Oscar-nominee Amy Adams ("The Fighter") will portray the smart, enterprising romantic rival to Clark Kent/Superman, who will be played by British actor Henry Cavill ("The Tudors"), in Zack Snyder's upcoming reboot of the superhero franchise.
So, what do you think of the matchup?
Here's a look at some other stars who have played the pair:
-Kirk Alyn and Noel Neill in the serials "Superman" (1948) and "Atom Man vs. Superman" (1950).
-George Reeves and Phyllis Coates in "Superman and the Mole Men" (1951).
-Christopher Reeve and Margot Kidder in the Superman films of the 1970s and 1980s.
-Dean Cain and Teri Hatcher in TV's "Lois & Clark: The New Adventures of Superman" (1993-1997).
-Tom Welling and Erica Durance in TV's "Smallville" (2001-2011)
-Brandon Routh and Kate Bosworth in 2006's "Superman Returns."
Do you think Adams and Cavill will make a good Lois and Clark? How do they match up to other incarnations of the pair? Vote in our poll and tell us your thoughts in the comments.
Watch the CBSNews.com report here: