The drugs are used to suppress the hormone testosterone, which fuels the growth of prostate cancer tumors. Occasionally the drugs are used by women to treat pain from uterine fibroids.
The FDA says it has not conclusively linked the drugs to health problems, but preliminary data from six studies showed slightly higher rates of diabetes and heart disease in patients taking the drugs.
The agency recommends doctors monitor patients carefully for early signs of diabetes and heart disease.
Drugs under scrutiny include AstraZeneca's Zoladex, Pfizer's Synarel and Abbott Laboratory's Lupron, among others.