The singer will grant Letterman her first network TV interview on the "Late Show" on March 29, the show announced Thursday.
Starting that week, Jackson is making a round of media appearances to promote her new album, "Damita Jo." She'll appear on ABC's "Good Morning America" and Fox's "On the Air With Ryan Seacrest."
She'll also be on NBC's "Saturday Night Live."
Her appearance on Letterman is a coup for the talk-show host, considering it was also on CBS where Jackson had her controversial Super Bowl halftime show exposure. She later stayed away from the Grammy Awards on CBS, reportedly because the network wanted her to apologize for the Super Bowl performance.
Letterman's show is pre-taped, allowing for editing. WhenWednesday and lifted her shirt to expose her breasts, the shot was edited to obscure the view.
Jackson will be Seacrest's sole guest and will perform for a crowd outside the Hollywood-area complex where the show is taped.
Fox spokesman John Rizzotti said it was uncertain whether she'll perform one or two songs after Seacrest (also host of Fox's "American Idol") interviews her.
A seven-second delay, standard for the show, will be in place for her April 2 appearance, Rizzotti said.
The fallout from Jackson's Super Bowl antics has been extensive, with the public and politicians clamoring for the TV industry to clean up its act.