The weekly hour-long "Spread Entertainment" will debut May 17 from the Dragonfly nightclub in Hollywood.
"It's like a looser version of 'Donahue' in a nightclub," where the studio audience can get up for a drink or a smoke during the show, Navarro said Tuesday. "I wanted to create a party atmosphere."
Navarro already has an FM radio show plus an Internet radio show broadcast from his home through a Web site with his blog and podcasts.
The 39-year-old former Red Hot Chili Peppers and Jane's Addiction guitarist said he was attracted to doing a show on the Internet, where there's no censorship and more freedom.
"It's time for people to take back what it is they want to see," he said.
"I want to use the Internet to support artists and see things that are out there that other corporate structures aren't allowing us to see. It seems with satellite TV, the Internet, magazines there's almost so many options, and we're only seeing the same five things."
Audience members will be able to ask questions of guests.
"I'm more interested in getting into interesting conversations with interesting people rather than having a band on because they have a CD to promote," Navarro said.