Detectives are investigating the suspicious deaths of two people found inside a Pembroke Pines home Wednesday afternoon, authorities said.

Officers and fire rescue crews responded to a 911 call at 4:30 p.m. reporting an unconscious and unresponsive man inside a garage at 1730 NW 109 Avenue, according to Pembroke Pines police.

Authorities said when officers arrived, they found Octavis Anthony Myers, who appeared to have been deceased for some time.

While searching the home to ensure no one else was in need of help, officers discovered a woman dead in a bedroom. Her identity is being withheld until her family is notified, police said.

Investigators said preliminary information indicates the deaths are criminal in nature.

Grandson's whereabouts unknown

Police also noted concern for the wellbeing of 27-year-old Isaiah Collins, the grandson of the homeowner, whose whereabouts remain unknown. Authorities said Collins "frequently lives with his grandmother."

Detectives are asking the public and media for help in locating him.

Anyone with information is urged to call the Pembroke Pines Police Department at 954-431-2200, email tips@ppines.com, or contact Broward Crime Stoppers at 954-493-TIPS.

Neighbors react to scene

CBS News Miami spoke with Kathy Bunbury, a neighbor, who said, "We knew what was happening here was very serious. We know the homeowners. They have been living in that house for 50 years. I saw that their grandson was living with them."

Bunbury said she spoke with police and believed the deaths were criminal in nature. She added, "Police were asking about the cars that were there and if my husband noticed any strange vehicles coming there. We are very, very upset. These are our neighbors and people we know."

Another neighbor, John Jayme, said, "It is messed up. That is really sad. That's crazy. The question would be why—why did this happen?"

Broward County property records show that the home is owned by Samuel and Carrie Collins. It's not clear what connection they have to the victim, Octavis Myers.

Investigation is ongoing

CBS News Miami also spoke with Capt. Adam Feiner of the Pembroke Pines Police Department who said, "The relationship between the property owner and the victim we are not able to discuss because this investigation is ongoing."

While property records show that Samuel and Carrie Collins are the property owners, Feiner said police were told the wife was the current property owner.

He also said, "Isaiah does live there and we have grave concerns for his safety. It is very unusual that he has not been heard from. His family has not heard from him in 2 or 3 days since the investigation began and our detectives have not been able to get a hold of him. So we are very concerned that he, too, could be a victim of a crime."