An accelerated release of Fentanyl from a 25 mcg/hour patch can lead to adverse events for at-risk patients, including excessive sedation, respiratory depression, hypoventilation (slow breathing), and apnea (temporary suspension of breathing). The patches are packaged individually and boxed in quantities of five patches per box.In plain English, fentanyl can stop your breathing completely and permanently. This is not an unusual event with fentanyl. Wilco songwriter Jay Bennett was killed by a fentanyl patch. Fifty-six patients at this Kansas clinic were killed by fentanyl overdoses. Johnson & Johnson (JNJ) lost a series of cases in which patients died taking Duragesic, the original branded version of fentanyl.
The latest recall occurred because the patches released the drug too quickly. But the total number of recalls -- especially if you consider the nine recalls of the Daytrana patch for ADHD, that Shire (SHPGY) literally gave up making that product because it wasn't reliable enough, and that J&J has settled all its suits on another patch product, the Ortho Evra birth control patch, because that product also delivered too much medicine too quickly -- strongly indicates that transdermal patches are an inherently problematic way of delivering drugs. Time for the FDA to act.
- Cephalon's Lollipops of Death: 56 Patients at One Clinic Die of Off-Label Painkiller Use
- J&J Q3: Duragesic Sales Down 20% Following Fentanyl Patch Death Warnings
- Watson's Fentanyl Patch Recall Is 6th So Far; Why Don't Patches Work?
- Wilco's Bennett Killed by Fentanyl; Is It Time to Tighten Rules on Patch Drugs?
- Duragesic Recall Causes More Patch Woes for J&J
- J&J Loses 3rd Duragesic/Fentanyl Patch Death Case; $16.5 Mil. Verdict
- J&J Settles Fatal Patch Cases, So Why Is This Thing Still on the Market?