow and violet blue were "enshrined in the Crayola Hall of Fame."
Crayola has renamed colors three times since 1903: "Prussian blue" became "midnight blue" in 1958, "flesh" became "peach" in 1962, and "indian red" became chestnut in 1999.