He's a nominee again this year for outstanding supporting actor in a comedy series for his portrayal of Malcolm's dad Hal in Fox's "Malcolm in the Middle."
Cranston was nominated for his work in 2002 and 2003, but he has yet to take home an award.
The son of 1950's television actor Joe Cranston, Bryan grew up in the Los Angeles area. He began his acting career in community theater productions following college, and then joined the original cast of the soap opera "Loving" in 1982.
He appeared on numerous television programs through the 80s and 90s and on the big screen in "That Thing You Do" and "Saving Private Ryan."
Cranston has been a cast member of "Malcolm in the Middle" since its debut in 2000. The series ended its six-year run this year.