Neil Patrick Harris spars with Hugh Jackman

(CBS) Neil Patrick Harris spared no one in his return for a second stint as host of the annual Tony Awards Sunday night in New York.

Among the targets of the "How I Met Your Mother" star's humor were Daniel Radcliffe, Brooke Shields, Angela Lansbury, Al Pacino, Bono and The Edge.

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Harris kicked off the awards show at New York's Beacon Theater with a song-and-dance number about how "the Tonys are not just for gays anymore." It involved Stephen Colbert, Brooke Shields, Bobby Cannavale and bunch of bleeps.

He also engaged in a Tony host face off with actor Hugh Jackman, who has hosted previous ceremonies. They started off by bantering on what it takes to be a show host, then launched into an "Anything You Can Do I Can Do Better" song-and-dance number. They riffed on everything from pacing to keeping the show on time to improving gift bags.

Harris promised not to do too many "Spider-Man" jokes, but the several he did cut deep.  "I sent Bono" - who composed the show's music with U2 bandmate the Edge - "a congratulatory cable, but it snapped," and "[ousted "Spider-Man" director] Julie Taymor found out it was over when she woke up with the head of 'War Horse' in her bed."